Pyrazine

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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
BS - Robert L. Brown and Stephen E. Stein
TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director
AC - William E. Acree, Jr., James S. Chickos
ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein
DRB - Donald R. Burgess, Jr.
DH - Eugene S. Domalski and Elizabeth D. Hearing

Quantity Value Units Method Reference Comment
Tboil388.7KN/AAldrich Chemical Company Inc., 1990BS
Tboil388.65KN/AAnderson and Shimanskaya, 1969Uncertainty assigned by TRC = 1. K; TRC
Tboil390.35KN/ALecat, 1947Uncertainty assigned by TRC = 0.5 K; TRC
Quantity Value Units Method Reference Comment
Tfus324.KN/ABougeard, LeCalve, et al., 1978Crystal phase 1 phase; Uncertainty assigned by TRC = 0.1 K; TRC
Tfus320.15KN/ABruhl, 1897Uncertainty assigned by TRC = 1. K; TRC
Tfus334.05KN/ABruhl, 1897Uncertainty assigned by TRC = 6. K; TRC
Quantity Value Units Method Reference Comment
Δvap40.5 ± 1.7kJ/molCGCLipkind and Chickos, 2009Based on data from 342. to 373. K. See also Lipkind and Chickos, 2009, 2.; AC
Δvap56.27 ± 0.46kJ/molCTjebbes, 1962ALS
Δvap56.3kJ/molN/ATjebbes, 1962DRB

Reduced pressure boiling point

Tboil (K) Pressure (bar) Reference Comment
388.71.02Weast and Grasselli, 1989BS

Enthalpy of vaporization

ΔvapH (kJ/mol) Temperature (K) Method Reference Comment
38.8 ± 0.1340.EBSteele, Chirico, et al., 2002Based on data from 354. to 426. K.; AC
36.5 ± 0.2380.EBSteele, Chirico, et al., 2002Based on data from 354. to 426. K.; AC
34.1 ± 0.4420.EBSteele, Chirico, et al., 2002Based on data from 354. to 426. K.; AC
37.9352.N/ASakoguchi, Ueoka, et al., 1995Based on data from 332. to 373. K.; AC

Enthalpy of sublimation

ΔsubH (kJ/mol) Temperature (K) Reference Comment
56.2303.Sakoguchi, Ueoka, et al., 1995Based on data from 288. to 317. K.; AC

Enthalpy of fusion

ΔfusH (kJ/mol) Temperature (K) Method Reference Comment
14.78325.4ACChirico, Knipmeyer, et al., 2003Based on data from 5. to 380. K.; AC
12.95328.2N/ABougeard, Calve, et al., 1978AC

Enthalpy of phase transition

ΔHtrs (kJ/mol) Temperature (K) Initial Phase Final Phase Reference Comment
0.969300.6crystaline, IIIcrystaline, IIBoyd, Comper, et al., 1979DH
0.060310.crystaline, IIcrystaline, IBoyd, Comper, et al., 1979DH

Entropy of phase transition

ΔStrs (J/mol*K) Temperature (K) Initial Phase Final Phase Reference Comment
3.22300.6crystaline, IIIcrystaline, IIBoyd, Comper, et al., 1979DH
0.2310.crystaline, IIcrystaline, IBoyd, Comper, et al., 1979DH

In addition to the Thermodynamics Research Center (TRC) data available from this site, much more physical and chemical property data is available from the following TRC products:


Gas phase ion energetics data

Go To: Top, Phase change data, References, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data evaluated as indicated in comments:
HL - Edward P. Hunter and Sharon G. Lias

Data compiled as indicated in comments:
B - John E. Bartmess
LBLHLM - Sharon G. Lias, John E. Bartmess, Joel F. Liebman, John L. Holmes, Rhoda D. Levin, and W. Gary Mallard
LLK - Sharon G. Lias, Rhoda D. Levin, and Sherif A. Kafafi
RDSH - Henry M. Rosenstock, Keith Draxl, Bruce W. Steiner, and John T. Herron

View reactions leading to C4H4N2+ (ion structure unspecified)

Quantity Value Units Method Reference Comment
Proton affinity (review)877.1kJ/molN/AHunter and Lias, 1998HL
Quantity Value Units Method Reference Comment
Gas basicity847.0kJ/molN/AHunter and Lias, 1998HL

Electron affinity determinations

EA (eV) Method Reference Comment
>-0.065004ETSNenner and Schultz, 1975Pyrazine. EA estimated as 0.124 eV based on soln phase electrochemical correlations. G3MP2B3 calculations put EA ca. 0 eV; B

Ionization energy determinations

IE (eV) Method Reference Comment
9.0PEPiancastelli, Keller, et al., 1983LBLHLM
9.28 ± 0.01SScheps, Florida, et al., 1972LLK
9.29PEGleiter, Heilbronner, et al., 1972LLK
9.216PEAsbrink, Lindholm, et al., 1970RDSH
9.28 ± 0.05PEEland, 1969RDSH
9.36PEDewar and Worley, 1969RDSH
9.29 ± 0.01PIYencha and El-Sayed, 1968RDSH
9.29 ± 0.03SParkin and Innes, 1965RDSH
9.63PESuffolk, 1974Vertical value; LLK
9.63PEGleiter, Heilbronner, et al., 1970Vertical value; RDSH

