Flufenamic acid

• Formula: C₁₄H₁₀F₃NO₂
• Molecular weight: 281.2299
• IUPAC Standard InChI: InChI=1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20) Copy

  
• IUPAC Standard InChIKey: LPEPZBJOKDYZAD-UHFFFAOYSA-N Copy
• CAS Registry Number: 530-78-9
• Chemical structure:
  This structure is also available as a 2d Mol file or as a computed 3d SD file
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• Other names: N-(3-Trifluoromethylphenyl)-anthranilic acid; Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-; Achless; Acido flufenamico; Anthranilic acid, N-(α,α,α-trifluoro-m-tolyl)-; Arlef; ANT-1; C.I. 440; CI 440; CN-27,554; Flufacid; Fluore-200; Fluphenamic acid; Fullsafe; INF 1837; Lanceat; N-(α,α,α-Trifluoro-m-tolyl)anthranilic acid; N-((m-Trifluoromethyl)phenyl)-2-aminobenzoic acid; Nichisedan; NSC-82699; Paraflu; Parlef; Parlif; Plostene; Reumajust A; Surika; Tecramine; TVX 916; 2-((3-Trifluromethyl)phenyl)aminobenzoic acid; 2-((3-(Trifluoromethyl)phenyl)amino)benzoic acid; 3'-Trifluoromethyldiphenylamine-2-carboxylic acid; Ansatin; Flufenaminsaeure; Meralen; Ristogen; Sastridex; CN-27544; NSC 219007; 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid (flufenamic acid)
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• Information on this page:
  • Phase change data
  • IR Spectrum
  • Mass spectrum (electron ionization)
  • Gas Chromatography
  • References
  • Notes
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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Enthalpy of sublimation

Enthalpy of fusion

IR Spectrum

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Gas Phase Spectrum

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Additional Data

Mass spectrum (electron ionization)

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Spectrum

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Additional Data

Gas Chromatography

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Kovats' RI, non-polar column, custom temperature program

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Van Den Dool and Kratz RI, non-polar column, custom temperature program

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Normal alkane RI, non-polar column, custom temperature program

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References

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Perlovich, Surov, et al., 2007
Perlovich, German L.; Surov, Artem O.; Bauer-Brandl, Annette, Thermodynamic properties of flufenamic and niflumic acids---Specific and non-specific interactions in solution and in crystal lattices, mechanism of solvation, partitioning and distribution, Journal of Pharmaceutical and Biomedical Analysis, 2007, 45, 4, 679-687, https://doi.org/10.1016/j.jpba.2007.01.039 . [all data]

Surov, Terekhova, et al., 2009
Surov, Artem O.; Terekhova, Irina V.; Bauer-Brandl, Annette; Perlovich, German L., Thermodynamic and Structural Aspects of Some Fenamate Molecular Crystals, Crystal Growth & Design, 2009, 9, 7, 3265-3272, https://doi.org/10.1021/cg900002q . [all data]

Romero, Bustamante, et al., 2004
Romero, S.; Bustamante, P.; Escalera, B.; Cirri, M.; Mura, P., Characterization of the solid phases of paracetamol and fenamates at equilibrium in saturated solutions, Journal of Thermal Analysis and Calorimetry, 2004, 77, 2, 541-554, https://doi.org/10.1023/B:JTAN.0000038993.61782.ba . [all data]

McLinden and Stenhouse, 1979
McLinden, V.J.; Stenhouse, A.M., A chromatography system for drug identification, Forensic Sci. Int., 1979, 13, 71-79, https://doi.org/10.1016/0379-0738(79)90265-2 . [all data]

Stowell and Wilson, 1987
Stowell, A.; Wilson, L.W., A simple approach to the interlaboratory transfer of drug retention indices determined by temperature programmed capillary gas chromatography, J. Forensic Sci., 1987, 32, 5, 1214-1220. [all data]

Ardrey and Moffat, 1981
Ardrey, R.E.; Moffat, A.C., Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase, J. Chromatogr., 1981, 220, 3, 195-252, https://doi.org/10.1016/S0021-9673(00)81925-1 . [all data]

Notes

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• Symbols used in this document:
  

  ΔfusH	Enthalpy of fusion
  ΔsubH	Enthalpy of sublimation
  ΔsubH°	Enthalpy of sublimation at standard conditions
  ΔvapH°	Enthalpy of vaporization at standard conditions

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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