Niclosamide

• Formula: C₁₃H₈Cl₂N₂O₄
• Molecular weight: 327.120
• IUPAC Standard InChI: InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19) Copy

  
• IUPAC Standard InChIKey: RJMUSRYZPJIFPJ-UHFFFAOYSA-N Copy
• CAS Registry Number: 50-65-7
• Chemical structure:
  This structure is also available as a 2d Mol file
• Other names: Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-; Salicylanilide, 2',5-dichloro-4'-nitro-; Bayer 2353; Bayluscid; BAY 2353; Cestocid; Devermin; Devermine; Fedal-Telmin; Fenasal; Helmiantin; HL 2447; Iomesan; Lintex; Mansonil; Mato; Nasemo; Phenasal; Radeverm; Sagimid; Sulqui; Tredemine; Vermitid; Vermitin; Yomesan; 2',5-Dichloro-4'-Nitrosalicylanilide; Atenase; Bayer 73; Dichlosale; Iomezan; N-(2-Chloro-4-nitrophenyl)-5-chlorosalicylamide; N-(2'-Chloro-4'-nitrophenyl)-5-chlorosalicylamide; 2-Chloro-4-nitrophenylamide-6-chlorosalicylic acid; 2-Hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide; 2',5-Dichlor-4'-nitro-salizylsaeureanilid; 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide; 5-Chloro-2'-chloro-4'-nitrosalicylanilide; Chemagro 2353; N-(2'-Chlor-4'-nitrophenyl)-5-chlorsalicylamid; ENT 25823; Niclocide; Cestocide; Ruby; 5-Chloro-N-(2'-chloro-4'-nitrophenyl)salicylamide; WR 46234; Zestocarp; 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (niclosamide)
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• Information on this page:
  • Phase change data
  • References
  • Notes
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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Enthalpy of fusion

References

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Yang and de Villiers, 2005
Yang, Wenzhan; de Villiers, Melgardt M., Effect of 4-sulphonato-calix[n]arenes and cyclodextrins on the solubilization of niclosamide, a poorly water soluble anthelmintic, AAPS J, 2005, 7, 1, E241-E248, https://doi.org/10.1208/aapsj070123 . [all data]

van Tonder, Maleka, et al., 2004
van Tonder, Elsa C.; Maleka, Tshoane S.P.; Liebenberg, Wilna; Song, Mingna; Wurster, Dale Eric; de Villiers, Melgardt M., Preparation and physicochemical properties of niclosamide anhydrate and two monohydrates, International Journal of Pharmaceutics, 2004, 269, 2, 417-432, https://doi.org/10.1016/j.ijpharm.2003.09.035 . [all data]

Notes

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• Symbols used in this document:
  

  ΔfusH

  Enthalpy of fusion

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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