Fenbufen


Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Quantity Value Units Method Reference Comment
Δsub37.0 ± 0.2kcal/molGSKurkov and Perlovich, 2008Based on data from 378. to 420. K.

Enthalpy of fusion

ΔfusH (kcal/mol) Temperature (K) Method Reference
9.82462.9DSCKurkov and Perlovich, 2008
11.0459.3DSCWassvik, Holmén, et al., 2006

References

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Kurkov and Perlovich, 2008
Kurkov, Sergey V.; Perlovich, German L., Thermodynamic studies of Fenbufen, Diflunisal, and Flurbiprofen: Sublimation, solution and solvation of biphenyl substituted drugs, International Journal of Pharmaceutics, 2008, 357, 1-2, 100-107, https://doi.org/10.1016/j.ijpharm.2008.01.059 . [all data]

Wassvik, Holmén, et al., 2006
Wassvik, Carola M.; Holmén, Anders G.; Bergström, Christel A.S.; Zamora, Ismael; Artursson, Per, Contribution of solid-state properties to the aqueous solubility of drugs, European Journal of Pharmaceutical Sciences, 2006, 29, 3-4, 294-305, https://doi.org/10.1016/j.ejps.2006.05.013 . [all data]


Notes

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