Tromethamine
- Formula: C4H11NO3
- Molecular weight: 121.1350
- IUPAC Standard InChIKey: LENZDBCJOHFCAS-UHFFFAOYSA-N
- CAS Registry Number: 77-86-1
- Chemical structure:
This structure is also available as a 2d Mol file - Other names: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-; Addex-Tham; Aminotrimethylolmethane; Aminotris(hydroxymethyl)methane; Methanamine, 1,1,1-tris(hydroxymethyl)-; Pehanorm; Talatrol; Tham-E; Trimethylolaminomethane; Tris; Tris amino; Tris buffer; Tris(hydroxymethyl)aminomethane; Tris(hydroxymethyl)methanamine; Tris(hydroxymethyl)methylamine; Tris-steril; Trisamin; Trisamine; Trisaminol; Trispuffer; Trizma; Trometamol; Trometamole; Tromethane; Tromethanmin; Tutofusin tris; THAM; Apiroserum Tham; Methylamine, 1,1,1-tris(hydroxymethyl)-; 2-(Hydroxymethyl)-2-amino-1,3-propanediol; 2-Amino-2-(hydroxymethyl)propane-1,3-diol; 2-Amino-2-methylol-1,3-propanediol; Tromethamin; Aminotri(hydroxymethyl)methane; TAM; Trigmo base; Triladyl; 2-Amino-2-hydroxymethylpropanediol; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Tris (hydroxymethyl)aminoethane; Tris base; Tris, free base; Trizma base; NSC 6365; Tris (buffering agent)
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Phase change data
Go To: Top, IR Spectrum, Mass spectrum (electron ionization), References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled as indicated in comments:
BS - Robert L. Brown and Stephen E. Stein
TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director
AC - William E. Acree, Jr., James S. Chickos
DH - Eugene S. Domalski and Elizabeth D. Hearing
Quantity | Value | Units | Method | Reference | Comment |
---|---|---|---|---|---|
Tfus | 440.7 | K | N/A | Murrill and Breed, 1970 | Crystal phase 1 phase; Uncertainty assigned by TRC = 3. K; TRC |
Quantity | Value | Units | Method | Reference | Comment |
Ttriple | 443.6 | K | N/A | Zhang and Yang, 1990 | Crystal phase 1 phase; Uncertainty assigned by TRC = 0.1 K; TRC |
Reduced pressure boiling point
Tboil (K) | Pressure (atm) | Reference | Comment |
---|---|---|---|
492.7 | 0.013 | Weast and Grasselli, 1989 | BS |
Enthalpy of fusion
ΔfusH (kcal/mol) | Temperature (K) | Method | Reference | Comment |
---|---|---|---|---|
0.74 | 444.6 | DSC | Divi, Chellappa, et al., 2006 | AC |
0.576 | 443.6 | N/A | Zhang Zhi Ying and Yang Meng Lin, 1990 | See also López, Van Braak, et al., 1994.; AC |
Temperature of phase transition
Ttrs (K) | Initial Phase | Final Phase | Reference | Comment |
---|---|---|---|---|
407.56 | crystaline, II | crystaline, I | Ying and Lin, 1990 | DH |
Enthalpy of phase transition
ΔHtrs (kcal/mol) | Temperature (K) | Initial Phase | Final Phase | Reference | Comment |
---|---|---|---|---|---|
7.9866 | 407.44 | crystaline, II | crystaline, I | Ying and Lin, 1990 | Bifurcated transition.; DH |
0.5753 | 443.4 | crystaline, I | liquid | Ying and Lin, 1990 | DH |
8.1888 | 405. | crystaline, II | crystaline, I | Murrill and Breed, 1970, 2 | DH |
0.7268 | 439. | crystaline, I | liquid | Murrill and Breed, 1970, 2 | DH |
Entropy of phase transition
ΔStrs (cal/mol*K) | Temperature (K) | Initial Phase | Final Phase | Reference | Comment |
---|---|---|---|---|---|
20.3 | 405. | crystaline, II | crystaline, I | Murrill and Breed, 1970, 2 | DH |
1.7 | 439. | crystaline, I | liquid | Murrill and Breed, 1970, 2 | DH |
IR Spectrum
Go To: Top, Phase change data, Mass spectrum (electron ionization), References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: Coblentz Society, Inc.
