Atenolol
- Formula: C14H22N2O3
- Molecular weight: 266.3361
- IUPAC Standard InChI: InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
- IUPAC Standard InChIKey: METKIMKYRPQLGS-UHFFFAOYSA-N
- CAS Registry Number: 29122-68-7
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Other names: Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-; Acetamide, 2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)-; 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol; 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide; 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide; ICI 66082; Normiten; Tenormin; Atehexal; Atenol; Cuxanorm; Ibinolo; Myocord; Prenormine; Seles beta; Selobloc; Teno-basan; Tenoblock; Uniloc; 2-(4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl)acetamide; Alinor; Altol; Anselol; Antipressan; Apo-Atenolol; Atcardil; Atecard; Atenblock; Atendol; Atenet; Ateni; Atenil; Atereal; Aterol; Betablok; Betacard; Blokium; Corotenol; Duraatenolol; Evitocor; Farnormin; Felo-Bits; Hipres; Hypoten; Internolol; Lo-ten; Lotenal; Normalol; Noten; Oraday; Premorine; Prenolol; Serten; Stermin; Tenidon; Tenolol; Tenoprin; Tenormine; Tensimin; Tredol; Vascoten; Vericordin; Wesipin; Xaten; Tenoretic (Salt/Mix); (+) 4-[2'-Hydroxy-3'-(isopropylamino)propoxy]-phenylacetamide (atenolol)
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Phase change data
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: William E. Acree, Jr., James S. Chickos
| Quantity | Value | Units | Method | Reference | Comment |
|---|---|---|---|---|---|
| ΔsubH° | 140.0 ± 3.7 | kJ/mol | GS | Perlovich, Volkova, et al., 2007 | Based on data from 396. to 418. K. |
Enthalpy of fusion
| ΔfusH (kJ/mol) | Temperature (K) | Method | Reference |
|---|---|---|---|
| 38.7 | 426.1 | DSC | Perlovich, Volkova, et al., 2007 |
| 35.66 | 423.4 | DSC | Li, Zell, et al., 1999 |
References
Go To: Top, Phase change data, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Perlovich, Volkova, et al., 2007
Perlovich, German L.; Volkova, Tatyana V.; Bauer-Brandl, Annette,
Thermodynamic Study of Sublimation, Solubility, Solvation, and Distribution Processes of Atenolol and Pindolol,
Mol. Pharmaceutics, 2007, 4, 6, 929-935, https://doi.org/10.1021/mp070039b
. [all data]
Li, Zell, et al., 1999
Li, Z. Jane; Zell, Mark T.; Munson, Eric J.; Grant, David J.W.,
Characterization of racemic species of chiral drugs using thermal analysis, thermodynamic calculation, and structural studies,
J. Pharm. Sci., 1999, 88, 3, 337-346, https://doi.org/10.1021/js980205u
. [all data]
Notes
Go To: Top, Phase change data, References
- Symbols used in this document:
ΔfusH Enthalpy of fusion ΔsubH° Enthalpy of sublimation at standard conditions - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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