Sulfamethoxazole

• Formula: C₁₀H₁₁N₃O₃S
• Molecular weight: 253.278
• IUPAC Standard InChI: InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13) Copy

  
• IUPAC Standard InChIKey: JLKIGFTWXXRPMT-UHFFFAOYSA-N Copy
• CAS Registry Number: 723-46-6
• Chemical structure:
  This structure is also available as a 2d Mol file or as a computed 3d SD file
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• Other names: Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-; Bactrim; Gantanol; Metoxal; MS 53; N1-(5-Methyl-3-isoxazolyl)sulfanilamide; N'-(5-Methyl-3-isoxazole)sulfanilamide; N'-(5-Methyl-3-isoxazolyl)sulfanilamide; Radonil; Ro 4-2130; Ro 6-2580/11; Simsinomin; Sinomin; Sulfamethalazole; Sulfamethoxazol; Sulfamethylisoxazole; Sulfanilamide, N'-(5-methyl-3-isoxazolyl)-; Sulfanilamide, N1-(5-methyl-3-isoxazolyl)-; Sulfisomezole; Sulphamethoxazole; 3-Sulfanilamido-5-methylisoxazole; 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide; 5-Methyl-3-sulfonylamidoisoxazole; A047; 3-(para-Aminophenylsulphonamido)-5-methylisoxazole; Azo-gantanol; 5-Methyl-3-sulfanilamidoisoxazole; N'-(5-Methylisoxazol-3-yl)sulphanilamide; N¹-(5-Methyl-3-isoxazolyl)sulphanilamide; 5-Methyl-3-sulphanil-amidoisoxazole; Sulphamethoxazol; Sulpha-methoxizole; Sulphamethylisoxazole; 3-Sulphanilamido-5-methylisoxazole; Sulphisomezole; Sulfanilamide, ndimethyl1-(5-methyl-3-isoxazolyl)-; 3-(p-Aminobenzenesulfonamido)-5-methylisoxazole; Sulfanilamide, n^1-(5-methyl-3-isoxazolyl)-; 4-Amino-N-(5-methyl-3-isoxazolyl)benzene sulfonamide (sulfamethoxazole)
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• Information on this page:
  • Phase change data
  • References
  • Notes
• Other data available:
  • IR Spectrum
  • Mass spectrum (electron ionization)
  • Gas Chromatography
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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director
AC - William E. Acree, Jr., James S. Chickos

Enthalpy of fusion

References

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Sunwoo and Eisen, 1971
Sunwoo, C.; Eisen, H., Solubility parameter of selected sulfonamides, J. Pharm Sci., 1971, 60, 2, 238, https://doi.org/10.1002/jps.2600600217 . [all data]

Martínez, Ávila, et al., 2003
Martínez, Fleming; Ávila, Carolina M.; Gómez, Alfredo, Thermodynamic study of the solubility of some sulfonamides in cyclohexane, J. Braz. Chem. Soc., 2003, 14, 5, 803-808, https://doi.org/10.1590/S0103-50532003000500016 . [all data]

MartÍnez and GÓmez, 2002
MartÍnez, Fleming; GÓmez, Alfredo, Estimation of the Solubility of Sulfonamides in Aqueous Media from Partition Coefficients and Entropies of Fusion, Physics and Chemistry of Liquids, 2002, 40, 4, 411-420, https://doi.org/10.1080/0031910021000017735 . [all data]

Issa, El-Ansary, et al., 1998
Issa, Y.M.; El-Ansary, A.L.; Selim, W., Enthalpimetric Determination of Sulfa Drugs in Pure Form and Pharmaceutical Formulations, Analytical Letters, 1998, 31, 1, 131-146, https://doi.org/10.1080/00032719808001838 . [all data]

Notes

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• Symbols used in this document:
  

  Tfus	Fusion (melting) point
  ΔfusH	Enthalpy of fusion

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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