Condensed Phase Spectrum
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Notice: Except where noted, spectra from this collection were measured on dispersive instruments, often in carefully selected solvents, and hence may differ in detail from measurements on FTIR instruments or in other chemical environments. More information on the manner in which spectra in this collection were collected can be found here.
Notice: Concentration information is not available for this spectrum and, therefore, molar absorptivity values cannot be derived.
Additional Data
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Owner | Copyright (C) 1987 by the Coblentz Society Collection (C) 2018 copyright by the U.S. Secretary of Commerce on behalf of the United States of America. All rights reserved. |
---|---|
Origin | WYANDOTTE CHEMICALS CORP. |
Source reference | COBLENTZ NO. 5998 |
Date | Not specified, most likely prior to 1970 |
Name(s) | 2-amino-2-(hydroxymethyl)-1,3-propanediol |
State | SOLID (OIL MULL) |
Instrument | BAIRD (GRATING) |
Instrument parameters | NaCl PRISM |
Path length | CAPILLARY SPECTRAL CONTAMINATION DUE TO OIL AROUND 2900 CM-1 |
Resolution | 2 |
Melting point | 171 C |
Mass spectrum (electron ionization)
Go To: Top, Phase change data, IR Spectrum, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
Spectrum
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Additional Data
View image of digitized spectrum (can be printed in landscape orientation).
Due to licensing restrictions, this spectrum cannot be downloaded.
Owner | NIST Mass Spectrometry Data Center Collection (C) 2014 copyright by the U.S. Secretary of Commerce on behalf of the United States of America. All rights reserved. |
---|---|
Origin | Japan AIST/NIMC Database- Spectrum MS-NW-1766 |
NIST MS number | 229605 |
References
Go To: Top, Phase change data, IR Spectrum, Mass spectrum (electron ionization), Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Murrill and Breed, 1970
Murrill, E.; Breed, L.W.,
Solid-solid phase transitions determined by differential scanning calorime- try. Part I. Tetrahedral Substances.,
Thermochim. Acta, 1970, 1, 239. [all data]
Zhang and Yang, 1990
Zhang, Z.-Y.; Yang, M.-L.,
Heat Capacity and Phase Transitions of 2-Amino-2-hydroxymethyl-propane-1,3- diol from 290 K to 455 K,
J. Chem. Thermodyn., 1990, 22, 617. [all data]
Weast and Grasselli, 1989
CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. [all data]
Divi, Chellappa, et al., 2006
Divi, Suresh; Chellappa, Raja; Chandra, Dhanesh,
Heat capacity measurement of organic thermal energy storage materials,
The Journal of Chemical Thermodynamics, 2006, 38, 11, 1312-1326, https://doi.org/10.1016/j.jct.2006.02.005
. [all data]
Zhang Zhi Ying and Yang Meng Lin, 1990
Zhang Zhi Ying, Manuel João S.; Yang Meng Lin, Manuel João S.,
Heat capacity and phase transitions of 2-amino-2-hydroxymethylpropan-1,3-diol from 290 K to 455 K,
The Journal of Chemical Thermodynamics, 1990, 22, 7, 617-622, https://doi.org/10.1016/0021-9614(90)90014-H
. [all data]
López, Van Braak, et al., 1994
López, D.O.; Van Braak, J.; Tamarit, J.L.L.; Oonk, H.A.J.,
Thermodynamic phase diagram analysis of three binary systems shared by five neopentane derivatives,
Calphad, 1994, 18, 4, 387-396, https://doi.org/10.1016/0364-5916(94)90016-7
. [all data]
Ying and Lin, 1990
Ying, Z.Z.; Lin, Y.M.,
Heat capacity and phase transitions of 2-amino-2-hydroxymethylpropan-1,3-diol from 290 to 455 K,
J. Chem. Thermodynam., 1990, 22, 617-622. [all data]
Murrill and Breed, 1970, 2
Murrill, E.; Breed, L.,
Solid-solid phase transitions determined by differential scanning calorimetry,
Thermochim. Acta, 1970, 1, 239-246. [all data]
Notes
Go To: Top, Phase change data, IR Spectrum, Mass spectrum (electron ionization), References
- Symbols used in this document:
Tboil Boiling point Tfus Fusion (melting) point Ttriple Triple point temperature Ttrs Temperature of phase transition ΔHtrs Enthalpy of phase transition ΔStrs Entropy of phase transition ΔfusH Enthalpy of fusion - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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