L-Methionine
- Formula: C5H11NO2S
- Molecular weight: 149.211
- IUPAC Standard InChIKey: FFEARJCKVFRZRR-SCSAIBSYSA-N
- CAS Registry Number: 63-68-3
- Chemical structure:
This structure is also available as a 2d Mol file - Stereoisomers:
- Other names: Methionine; Methionine, L-; γ-Methylthio-α-aminobutyric acid; Butanoic acid, 2-amino-4-(methylthio)-, (S)-; Cymethion; L-(-)-Methionine; Met; S-Methionine; 2-Amino-4-(methylthio)butyric acid; Butyric acid, 2-amino-4-(methylthio)-; L(-)-Amino-γ-methylthiobutyric acid; L-α-Amino-γ-methylmercaptobutyric acid; L-γ-Methylthio-α-aminobutyric acid; 2-Amino-4-methylthiobutanoic acid; Liquimeth; Acimethin; L-2-Amino-4-(methylthio)butyric acid; (S)-2-Amino-4-(methylthio)butanoic acid; h-Met-oh; L-Homocysteine, S-methyl-; NSC 22946; 2-Amino-4-methylthiobutanoic acid (S)-
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Gas phase thermochemistry data
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein
Quantity | Value | Units | Method | Reference | Comment |
---|---|---|---|---|---|
ΔfH°gas | -98.83 ± 0.98 | kcal/mol | Ccr | Sabbah and Minadakis, 1981 |
Condensed phase thermochemistry data
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein
Quantity | Value | Units | Method | Reference | Comment |
---|---|---|---|---|---|
ΔfH°solid | -138.0 ± 0.2 | kcal/mol | Ccr | Sabbah and Minadakis, 1981 | |
Quantity | Value | Units | Method | Reference | Comment |
ΔcH°solid | -851.84 ± 0.15 | kcal/mol | Ccr | Sabbah and Minadakis, 1981 | |
ΔcH°solid | -759.2 ± 0.2 | kcal/mol | Ccb | Tsuzuki, Harper, et al., 1958 |
Phase change data
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled as indicated in comments:
ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein
AC - William E. Acree, Jr., James S. Chickos
Quantity | Value | Units | Method | Reference | Comment |
---|---|---|---|---|---|
ΔsubH° | 39.2 ± 1. | kcal/mol | C | Sabbah and Minadakis, 1981 | ALS |
ΔsubH° | 39.2 ± 1. | kcal/mol | C | Sabbah and Minadakis, 1981 | AC |
Enthalpy of sublimation
ΔsubH (kcal/mol) | Temperature (K) | Method | Reference | Comment |
---|---|---|---|---|
29.9 | 474. | A | Stephenson and Malanowski, 1987 | Based on data from 463. to 485. K.; AC |
29.9 ± 0.2 | 455. | V | Svec and Clyde, 1965 | ALS |
Gas phase ion energetics data
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data evaluated as indicated in comments:
HL - Edward P. Hunter and Sharon G. Lias
Data compiled as indicated in comments:
LBLHLM - Sharon G. Lias, John E. Bartmess, Joel F. Liebman, John L. Holmes, Rhoda D. Levin, and W. Gary Mallard
RDSH - Henry M. Rosenstock, Keith Draxl, Bruce W. Steiner, and John T. Herron
Quantity | Value | Units | Method | Reference | Comment |
---|---|---|---|---|---|
Proton affinity (review) | 223.6 | kcal/mol | N/A | Hunter and Lias, 1998 | HL |
Quantity | Value | Units | Method | Reference | Comment |
Gas basicity | 215.5 | kcal/mol | N/A | Hunter and Lias, 1998 | HL |
Ionization energy determinations
IE (eV) | Method | Reference | Comment |
---|---|---|---|
8.3 | PE | Cannington and Ham, 1983 | LBLHLM |
8.63 ± 0.10 | EI | Svec and Junk, 1967 | RDSH |
~9. | PI | Akopyan and Loginov, 1967 | RDSH |
8.65 | PE | Cannington and Ham, 1983 | Vertical value; LBLHLM |
Appearance energy determinations
Ion | AE (eV) | Other Products | Method | Reference | Comment |
---|---|---|---|---|---|
CH3S+ | 13.0 ± 0.2 | ? | EI | Svec and Junk, 1967 | RDSH |
C2H5S+ | 12.43 ± 0.10 | ? | EI | Svec and Junk, 1967 | RDSH |
C4H10NS+ | 9.68 ± 0.15 | ? | EI | Svec and Junk, 1967 | RDSH |
Mass spectrum (electron ionization)
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
Spectrum
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Additional Data
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Due to licensing restrictions, this spectrum cannot be downloaded.
