5-Fluorouracil
- Formula: C4H3FN2O2
- Molecular weight: 130.0772
- IUPAC Standard InChIKey: GHASVSINZRGABV-UHFFFAOYSA-N
- CAS Registry Number: 51-21-8
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Other names: 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-; Fluorouracil; Uracil, 5-fluoro-; Efudex; Fluoroplex; Fluracil; Fluril; NSC 19893; Ro 2-9757; 5-Fluoro-2,4(1H,3H)-Pyrimidinedione; 5-FU; Arumel; Carzonal; Effluderm (free base); Efudix; Fluoroblastin; Fluri; FU; Kecimeton; Timazin; U-8953; Ulup; 5-Fluoro-2,4-pyrimidinedione; 5-Fluoropyrimidine-2,4-dione; 5-Ftouracyl; Adrucil; Effluderm; Efurix; 5-Fluoracil; 5-Fluor-2,4-dihydroxypyrimidin; 5-Fluor-2,4-pyrimidindiol; 5-Fluoruracil; Fluracilum; Ftoruracil; Queroplex; 2,4-Pyrimidinedione, 5-fluoro-; 5-Fluoropyrimidine-2,4-diol; Carac
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Phase change data
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: William E. Acree, Jr., James S. Chickos
Quantity | Value | Units | Method | Reference | Comment |
---|---|---|---|---|---|
ΔsubH° | 133.2 ± 2.1 | kJ/mol | ME | Szterner, Kaminski, et al., 2002 | See also Zielenkiewicz and Szterner, 2005. |
Enthalpy of sublimation
ΔsubH (kJ/mol) | Temperature (K) | Method | Reference |
---|---|---|---|
150. ± 2. | 421. to 483. | TE | Brunetti, Portalone, et al., 2002 |
129.9 | 394. to 401. | ME | Szterner, Kaminski, et al., 2002 |
References
Go To: Top, Phase change data, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Szterner, Kaminski, et al., 2002
Szterner, Piotr; Kaminski, Miron; Zielenkiewicz, Anna,
Vapour pressures, molar enthalpies of sublimation and molar enthalpies of solution in water of five halogenated derivatives of uracil,
The Journal of Chemical Thermodynamics, 2002, 34, 7, 1005-1012, https://doi.org/10.1006/jcht.2000.0987
. [all data]
Zielenkiewicz and Szterner, 2005
Zielenkiewicz, Wojciech; Szterner, Piotr,
Thermodynamic Investigation of Uracil and Its Halo Derivatives. Enthalpies of Solution and Solvation in Methanol,
J. Chem. Eng. Data, 2005, 50, 4, 1139-1143, https://doi.org/10.1021/je049656o
. [all data]
Brunetti, Portalone, et al., 2002
Brunetti, B.; Portalone, G.; Piacente, V.,
Sublimation Thermodynamic Parameters for 5-Fluorouracil and Its 1-Methyl and 1,3-Dimethyl Derivatives from Vapor Pressure Measurements,
J. Chem. Eng. Data, 2002, 47, 1, 17-19, https://doi.org/10.1021/je010037e
. [all data]
Notes
Go To: Top, Phase change data, References
- Symbols used in this document:
ΔsubH Enthalpy of sublimation ΔsubH° Enthalpy of sublimation at standard conditions - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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