3,24-Bis[(trimethylsilyl)oxy]cholest-5-ene, (3β,24R)-
- Formula: C33H62O2Si2
- Molecular weight: 547.0152
- IUPAC Standard InChI: InChI=1S/C33H62O2Si2/c1-23(2)31(35-37(9,10)11)17-12-24(3)28-15-16-29-27-14-13-25-22-26(34-36(6,7)8)18-20-32(25,4)30(27)19-21-33(28,29)5/h13,23-24,26-31H,12,14-22H2,1-11H3/t24?,26-,27?,28?,29?,30?,31?,32?,33?/m1/s1
- IUPAC Standard InChIKey: IDFZCXSXIWKWOC-ADHLUSNTSA-N
- CAS Registry Number: 55517-69-6
- Chemical structure:
This structure is also available as a 2d Mol file - Other names: Silane, [[(3β,24R)-cholest-5-ene-3,24-diyl]bis(oxy)]bis[trimethyl-; (24R)-Hydroxycholesterol, di-TMS; (24R)-Hydroxycholesterol, bis-TMS; 5-Cholesten-(3β,24R)-diol, bis-TMS; 5-Cholesten-3B(24R)-24-diol, TMS; 24-Hydroxycholesterol, TMS; 24-Hydroxycholesterol, di-TMS; 25-Hydroxycholesterol, di-TMS; 5-Cholesten-3B(24S)-24-diol, TMS
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Gas Chromatography
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
Kovats' RI, non-polar column, isothermal
| Column type | Active phase | Temperature (C) | I | Reference | Comment |
|---|---|---|---|---|---|
| Packed | OV-1 | 265. | 3390. | Gaskell, Smith, et al., 1975 | N2; Column length: 2. m |
| Packed | OV-1 | 265. | 3395. | Gaskell, Smith, et al., 1975 | N2; Column length: 2. m |
Normal alkane RI, non-polar column, custom temperature program
| Column type | Active phase | I | Reference | Comment |
|---|---|---|---|---|
| Capillary | Ultra-1 | 3385. | Axelson and Larsson, 1996 | 25. m/0.32 mm/0.17 μm; Program: 50C (3min) => (rapidly) => 185C => 5C/min => 280C |
References
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Gaskell, Smith, et al., 1975
Gaskell, S.J.; Smith, A.G.; Brooks, C.J.W.,
Gas chromatography mass spectrometry of trimethylsilyl ethers of sidechain hydroxylated Δ4-3-ketosteroids. Long range trimethylsilyl group migration under electron impact,
Biomed. Mass Spectrom., 1975, 2, 3, 148-155, https://doi.org/10.1002/bms.1200020309
. [all data]
Axelson and Larsson, 1996
Axelson, M.; Larsson, O.,
27-Hydroxylated low density lipoprotein (LDL) cholesterol can be converted to 7α,27-Dihydroxy-4-cholesten-3-one (cytosterone) before suppressing cholesterol production in normal human fibroblasts. Evidence that an altered metabolism of LDL cholesterol can underlie a defective feedback control in malignant cells,
J. Biol. Chem., 1996, 271, 22, 12724-12736. [all data]
Notes
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- Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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