Appearance energy determinations

Ion AE (eV) Other Products MethodReferenceComment
C3H2N+15.25 ± 0.10?EIMomigny, Urbain, et al., 1965RDSH
C3H3N+12.81 ± 0.10HCNEIMomigny, Urbain, et al., 1965RDSH
C4H3N2+13.68 ± 0.10HEIMomigny, Urbain, et al., 1965RDSH

De-protonation reactions

C4H3N2- + Hydrogen cation = Pyrazine

By formula: C4H3N2- + H+ = C4H4N2

Quantity Value Units Method Reference Comment
Δr1643. ± 10.kJ/molTDEqMeot-ner and Kafafi, 1988gas phase; anchored to 88MEO scale, not the "87 acidity scale". The Kiefer, Zhang, et al., 1997 BDE is for ortho.; B
Quantity Value Units Method Reference Comment
Δr1604.6 ± 1.7kJ/molN/AWren, Vogelhuber, et al., 2012gas phase; B
Δr1603. ± 8.4kJ/molTDEqMeot-ner and Kafafi, 1988gas phase; anchored to 88MEO scale, not the "87 acidity scale". The Kiefer, Zhang, et al., 1997 BDE is for ortho.; B

References

Go To: Top, Phase change data, Gas phase ion energetics data, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Aldrich Chemical Company Inc., 1990
Aldrich Chemical Company Inc., Catalog Handbook of Fine Chemicals, Aldrich Chemical Company, Inc., Milwaukee WI, 1990, 1. [all data]

Anderson and Shimanskaya, 1969
Anderson, A.A.; Shimanskaya, M.V., Gas-Liquid Chromatography of some Aliphatic and Heterocyclic Polyfunctional Amines: II. Solution Thermodyn. of Amines in Fix. Phas., Latv. PSR Zinat. Akad. Vestis, Kim. Ser., 1969, No. 5, 527. [all data]

Lecat, 1947
Lecat, M., Some azeotropes of which one constituant is heterocyclic nitrogen, Ann. Soc. Sci. Bruxelles, Ser. 1, 1947, 61, 73. [all data]

Bougeard, LeCalve, et al., 1978
Bougeard, D.; LeCalve, N.; Novak, A.; Bachanh, N., Phase transitions of pyrazine., Mol. Cryst. Liq. Cryst., 1978, 44, 113. [all data]

Bruhl, 1897
Bruhl, J.W., Spectrochemistry of nitrogen containing compounds V, Z. Phys. Chem., Stoechiom. Verwandtschaftsl., 1897, 22, 373. [all data]

Lipkind and Chickos, 2009
Lipkind, Dmitri; Chickos, James S., An examination of the vaporization enthalpies and vapor pressures of pyrazine, pyrimidine, pyridazine, and 1,3,5-triazine, Struct Chem, 2009, 20, 1, 49-58, https://doi.org/10.1007/s11224-008-9389-5 . [all data]

Lipkind and Chickos, 2009, 2
Lipkind, D.; Chickos, J.S., , Abstract from 38th Great Lakes Regional Meeting of the American Chemical Society, May 13-16, Chicago, IL, 2009, GLRM-275. [all data]

Tjebbes, 1962
Tjebbes, J., The heats of combustion and formation of the three diazines and their resonance energies, Acta Chem. Scand., 1962, 16, 916-921. [all data]

Weast and Grasselli, 1989
CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. [all data]

Steele, Chirico, et al., 2002
Steele, W.V.; Chirico, R.D.; Knipmeyer, S.E.; Nguyen, A., Measurements of Vapor Pressure, Heat Capacity, and Density along the Saturation Line for γ-Caprolactam, Pyrazine, 1,2-Propanediol, Triethylene Glycol, Phenyl Acetylene, and Diphenyl Acetylene, J. Chem. Eng. Data, 2002, 47, 4, 689-699, https://doi.org/10.1021/je010085z . [all data]

Sakoguchi, Ueoka, et al., 1995
Sakoguchi, Akihiro; Ueoka, Ryuichi; Kato, Yasuo; Arai, Yasuhiko, Vapor Pressures of Alkylpyridines and Alkylpyrazines., KAGAKU KOGAKU RONBUNSHU, 1995, 21, 1, 219-223, https://doi.org/10.1252/kakoronbunshu.21.219 . [all data]

Chirico, Knipmeyer, et al., 2003
Chirico, R.D.; Knipmeyer, S.E.; Steele, W.V., Heat capacities, enthalpy increments, and derived thermodynamic functions for pyrazine between the temperatures 5K and 380K, The Journal of Chemical Thermodynamics, 2003, 35, 7, 1059-1072, https://doi.org/10.1016/S0021-9614(03)00041-7 . [all data]

