1,4-Dithiothreitol
- Formula: C4H10O2S2
- Molecular weight: 154.251
- IUPAC Standard InChI: InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2
- IUPAC Standard InChIKey: VHJLVAABSRFDPM-UHFFFAOYSA-N
- CAS Registry Number: 3483-12-3
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Other names: Dithiothreitol; 1,4-Dithio-dl-threitol; dl-Dithiothreitol; 2,3-Butanediol, 1,4-dimercapto-, (R*,R*)-(.+/-.)-; Threitol, 1,4-dithio-, dl-; 2,3-Butanediol, 1,4-dimercapto-, dl, threo-; Cleland's reagent; DL-threo-1,4-Dimercapto-2,3-butanediol; DL-1,4-Dithiothreitol; rac-Dithiothreitol; DTT; 1,4-Disulfanyl-2,3-butanediol, dl, threo-; (.+/-.)-Dithiothreitol; 2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel-; Sputolysin; Threitol, 1,4-dithio-; WR 34678; (R*,R*)-1,4-dimercaptobutane-2,3-diol; 2,3-Butanediol, 1,4-dimercapto-, (r*,r*)-
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Reaction thermochemistry data
Go To: Top, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein
Note: Please consider using the reaction search for this species. This page allows searching of all reactions involving this species. A general reaction search form is also available. Future versions of this site may rely on reaction search pages in place of the enumerated reaction displays seen below.
Individual Reactions
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By formula: C4H10O2S2 = H2 + C8H18O4S4
| Quantity | Value | Units | Method | Reference | Comment |
|---|---|---|---|---|---|
| ΔrH° | -7.53 ± 0.62 | kcal/mol | Cm | Fukada and Takahashi, 1980 | liquid phase; solvent: Buffers pH 6-13; Redox reaction with K3Fe(CN)6 |
References
Go To: Top, Reaction thermochemistry data, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Fukada and Takahashi, 1980
Fukada, H.; Takahashi, K.,
Calorimetric study of the oxidation of dithiothreitol,
J. Biochem., 1980, 87, 1105-1110. [all data]
Notes
Go To: Top, Reaction thermochemistry data, References
- Symbols used in this document:
ΔrH° Enthalpy of reaction at standard conditions - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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