Serine

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Condensed phase thermochemistry data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein
DH - Eugene S. Domalski and Elizabeth D. Hearing

Quantity Value Units Method Reference Comment
Δfsolid-175.13 ± 0.067kcal/molCcbSabbah and Laffitte, 1978ALS
Quantity Value Units Method Reference Comment
Δcsolid-346.130 ± 0.043kcal/molCcbSabbah and Laffitte, 1978ALS
Quantity Value Units Method Reference Comment
solid,1 bar35.650cal/mol*KN/AHutchens, Cole, et al., 1964DH

Constant pressure heat capacity of solid

Cp,solid (cal/mol*K) Temperature (K) Reference Comment
33.20298.15Sabbah and Laffitte, 1978DH
32.400298.15Hutchens, Cole, et al., 1964T = 10 to 310 K.; DH

Reaction thermochemistry data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: John E. Bartmess

Note: Please consider using the reaction search for this species. This page allows searching of all reactions involving this species. A general reaction search form is also available. Future versions of this site may rely on reaction search pages in place of the enumerated reaction displays seen below.

Individual Reactions

L-Serine anion + Hydrogen cation = Serine

By formula: C3H6NO3- + H+ = C3H7NO3

Quantity Value Units Method Reference Comment
Δr332.5 ± 5.3kcal/molCIDCJones, Bernier, et al., 2007gas phase
Δr332.6 ± 3.1kcal/molG+TSO'Hair, Bowie, et al., 1992gas phase
Quantity Value Units Method Reference Comment
Δr325.8 ± 3.0kcal/molCIDCO'Hair, Bowie, et al., 1992gas phase

Gas phase ion energetics data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data evaluated as indicated in comments:
HL - Edward P. Hunter and Sharon G. Lias

Data compiled as indicated in comments:
B - John E. Bartmess
MM - Michael M. Meot-Ner (Mautner)

Quantity Value Units Method Reference Comment
Proton affinity (review)218.6kcal/molN/AHunter and Lias, 1998HL
Quantity Value Units Method Reference Comment
Gas basicity210.5kcal/molN/AHunter and Lias, 1998HL

Proton affinity at 298K

Proton affinity (kcal/mol) Reference Comment
216.2 ± 1.0Bouchoux and Salpin, 2003T = 298K; MM
218.1Bojesen and Breindahl, 1994PA increased by 0.9 kcal/mol for referencing values to Hunter and Lias, 1998; MM

Gas basicity at 298K

Gas basicity (review) (kcal/mol) Reference Comment
208.1 ± 1.0Bouchoux and Salpin, 2003T = 298K; MM

De-protonation reactions

L-Serine anion + Hydrogen cation = Serine

By formula: C3H6NO3- + H+ = C3H7NO3

Quantity Value Units Method Reference Comment
Δr332.5 ± 5.3kcal/molCIDCJones, Bernier, et al., 2007gas phase; B
Δr332.6 ± 3.1kcal/molG+TSO'Hair, Bowie, et al., 1992gas phase; B
Quantity Value Units Method Reference Comment
Δr325.8 ± 3.0kcal/molCIDCO'Hair, Bowie, et al., 1992gas phase; B

IR Spectrum

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: Coblentz Society, Inc.

Condensed Phase Spectrum

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IR spectrum
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Notice: Except where noted, spectra from this collection were measured on dispersive instruments, often in carefully selected solvents, and hence may differ in detail from measurements on FTIR instruments or in other chemical environments. More information on the manner in which spectra in this collection were collected can be found here.

Notice: Concentration information is not available for this spectrum and, therefore, molar absorptivity values cannot be derived.

Additional Data

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Owner COBLENTZ SOCIETY
Collection (C) 2018 copyright by the U.S. Secretary of Commerce
on behalf of the United States of America. All rights reserved.
Origin NCI FREDERICK CANCER RESEARCH INSTITUTE
Source reference COBLENTZ NO. 10283
Date 1974/05/24
Name(s) serine
L-PROPANOIC ACID, 2-AMINO-3-HYDROXY-
State SOLID (KBr DISC), CsI DISC FOR 400-50 CM-1
Instrument PERKIN-ELMER 180 (GRATING)
Instrument parameters FILTERS AT 2970, 2000, 1485, 1000, 743, 500, 372, 250, 186 AND GRATING CHANGES AT 2000, 1000, 500, 250 CM-1
Resolution 4
Sampling procedure TRANSMISSION
Data processing DIGITIZED BY NIST FROM HARD COPY (FROM TWO SEGMENTS)
Melting point SUBLIMES AT 150 C IN VACUUM, DECOMPOSES AT 228 C

This IR spectrum is from the Coblentz Society's evaluated infrared reference spectra collection.


Mass spectrum (electron ionization)

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Spectrum

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Mass spectrum
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Additional Data

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Due to licensing restrictions, this spectrum cannot be downloaded.

Owner NIST Mass Spectrometry Data Center
Collection (C) 2014 copyright by the U.S. Secretary of Commerce
on behalf of the United States of America. All rights reserved.
Origin Japan AIST/NIMC Database- Spectrum MS-NW-2507
NIST MS number 228085

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References

Go To: Top, Condensed phase thermochemistry data, Reaction thermochemistry data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Sabbah and Laffitte, 1978
Sabbah, R.; Laffitte, M., Enthalpy of formation of L-serine in the solid state, Thermochim. Acta, 1978, 23, 192-195. [all data]

Hutchens, Cole, et al., 1964
Hutchens, J.O.; Cole, A.G.; Stout, J.W., Heat capacities from 11 to 305 K, entropies, enthalpy, and free energy of formation of L-serine, J. Biol. Chem., 1964, 239, 4194-4195. [all data]

Jones, Bernier, et al., 2007
Jones, C.M.; Bernier, M.; Carson, E.; Colyer, K.E.; Metz, R.; Pawlow, A.; Wischow, E.D.; Webb, I.; Andriole, E.J.; Poutsma, J.C., Gas-phase Acities of the 20 Protein Amino Acids, Int. J. Mass Spectrom., 2007, 267, 1-3, 54-62, https://doi.org/10.1016/j.ijms.2007.02.018 . [all data]

O'Hair, Bowie, et al., 1992
O'Hair, R.J.; Bowie, J.H.; Gronert, S., Gas Phase Acidity of the alpha-Amino Acids, Int. J. Mass Spectrom. Ion Proc., 1992, 117, 23, https://doi.org/10.1016/0168-1176(92)80083-D . [all data]

Hunter and Lias, 1998
Hunter, E.P.; Lias, S.G., Evaluated Gas Phase Basicities and Proton Affinities of Molecules: An Update, J. Phys. Chem. Ref. Data, 1998, 27, 3, 413-656, https://doi.org/10.1063/1.556018 . [all data]

Bouchoux and Salpin, 2003
Bouchoux, G.; Salpin, J.Y., Gas-phase basicity of glycine, alanine, proline, serine, lysine, histidine and some of their peptides by the thermokinetic method, European J. Mass Spectrometry, 2003, 9, 391-402. [all data]

Bojesen and Breindahl, 1994
Bojesen, G.; Breindahl, T., On the Proton Affinity od Some Alpha-Amino Acids and the Theory of the Kinetic Method., J. Chem. Soc. Perkin 2, 1994, 1029. [all data]


Notes

Go To: Top, Condensed phase thermochemistry data, Reaction thermochemistry data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), References