Tromethamine

• Formula: C₄H₁₁NO₃
• Molecular weight: 121.1350
• IUPAC Standard InChI: InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2 Copy

  
• IUPAC Standard InChIKey: LENZDBCJOHFCAS-UHFFFAOYSA-N Copy
• CAS Registry Number: 77-86-1
• Chemical structure:
  This structure is also available as a 2d Mol file
• Other names: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-; Addex-Tham; Aminotrimethylolmethane; Aminotris(hydroxymethyl)methane; Methanamine, 1,1,1-tris(hydroxymethyl)-; Pehanorm; Talatrol; Tham-E; Trimethylolaminomethane; Tris; Tris amino; Tris buffer; Tris(hydroxymethyl)aminomethane; Tris(hydroxymethyl)methanamine; Tris(hydroxymethyl)methylamine; Tris-steril; Trisamin; Trisamine; Trisaminol; Trispuffer; Trizma; Trometamol; Trometamole; Tromethane; Tromethanmin; Tutofusin tris; THAM; Apiroserum Tham; Methylamine, 1,1,1-tris(hydroxymethyl)-; 2-(Hydroxymethyl)-2-amino-1,3-propanediol; 2-Amino-2-(hydroxymethyl)propane-1,3-diol; 2-Amino-2-methylol-1,3-propanediol; Tromethamin; Aminotri(hydroxymethyl)methane; TAM; Trigmo base; Triladyl; 2-Amino-2-hydroxymethylpropanediol; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Tris (hydroxymethyl)aminoethane; Tris base; Tris, free base; Trizma base; NSC 6365; Tris (buffering agent)
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• Information on this page:
  • Condensed phase thermochemistry data
  • Phase change data
  • Gas Chromatography
  • References
  • Notes
• Other data available:
  • IR Spectrum
  • Mass spectrum (electron ionization)
  • UV/Visible spectrum
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Condensed phase thermochemistry data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein
DH - Eugene S. Domalski and Elizabeth D. Hearing

Constant pressure heat capacity of solid

Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
BS - Robert L. Brown and Stephen E. Stein
TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director
AC - William E. Acree, Jr., James S. Chickos
DH - Eugene S. Domalski and Elizabeth D. Hearing

Reduced pressure boiling point

Enthalpy of fusion

Temperature of phase transition

Enthalpy of phase transition

Entropy of phase transition

Gas Chromatography

Go To: Top, Condensed phase thermochemistry data, Phase change data, References, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Normal alkane RI, non-polar column, custom temperature program

View large format table.

References

Go To: Top, Condensed phase thermochemistry data, Phase change data, Gas Chromatography, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Laynez, Ringer, et al., 1970
Laynez, J.; Ringer, B.; Sunner, S., On the accuracy of rotating-bomb combustion calorimetry for organic chlorine and bromine compounds, J. Chem. Thermodyn., 1970, 2, 603-610. [all data]

Xue, Wu, et al., 1985
Xue, R.; Wu, D.; Qu, S., Studies on thermochemistry of porphyrins. I. A precision combustion calorimetric apparatus and calibration, Wuli Huaxue Xuebao, 1985, 1, 76-81. [all data]

Arvidsson and Westrum, 1972
Arvidsson, K.; Westrum, E.F., Jr., Tris(hydroxymethane.yl)aminomethane. Heat capacities and thermodynamic properties from 5 to 350K, J. Chem. Thermodynam., 1972, 4, 449-453. [all data]

Ying and Lin, 1990
Ying, Z.Z.; Lin, Y.M., Heat capacity and phase transitions of 2-amino-2-hydroxymethylpropan-1,3-diol from 290 to 455 K, J. Chem. Thermodynam., 1990, 22, 617-622. [all data]

Murrill and Breed, 1970
Murrill, E.; Breed, L.W., Solid-solid phase transitions determined by differential scanning calorime- try. Part I. Tetrahedral Substances., Thermochim. Acta, 1970, 1, 239. [all data]

Zhang and Yang, 1990
Zhang, Z.-Y.; Yang, M.-L., Heat Capacity and Phase Transitions of 2-Amino-2-hydroxymethyl-propane-1,3- diol from 290 K to 455 K, J. Chem. Thermodyn., 1990, 22, 617. [all data]

Weast and Grasselli, 1989
CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. [all data]

Divi, Chellappa, et al., 2006
Divi, Suresh; Chellappa, Raja; Chandra, Dhanesh, Heat capacity measurement of organic thermal energy storage materials, The Journal of Chemical Thermodynamics, 2006, 38, 11, 1312-1326, https://doi.org/10.1016/j.jct.2006.02.005 . [all data]

Zhang Zhi Ying and Yang Meng Lin, 1990
Zhang Zhi Ying, Manuel João S.; Yang Meng Lin, Manuel João S., Heat capacity and phase transitions of 2-amino-2-hydroxymethylpropan-1,3-diol from 290 K to 455 K, The Journal of Chemical Thermodynamics, 1990, 22, 7, 617-622, https://doi.org/10.1016/0021-9614(90)90014-H . [all data]

López, Van Braak, et al., 1994
López, D.O.; Van Braak, J.; Tamarit, J.L.L.; Oonk, H.A.J., Thermodynamic phase diagram analysis of three binary systems shared by five neopentane derivatives, Calphad, 1994, 18, 4, 387-396, https://doi.org/10.1016/0364-5916(94)90016-7 . [all data]

Murrill and Breed, 1970, 2
Murrill, E.; Breed, L., Solid-solid phase transitions determined by differential scanning calorimetry, Thermochim. Acta, 1970, 1, 239-246. [all data]

Ardrey and Moffat, 1981
Ardrey, R.E.; Moffat, A.C., Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase, J. Chromatogr., 1981, 220, 3, 195-252, https://doi.org/10.1016/S0021-9673(00)81925-1 . [all data]

Notes

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• Symbols used in this document:
  

  Cp,solid	Constant pressure heat capacity of solid
  S°solid,1 bar	Entropy of solid at standard conditions (1 bar)
  Tboil	Boiling point
  Tfus	Fusion (melting) point
  Ttriple	Triple point temperature
  Ttrs	Temperature of phase transition
  ΔHtrs	Enthalpy of phase transition
  ΔStrs	Entropy of phase transition
  ΔcH°solid	Enthalpy of combustion of solid at standard conditions
  ΔfH°solid	Enthalpy of formation of solid at standard conditions
  ΔfusH	Enthalpy of fusion

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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