Mefenamic Acid


Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Quantity Value Units Method Reference Comment
Δsub32.6 ± 0.2kcal/molGSSurov, Terekhova, et al., 2009Based on data from 357. to 398. K.

Enthalpy of sublimation

ΔsubH (kcal/mol) Temperature (K) Method Reference Comment
31.7 ± 0.2377.GSSurov, Terekhova, et al., 2009Based on data from 357. to 398. K.

Enthalpy of fusion

ΔfusH (kcal/mol) Temperature (K) Method Reference
9.25503.5DSCSurov, Terekhova, et al., 2009
9.142503.6DSCRomero, Bustamante, et al., 2004
9.13503.6N/ARomero, 1999

Mass spectrum (electron ionization)

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Spectrum

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Additional Data

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Owner NIST Mass Spectrometry Data Center
Collection (C) 2014 copyright by the U.S. Secretary of Commerce
on behalf of the United States of America. All rights reserved.
Origin R.E.Ardrey ET AL.Pharmaceutical Mass Spectra,L.,1985
NIST MS number 298720

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References

Go To: Top, Phase change data, Mass spectrum (electron ionization), Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Surov, Terekhova, et al., 2009
Surov, Artem O.; Terekhova, Irina V.; Bauer-Brandl, Annette; Perlovich, German L., Thermodynamic and Structural Aspects of Some Fenamate Molecular Crystals, Crystal Growth & Design, 2009, 9, 7, 3265-3272, https://doi.org/10.1021/cg900002q . [all data]

Romero, Bustamante, et al., 2004
Romero, S.; Bustamante, P.; Escalera, B.; Cirri, M.; Mura, P., Characterization of the solid phases of paracetamol and fenamates at equilibrium in saturated solutions, Journal of Thermal Analysis and Calorimetry, 2004, 77, 2, 541-554, https://doi.org/10.1023/B:JTAN.0000038993.61782.ba . [all data]

Romero, 1999
Romero, S., Solubility behavior of polymorphs I and II of mefenamic acid in solvent mixtures, International Journal of Pharmaceutics, 1999, 178, 2, 193-202, https://doi.org/10.1016/S0378-5173(98)00375-5 . [all data]


Notes

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