Bougeard, Calve, et al., 1978
Bougeard, D.; Calve, N. Le; Novak, A.; Nguyen-ba-chanh, A., Phase Transitions of Pyrazine, GMCL, 1978, 44, 1, 113-123, https://doi.org/10.1080/15421407808083935 . [all data]

Boyd, Comper, et al., 1979
Boyd, R.K.; Comper, J.; Ferguson, G., Entropy changes and structural implications for crystalline phases of pyrazine, Can. J. Chem., 1979, 57, 3056-3060. [all data]

Hunter and Lias, 1998
Hunter, E.P.; Lias, S.G., Evaluated Gas Phase Basicities and Proton Affinities of Molecules: An Update, J. Phys. Chem. Ref. Data, 1998, 27, 3, 413-656, https://doi.org/10.1063/1.556018 . [all data]

Nenner and Schultz, 1975
Nenner, I.; Schultz, G.J., Temporary negative ions and electron affinities of benzene and N-heterocyclic molecules: Pyridine, pyridazine, pyrimidine, pyrazine, and s-triazine, J. Chem. Phys., 1975, 62, 1747. [all data]

Piancastelli, Keller, et al., 1983
Piancastelli, M.N.; Keller, P.R.; Taylor, J.W.; Grimm, F.A.; Carlson, T.A., Angular distribution parameter as a function of photon energy for some mono- and diazabenzenes and its use for orbital assignment, J. Am. Chem. Soc., 1983, 105, 4235. [all data]

Scheps, Florida, et al., 1972
Scheps, R.; Florida, D.; Rice, S.A., Comments on the Rydberg spectrum of pyrazine, J. Mol. Spectrosc., 1972, 44, 1. [all data]

Gleiter, Heilbronner, et al., 1972
Gleiter, R.; Heilbronner, E.; Hornung, V., Photoelectron spectra of azabenzenes azanaphthalenes: I. Pyridine, diazines s-triazine and s-tetrazine, Helv. Chim. Acta, 1972, 55, 255. [all data]

Asbrink, Lindholm, et al., 1970
Asbrink, L.; Lindholm, E.; Edqvist, O., Jahn-Teller effect in the vibrational structure of the photoelectron spectrum of benzene, Chem. Phys. Lett., 1970, 5, 609. [all data]

Eland, 1969
Eland, J.H.D., Photoelectron spectra of conjugated hydrocarbons and heteromolecules, Intern. J. Mass Spectrom. Ion Phys., 1969, 2, 471. [all data]

Dewar and Worley, 1969
Dewar, M.J.S.; Worley, S.D., Photoelectron spectra of molecules. II.The ionization potentials of azabenzenes and azanaphthalenes, J. Chem. Phys., 1969, 51, 263. [all data]

Yencha and El-Sayed, 1968
Yencha, A.J.; El-Sayed, M.A., Lowest ionization potentials of some nitrogen heterocyclics, J. Chem. Phys., 1968, 48, 3469. [all data]

Parkin and Innes, 1965
Parkin, J.E.; Innes, K.K., The vacuum ultraviolet spectra of pyrazine, pyrimidine, and pyridazine vapors. Part I. Spectra between 1550 A and 2000 A, J. Mol. Spectry., 1965, 15, 407. [all data]

Suffolk, 1974
Suffolk, R.J., The photoelectron spectra of the perfluorodiazines, J. Electron Spectrosc. Relat. Phenom., 1974, 3, 53. [all data]

Gleiter, Heilbronner, et al., 1970
Gleiter, R.; Heilbronner, E.; Hornung, V., Lone pair interaction in pyridazine, pyrimidine, and pyrazine, Angew. Chem. Int. Ed. Engl., 1970, 9, 901. [all data]

Momigny, Urbain, et al., 1965
Momigny, J.; Urbain, J.; Wankenne, H., Les effets de l'impact electronique sur la pyridine et les diazines isomeres, Bull. Soc. Roy. Sci. Liege, 1965, 34, 337. [all data]

Meot-ner and Kafafi, 1988
Meot-ner, M.; Kafafi, S.A., Carbon Acidities of Aromatic Compounds, J. Am. Chem. Soc., 1988, 110, 19, 6297, https://doi.org/10.1021/ja00227a003 . [all data]

Kiefer, Zhang, et al., 1997
Kiefer, J.H.; Zhang, Q.; Kern, R.D.; Yao, J.; Jursic, B., Pyrolysis of Aromatic Azines: Pyrazine, Pyrimidine, and Pyridine, J. Phys. Chem. A, 1997, 101, 38, 7061, https://doi.org/10.1021/jp970211z . [all data]

Wren, Vogelhuber, et al., 2012
Wren, S.W.; Vogelhuber, K.M.; Garver, J.M.; Kato, S.; Sheps, L.; Bierbaum, V.M.; Lineberger, W.C., C-H Bond Strengths and Acidities in Aromatic Systems: Effects of Nitrogen Incorporation in Mono-, Di-, and Triazines, J. Am. Chem. Soc., 2012, 134, 15, 6584-6595, https://doi.org/10.1021/ja209566q . [all data]


Notes

Go To: Top, Phase change data, Gas phase ion energetics data, References