Tromethamine

• Formula: C₄H₁₁NO₃
• Molecular weight: 121.1350
• IUPAC Standard InChI: InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2 Copy

  
• IUPAC Standard InChIKey: LENZDBCJOHFCAS-UHFFFAOYSA-N Copy
• CAS Registry Number: 77-86-1
• Chemical structure:
  This structure is also available as a 2d Mol file
• Other names: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-; Addex-Tham; Aminotrimethylolmethane; Aminotris(hydroxymethyl)methane; Methanamine, 1,1,1-tris(hydroxymethyl)-; Pehanorm; Talatrol; Tham-E; Trimethylolaminomethane; Tris; Tris amino; Tris buffer; Tris(hydroxymethyl)aminomethane; Tris(hydroxymethyl)methanamine; Tris(hydroxymethyl)methylamine; Tris-steril; Trisamin; Trisamine; Trisaminol; Trispuffer; Trizma; Trometamol; Trometamole; Tromethane; Tromethanmin; Tutofusin tris; THAM; Apiroserum Tham; Methylamine, 1,1,1-tris(hydroxymethyl)-; 2-(Hydroxymethyl)-2-amino-1,3-propanediol; 2-Amino-2-(hydroxymethyl)propane-1,3-diol; 2-Amino-2-methylol-1,3-propanediol; Tromethamin; Aminotri(hydroxymethyl)methane; TAM; Trigmo base; Triladyl; 2-Amino-2-hydroxymethylpropanediol; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Tris (hydroxymethyl)aminoethane; Tris base; Tris, free base; Trizma base; NSC 6365; Tris (buffering agent)
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• Information on this page:
  • Phase change data
  • Gas Chromatography
  • References
  • Notes
• Other data available:
  • Condensed phase thermochemistry data
  • IR Spectrum
  • Mass spectrum (electron ionization)
  • UV/Visible spectrum
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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
BS - Robert L. Brown and Stephen E. Stein
TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director
AC - William E. Acree, Jr., James S. Chickos
DH - Eugene S. Domalski and Elizabeth D. Hearing

Reduced pressure boiling point

Enthalpy of fusion

Temperature of phase transition

Enthalpy of phase transition

Entropy of phase transition

Gas Chromatography

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Normal alkane RI, non-polar column, custom temperature program

View large format table.

References

Go To: Top, Phase change data, Gas Chromatography, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Murrill and Breed, 1970
Murrill, E.; Breed, L.W., Solid-solid phase transitions determined by differential scanning calorime- try. Part I. Tetrahedral Substances., Thermochim. Acta, 1970, 1, 239. [all data]

Zhang and Yang, 1990
Zhang, Z.-Y.; Yang, M.-L., Heat Capacity and Phase Transitions of 2-Amino-2-hydroxymethyl-propane-1,3- diol from 290 K to 455 K, J. Chem. Thermodyn., 1990, 22, 617. [all data]

Weast and Grasselli, 1989
CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. [all data]

Divi, Chellappa, et al., 2006
Divi, Suresh; Chellappa, Raja; Chandra, Dhanesh, Heat capacity measurement of organic thermal energy storage materials, The Journal of Chemical Thermodynamics, 2006, 38, 11, 1312-1326, https://doi.org/10.1016/j.jct.2006.02.005 . [all data]

Zhang Zhi Ying and Yang Meng Lin, 1990
Zhang Zhi Ying, Manuel João S.; Yang Meng Lin, Manuel João S., Heat capacity and phase transitions of 2-amino-2-hydroxymethylpropan-1,3-diol from 290 K to 455 K, The Journal of Chemical Thermodynamics, 1990, 22, 7, 617-622, https://doi.org/10.1016/0021-9614(90)90014-H . [all data]

López, Van Braak, et al., 1994
López, D.O.; Van Braak, J.; Tamarit, J.L.L.; Oonk, H.A.J., Thermodynamic phase diagram analysis of three binary systems shared by five neopentane derivatives, Calphad, 1994, 18, 4, 387-396, https://doi.org/10.1016/0364-5916(94)90016-7 . [all data]

Ying and Lin, 1990
Ying, Z.Z.; Lin, Y.M., Heat capacity and phase transitions of 2-amino-2-hydroxymethylpropan-1,3-diol from 290 to 455 K, J. Chem. Thermodynam., 1990, 22, 617-622. [all data]

Murrill and Breed, 1970, 2
Murrill, E.; Breed, L., Solid-solid phase transitions determined by differential scanning calorimetry, Thermochim. Acta, 1970, 1, 239-246. [all data]

Ardrey and Moffat, 1981
Ardrey, R.E.; Moffat, A.C., Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase, J. Chromatogr., 1981, 220, 3, 195-252, https://doi.org/10.1016/S0021-9673(00)81925-1 . [all data]

Notes

Go To: Top, Phase change data, Gas Chromatography, References

• Symbols used in this document:
  

  Tboil	Boiling point
  Tfus	Fusion (melting) point
  Ttriple	Triple point temperature
  Ttrs	Temperature of phase transition
  ΔHtrs	Enthalpy of phase transition
  ΔStrs	Entropy of phase transition
  ΔfusH	Enthalpy of fusion

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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