Piroxicam


Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Enthalpy of fusion

ΔfusH (kJ/mol) Temperature (K) Method Reference Comment
35.473.9DSCDrebushchak1, Shakhtshneider, et al., 2006 
36.3473.4DSCWassvik, Holmén, et al., 2006See also Wassvik, Holmén, et al., 2008.
34.5473.DSCBustamante, Peña, et al., 1998 
35.474.5N/AGiordano, Gazzaniga, et al., 1998 

Mass spectrum (electron ionization)

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Spectrum

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Mass spectrum
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Additional Data

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Owner NIST Mass Spectrometry Data Center
Collection (C) 2014 copyright by the U.S. Secretary of Commerce
on behalf of the United States of America. All rights reserved.
Origin R.E.Ardrey ET AL.Pharmaceutical Mass Spectra,L.,1985
NIST MS number 298765

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Gas Chromatography

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Normal alkane RI, non-polar column, temperature ramp

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Column type Active phase I Reference Comment
CapillaryDB-11413.Sharp, 198715. m/0.25 mm/0.25 μm, He, 130. C @ 1. min, 10. K/min, 290. C @ 10. min

References

Go To: Top, Phase change data, Mass spectrum (electron ionization), Gas Chromatography, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Drebushchak1, Shakhtshneider, et al., 2006
Drebushchak1, V.A.; Shakhtshneider, T.P.; Apenina, S.A.; Drebushchak, T.N.; Medvedeva, A.S.; Safronova, L.P.; Boldyrev, V.V., Thermoanalytical investigation of drug-excipient interaction, J Therm Anal Calorim, 2006, 84, 3, 643-649, https://doi.org/10.1007/s10973-005-9990-4 . [all data]

Wassvik, Holmén, et al., 2006
Wassvik, Carola M.; Holmén, Anders G.; Bergström, Christel A.S.; Zamora, Ismael; Artursson, Per, Contribution of solid-state properties to the aqueous solubility of drugs, European Journal of Pharmaceutical Sciences, 2006, 29, 3-4, 294-305, https://doi.org/10.1016/j.ejps.2006.05.013 . [all data]

Wassvik, Holmén, et al., 2008
Wassvik, Carola M.; Holmén, Anders G.; Draheim, Rieke; Artursson, Per; Bergström, Christel A.S., Molecular Characteristics for Solid-State Limited Solubility, J. Med. Chem., 2008, 51, 10, 3035-3039, https://doi.org/10.1021/jm701587d . [all data]

Bustamante, Peña, et al., 1998
Bustamante, P.; Peña, M.A.; Barra, J., Partial solubility parameters of piroxicam and niflumic acid, International Journal of Pharmaceutics, 1998, 174, 1-2, 141-150, https://doi.org/10.1016/S0378-5173(98)00263-4 . [all data]

Giordano, Gazzaniga, et al., 1998
Giordano, Ferdinando; Gazzaniga, Andrea; Moyano, Jos«65533» Ramon; Ventura, Paolo; Zanol, Margherita; Peveri, Tiziana; Carima, Lorenza, Crystal forms of piroxicam pivalate: Preparation and characterization of two polymorphs, J. Pharm. Sci., 1998, 87, 3, 333-337, https://doi.org/10.1021/js970256b . [all data]

Sharp, 1987
Sharp, M.E., A rapid screening procedure for acidic and neutral drugs in blood by high resolution gas chromatography, J. Anal. Toxicol., 1987, 11, 1, 8-11, https://doi.org/10.1093/jat/11.1.8 . [all data]


Notes

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