Aspirin

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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director
AC - William E. Acree, Jr., James S. Chickos

Quantity Value Units Method Reference Comment
Tfus405. ± 10.KAVGN/AAverage of 103 out of 110 values; Individual data points

Enthalpy of fusion

ΔfusH (kcal/mol) Temperature (K) Method Reference Comment
6.972409.2DSCXu, Sun, et al., 2004AC
7.412412.7DSCPerlovich and Bauer-Brandl, 2001See also Perlovich and Bauer-Brandl, 2003.; AC
7.12414.N/AKirklin, 2000AC

In addition to the Thermodynamics Research Center (TRC) data available from this site, much more physical and chemical property data is available from the following TRC products:

Gas Chromatography

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Kovats' RI, non-polar column, isothermal

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Column type Active phase Temperature (C) I Reference Comment
CapillaryDB-1130.1270.Japp, Gill, et al., 198730. m/0.53 mm/1.5 μm, N2
PackedOV-1150.1315.Berninger and Möller, 1977 

Normal alkane RI, non-polar column, custom temperature program

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Column type Active phase I Reference Comment
CapillaryPolydimethyl siloxanes1309.Schutz and Wollrab A., 1988Program: not specified
OtherMethyl Silicone1309.Ardrey and Moffat, 1981Program: not specified

References

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Xu, Sun, et al., 2004
Xu, F.; Sun, L.-X.; Tan, Z.-C.; Liang, J.-G.; Zhou, D.-H.; Di, Y.-Y.; Lan, X.Z.; Zhang, T., Wuji Huaxue Xuebao, 2004, 20, 1, 50. [all data]

Perlovich and Bauer-Brandl, 2001
Perlovich, G.L.; Bauer-Brandl, A., Organometallics, 2001, 63, 3, 653-661, https://doi.org/10.1023/A:1010119532614 . [all data]

Perlovich and Bauer-Brandl, 2003
Perlovich, German L.; Bauer-Brandl, Annette, Pharmaceutical Research, 2003, 20, 3, 471-478, https://doi.org/10.1023/A:1022624725495 . [all data]

Kirklin, 2000
Kirklin, Duane R., Enthalpy of combustion of acetylsalicylic acid, The Journal of Chemical Thermodynamics, 2000, 32, 6, 701-709, https://doi.org/10.1006/jcht.1999.0650 . [all data]

Japp, Gill, et al., 1987
Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 1987, 32, 6, 1574-1586. [all data]

Berninger and Möller, 1977
Berninger, H.; Möller, M.R., Retentionsindices zur gaschromatographischen Identifizierung von Arzneimitteln, Arch. Toxicol., 1977, 37, 4, 295-305, https://doi.org/10.1007/BF00330821 . [all data]

Schutz and Wollrab A., 1988
Schutz, H.; Wollrab A., The significance of the retention index in toxicologic analysis II, Pharmazie in unzerer Zeit, 1988, 17, 4, 97-101. [all data]

Ardrey and Moffat, 1981
Ardrey, R.E.; Moffat, A.C., Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase, J. Chromatogr., 1981, 220, 3, 195-252, https://doi.org/10.1016/S0021-9673(00)81925-1 . [all data]

Notes

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