Hydrochlorothiazide

• Formula: C₇H₈ClN₃O₄S₂
• Molecular weight: 297.739
• IUPAC Standard InChI: InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13) Copy

  
• IUPAC Standard InChIKey: JZUFKLXOESDKRF-UHFFFAOYSA-N Copy
• CAS Registry Number: 58-93-5
• Chemical structure:
  This structure is also available as a 2d Mol file
• Other names: 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide; Aquarills; Aquarius; Chlorosulthiadil; Dichlotiazid; Dichlotride; Diclotride; Dihydrochlorothiazid; Dihydrochlorothiazide; Dihydrochlorothiazidum; Disalunil; Drenol; Esidrex; Esidrix; Hidril; Hidrochlortiazid; Hidrotiazida; Hydril; Hydro-Aquil; Hydro-Diuril; Hydrochlorothiazid; Hydrochlorthiazide; Hydrodiuretic; Hydrosaluric; Hypothiazid; Hypothiazide; HCTZ; HCZ; Idrotiazide; Megadiuril; Nefrix; Oretic; Su 5879; Vetidrex; 3,4-Dihydrochlorothiazide; Dyazide; Jen-Diril; Maschitt; Newtolide; NCI-C55925; Servithiazid; Thiuretic; Thlaretic; 3,4-Dihydro-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide; 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; 6-Chloro-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide; 6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide; Bremil; Chlorsulfonamidodihydrobenzothiadiazine dioxide; Chlorzide; Cidrex; Dichlorosal; Direma; Fluvin; Hidroronol; Hydrothide; Ivaugan; Neo-codema; Neoflumen; Panurin; Ro-hydrazide; Thiaretic; Urodiazin; Zide; Hydrozide; Dihydrochlorurite; Dihydrochlorurit; Acuretic; Apresazide; Caplaril; H.H. 25/25; H.H. 50/50; Lopressor HCT; Lotensin HCT; Moduretic; Timolide; Unipres; Vaseretic; Ziac; 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide; 2H-1,2,4-Benzothiadiazine, 6-chloro-3,4-dihydro-7-sulfamoyl-2, 1,1-dioxide; Thiazide, hydrochloro-; 6-Chloro-7-sulfamoyl-3,4-dihydrobenzo-1,2,4-thiadiazine-1,1-dioxide; Carozide; Aquazide; Hydrocot; Hydrochlorzide; Urirex; Idrodiuvis; Microzide; Manschitt; H-1,2,4-benzothiadiazine, 6-chloro-3,4-dihydro-7-sulfamoyl-2, 1,1-dioxide; 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide (hydrochlorthiazide)
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• Information on this page:
  • Phase change data
  • References
  • Notes
• Other data available:
  • IR Spectrum
  • Mass spectrum (electron ionization)
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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Enthalpy of fusion

References

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Wassvik, Holmén, et al., 2006
Wassvik, Carola M.; Holmén, Anders G.; Bergström, Christel A.S.; Zamora, Ismael; Artursson, Per, Contribution of solid-state properties to the aqueous solubility of drugs, European Journal of Pharmaceutical Sciences, 2006, 29, 3-4, 294-305, https://doi.org/10.1016/j.ejps.2006.05.013 . [all data]

Hancock and Parks, 2000
Hancock, Bruno C.; Parks, Michael, Organometallics, 2000, 17, 4, 397-404, https://doi.org/10.1023/A:1007516718048 . [all data]

Notes

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• Symbols used in this document:
  

  ΔfusH

  Enthalpy of fusion

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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