Owner | NIST Mass Spectrometry Data Center Collection (C) 2014 copyright by the U.S. Secretary of Commerce on behalf of the United States of America. All rights reserved. |
---|---|
Origin | Chemical Concepts |
NIST MS number | 191948 |
UV/Visible spectrum
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Spectrum
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Additional Data
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Source | Johnson, 1971 |
---|---|
Owner | INEP CP RAS, NIST OSRD Collection (C) 2007 copyright by the U.S. Secretary of Commerce on behalf of the United States of America. All rights reserved. |
Origin | INSTITUTE OF ENERGY PROBLEMS OF CHEMICAL PHYSICS, RAS |
Source reference | RAS UV No. 19870 |
Instrument | Unicam SP 500 |
Boiling point | 283 dec. |
References
Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, NIST Free Links, NIST Subscription Links, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Sabbah and Minadakis, 1981
Sabbah, R.; Minadakis, C.,
Thermodynamique de substances soufrees. II. Etude thermochimique de la l-cysteine et de la l-methionine,
Thermochim. Acta, 1981, 43, 269-277. [all data]
Tsuzuki, Harper, et al., 1958
Tsuzuki, T.; Harper, D.O.; Hunt, H.,
Heats of combustion. VII. The heats of combustion of some amino acids,
J. Phys. Chem., 1958, 62, 1594-1595. [all data]
Stephenson and Malanowski, 1987
Stephenson, Richard M.; Malanowski, Stanislaw,
Handbook of the Thermodynamics of Organic Compounds, 1987, https://doi.org/10.1007/978-94-009-3173-2
. [all data]
Svec and Clyde, 1965
Svec, H.J.; Clyde, D.D.,
Vapor pressures of some α-amino acids,
J. Chem. Eng. Data, 1965, 10, 151. [all data]
Hunter and Lias, 1998
Hunter, E.P.; Lias, S.G.,
Evaluated Gas Phase Basicities and Proton Affinities of Molecules: An Update,
J. Phys. Chem. Ref. Data, 1998, 27, 3, 413-656, https://doi.org/10.1063/1.556018
. [all data]
Cannington and Ham, 1983
Cannington, P.H.; Ham, N.S.,
He(I) and He(II) photoelectron spectra of glycine and related molecules,
J. Electron Spectrosc. Relat. Phenom., 1983, 32, 139. [all data]
Svec and Junk, 1967
Svec, H.J.; Junk, G.A.,
Electron-impact studies of substituted alkanes,
J. Am. Chem. Soc., 1967, 89, 790. [all data]
Akopyan and Loginov, 1967
Akopyan, M.E.; Loginov, Yy.V.,
Mass-spectrometric study of the phoionization of free α-aminoacids,
High Energy Chem., 1967, 1, 83, In original 97. [all data]
Johnson, 1971
Johnson, E.A.,
UV atlas of organic compounds, 1971, 5, J2/4. [all data]
Notes
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- Symbols used in this document:
AE Appearance energy ΔcH°solid Enthalpy of combustion of solid at standard conditions ΔfH°gas Enthalpy of formation of gas at standard conditions ΔfH°solid Enthalpy of formation of solid at standard conditions ΔsubH Enthalpy of sublimation ΔsubH° Enthalpy of sublimation at standard conditions - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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