Hydrocortisone

• Formula: C₂₁H₃₀O₅
• Molecular weight: 362.4599
• IUPAC Standard InChI: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m1/s1 Copy

  
• IUPAC Standard InChIKey: JYGXADMDTFJGBT-NDNUHCHRSA-N Copy
• CAS Registry Number: 50-23-7
• Chemical structure:
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• Stereoisomers:
  • 11Beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione
• Other names: Hydroxycortisone; Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11β)-; Cortisol; anti-Inflammatory hormone; Cobadex; Cort-Dome; Cortanal; Cortef; Cortenema; Corticreme; Cortifan; Cortiment; Cortispray; Cortonema; Cortril; Dihydrocostisone; Domolene-HC; Efcorbin; Epiderm H; Esiderm H; Ficortril; Genacort; Heb-Cort; Hidro-Colisona; Hycort; Hycortol; Hycortole; Hydrasson; Hydro-Adreson; Hydrocorticosterone; Hydrocortisone alcohol; Hydrocortisyl; Hydrocortone; Hytone lotion; HC; Incortin-H; Kendall's Compound F; NSC 10483; Optef; Otosone-F; Permicort; Polcort H; Reichstein's Substance M; Scheroson F; Signef; Tarcortin; Texacort lotion 25; Topicort; Traumaide; 11β-Hydroxycortisone; 17α-Hydroxycorticosterone; 17-Hydroxycorticosterone; 4-Pregnen-11β,17α,21-triol-3,20-dione; Aeroseb HC; Ala-Scalp; Alacort; Barseb HC; Cetacort; Cleiton; Compound F; Compound F (kendall); Cortisol alcohol; Cortolotion; Cortoxide; Cremesone; Delacort; Dermacort; Dermolate; Efcortelan; Efcortelin; Eldecort; Eldercort; Epicort; Fiocortril; H-Cort; Hydro-colisona; Hydrocortisone free alcohol; Hydrocortistab; Hytone; Incortin-hydrogen; Komed HC; Maintasone; Pregn-4-ene-3,20-dione, 11β,17,21-trihydroxy-; Proctocort; Rectoid; 11β-Hydrocortisone; 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione; 11β,17,21-Trihydroxypregn-4-ene-3,20-dione; 4-Pregnene-11β,17α,21-triol-3,20-dione; Acticort; CaldeCort Spray; Lacticare-HC; Nutracort; Penecort; 11,17,21-Trihydroxypregn-4-ene-3,20-dione, (11β)-; 11β,17,21-trihydroxyprogesterone; Dioderm; Anflam; Dermocortal; Zenoxone; U 1851; Medicort; Mildison; 11Beta,17,21-trihydroxy progesterone; Cor-Tar-Quin (Salt/Mix); Cort-Quin (Salt/Mix); Cortisporin (Salt/Mix); Drotic (Salt/Mix); Neo-Cort-Dome (Salt/Mix); Nystaform-HC (Salt/Mix); Otalgine (Salt/Mix); Otic-Neo-Cort-Dome (Salt/Mix); Otobiotic (Salt/Mix); Otocort (Salt/Mix); Pediotic Suspension (Salt/Mix); Racet (Salt/Mix); Vioform-Hydrocortisone (Salt/Mix); VoSol HC (Salt/Mix); Vytone (Salt/Mix); Alphaderm (Salt/Mix)
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• Information on this page:
  • Condensed phase thermochemistry data
  • Phase change data
  • References
  • Notes
• Other data available:
  • IR Spectrum
  • Mass spectrum (electron ionization)
  • UV/Visible spectrum
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Condensed phase thermochemistry data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein

Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Enthalpy of fusion

References

Go To: Top, Condensed phase thermochemistry data, Phase change data, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Paoli, Garrigues, et al., 1969
Paoli, D.; Garrigues, J.-C.; Patin, H., Combustion microcalorimetry: application to steroids, C. R. Acad. Sci. Paris, 1969, 268, 780-783. [all data]

Regosz, Chmielewska, et al., 1994
Regosz, A.; Chmielewska, A.; Pelplinska, T.; Kowalski, P., Prediction of the solubility of steroid hormones, Pharmazie, 1994, 49, 5, 371. [all data]

Notes

Go To: Top, Condensed phase thermochemistry data, Phase change data, References

• Symbols used in this document:
  

  ΔcH°solid	Enthalpy of combustion of solid at standard conditions
  ΔfusH	Enthalpy of fusion

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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