Piroxicam

• Formula: C₁₅H₁₃N₃O₄S
• Molecular weight: 331.346
• IUPAC Standard InChI: InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20) Copy

  
• IUPAC Standard InChIKey: QYSPLQLAKJAUJT-UHFFFAOYSA-N Copy
• CAS Registry Number: 36322-90-4
• Chemical structure:
  This structure is also available as a 2d Mol file or as a computed 3d SD file
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• Other names: 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide; CP 16171; Feldene; 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid; 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide; 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide1,1-dioxide; Artroxicam; Baxo; Bruxicam; Caliment; Erazon; Flogobene; Geldene; Improntal; Larapam; Pirkam; Piroflex; Reudene; Riacen; Roxicam; Roxiden; Sasulen; Solocalm; Zunden; CHF 1251; NSC 666076; Piroftal; Pyroxycam; 2H-1,2-benzothiazine-3-carboxyamide-4-hydroxy-2-methyl-N-2-pyridinyl-1,1-dioxide (piroxicam)
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• Information on this page:
  • Phase change data
  • Mass spectrum (electron ionization)
  • References
  • Notes
• Other data available:
  • Gas Chromatography
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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Enthalpy of fusion

Mass spectrum (electron ionization)

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Spectrum

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Additional Data

References

Go To: Top, Phase change data, Mass spectrum (electron ionization), Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Drebushchak1, Shakhtshneider, et al., 2006
Drebushchak1, V.A.; Shakhtshneider, T.P.; Apenina, S.A.; Drebushchak, T.N.; Medvedeva, A.S.; Safronova, L.P.; Boldyrev, V.V., Thermoanalytical investigation of drug-excipient interaction, J Therm Anal Calorim, 2006, 84, 3, 643-649, https://doi.org/10.1007/s10973-005-9990-4 . [all data]

Wassvik, Holmén, et al., 2006
Wassvik, Carola M.; Holmén, Anders G.; Bergström, Christel A.S.; Zamora, Ismael; Artursson, Per, Contribution of solid-state properties to the aqueous solubility of drugs, European Journal of Pharmaceutical Sciences, 2006, 29, 3-4, 294-305, https://doi.org/10.1016/j.ejps.2006.05.013 . [all data]

Wassvik, Holmén, et al., 2008
Wassvik, Carola M.; Holmén, Anders G.; Draheim, Rieke; Artursson, Per; Bergström, Christel A.S., Molecular Characteristics for Solid-State Limited Solubility, J. Med. Chem., 2008, 51, 10, 3035-3039, https://doi.org/10.1021/jm701587d . [all data]

Bustamante, Peña, et al., 1998
Bustamante, P.; Peña, M.A.; Barra, J., Partial solubility parameters of piroxicam and niflumic acid, International Journal of Pharmaceutics, 1998, 174, 1-2, 141-150, https://doi.org/10.1016/S0378-5173(98)00263-4 . [all data]

Giordano, Gazzaniga, et al., 1998
Giordano, Ferdinando; Gazzaniga, Andrea; Moyano, Jos«65533» Ramon; Ventura, Paolo; Zanol, Margherita; Peveri, Tiziana; Carima, Lorenza, Crystal forms of piroxicam pivalate: Preparation and characterization of two polymorphs, J. Pharm. Sci., 1998, 87, 3, 333-337, https://doi.org/10.1021/js970256b . [all data]

Notes

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• Symbols used in this document:
  

  ΔfusH

  Enthalpy of fusion

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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