Ethinyl Estradiol

• Formula: C₂₀H₂₄O₂
• Molecular weight: 296.4034
• IUPAC Standard InChI: InChI=1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m0/s1 Copy

  
• IUPAC Standard InChIKey: BFPYWIDHMRZLRN-CENDIDJXSA-N Copy
• CAS Registry Number: 57-63-6
• Chemical structure:
  This structure is also available as a 2d Mol file
• Other names: Ethynylestradiol; 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17α)-; Amenoron; Chee-O-Gen; Chee-O-Genf; Diogyn-E; Dyloform; Esteed; Estigyn; Estinyl; Eston-E; Estoral; Estorals; Estradiol, 17-ethynyl-; Ethidol; Ethinoral; Ethinyloestradiol; Eticyclin; Eticyclol; Etinestrol; Etinestryl; Etinoestryl; Etistradiol; Follicoral; Ginestrene; Inestra; Linoral; Lynoral; Menolyn; Neo-Estrone; Nogest-S; Novestrol; Oradiol; Orestralyn; Palonyl; Perovex; Primogyn; Primogyn C; Primogyn M; Progynon C; Spanestrin; 17α-Ethinyl-17β-estradiol; 17α-Ethinylestradiol; 17α-Ethynylestradiol; 17-Ethinyl-3,17-estradiol; 17-Ethinylestradiol; 17-Ethynylestradiol; Diognat-E; Ertonyl; Estoral (orion); Estra-1,3,5(10)-triene-3,17β-diol, 17α-ethynyl-; EE; Feminone; Ylestol; 17α-ethinyl-δ(sup1,3,5(10))oestratriene-3,17-β -diol; 17α-ethinyl-3,17-dihydroxy-δ(sup1,3,5)oestratriene; 17α-Ethinylestra-1,3,5(10)-triene-3,17β-diol; 17α-ethinyloestra-1,3,5(10)-triene-3,17β-diol; 17α-Ethinyl-3,17-dihydroxy-δ(sup1,3,5)-estratriene; 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol; 17α-Ethynyl-1,3,5(10)-oestratriene-3,17β-diol; 17α-Ethynyl-17β-oestradiol; 17α-Ethynylestra-1,3,5(10)-triene-3,17β-diol; 17α-Ethynylestradiol-l7β; 17α-Ethynyloestra-1,3,5(10)-triene-3,17β-diol; 17α-Ethynyloestradiol; 17α-Ethynyloestradiol-17β; 17-Ethinyl-3,17-oestradiol; 17-Ethynyl-3-17-dihydroxy-1,3,5-oestratriene; 17-Ethynyloestra-1,3,5(10)-triene-3,17β-diol; 17-Ethynyloestradiol; 19-nor-17α-Pregna-1,3,5(10)-trien-20-yne-3,17-diol; 3,17β-Dihydroxy-17α-ethynyl-1,3,5(10)-estratriene; 3,17β-Dihydroxy-17α-ethynyl-1,3,5(10)-oestratriene; 19-Nor-17α-pregna-1,3,5(10)-trien-20-yn-3,17-diol; Etivex; Kolpolyn; NSC-10973; Progynon M; Ethynyloestradiol; 17α-Ethinyl-1,3,5(10)-estratriene-3,17-diol; 19-Nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17β-diol; Prosexol; Ethinylestriol; component of Brevicon; component of Demulen; component of Estopherol; component of Gynetone; component of Halodrin; component of Modicon; component of Neocon; component of Norlestrin; component of Oracon; component of Ortrel; component of Ovcon; component of Ovral; component of Zorane; Anovlar; Estra-1,3,5(10)-triene-3,17β-diol, 17-ethynyl-; Estrogen; Eticylol; Orestrayln; Ovex; Ylestrol; 17α-Ethynyl-1,3,5-estratriene-3,17β-diol; 17α-Ethynyl-1,3,5-oestratriene-3,17β-diol; 17β-Estradiol, 17-ethynyl-; Thiuram E; Thiuranide; 17-Ethynylestradiol ram; component of Desogen; component of Estostep; component of Estrostep; Ethy 11; Gynolett; component of Levlen; component of Lo/ovral; component of Loestrin; component of Nolestrin; component of Nordette; component of Norethin 1/35e; component of Norethrin 1/35e; component of Ortho-cyclen; component of Ortho-novum; component of Tri-levlen; component of Triphasil; 17-Ethynylestra-1(10),2,4-triene-3,17-diol; 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol (ethinyl estradiol)
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• Information on this page:
  • Phase change data
  • Mass spectrum (electron ionization)
  • References
  • Notes
• Other data available:
  • Gas Chromatography
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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director
AC - William E. Acree, Jr., James S. Chickos

Enthalpy of fusion

Mass spectrum (electron ionization)

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Spectrum

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Additional Data

References

Go To: Top, Phase change data, Mass spectrum (electron ionization), Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Grady, Hays, et al., 1973
Grady, L.T.; Hays, S.E.; King, R.H.; Klein, H.R.; Mader, W.J.; Wyatt, D.K.; Zimmere, R.O., Drug purity profiles, J. Pharm. Sci., 1973, 62, 459. [all data]

van Laarhoven, Kruft, et al., 2002
van Laarhoven, J.A.H.; Kruft, M.A.B.; Vromans, H., In vitro release properties of etonogestrel and ethinyl estradiol from a contraceptive vaginal ring, International Journal of Pharmaceutics, 2002, 232, 1-2, 163-173, https://doi.org/10.1016/S0378-5173(01)00900-0 . [all data]

Notes

Go To: Top, Phase change data, Mass spectrum (electron ionization), References

• Symbols used in this document:
  

  Tfus	Fusion (melting) point
  ΔfusH	Enthalpy of fusion

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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