Naproxen

Data at NIST subscription sites:

NIST subscription sites provide data under the NIST Standard Reference Data Program, but require an annual fee to access. The purpose of the fee is to recover costs associated with the development of data collections included in such sites. Your institution may already be a subscriber. Follow the links above to find out more about the data in these sites and their terms of usage.


Phase change data

Go To: Top, References, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Enthalpy of sublimation

ΔsubH (kJ/mol) Temperature (K) Method Reference
128.3 ± 0.5341. to 397.GSPerlovich, Kurkov, et al., 2004

Enthalpy of fusion

ΔfusH (kJ/mol) Temperature (K) Method Reference
34.2428.8DSCWassvik, Holmén, et al., 2006
31.5428.5N/ANeau, Bhandarkar, et al., 1997
29.41439.2N/AClaramonte, Vialard, et al., 1993

References

Go To: Top, Phase change data, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Perlovich, Kurkov, et al., 2004
Perlovich, German L.; Kurkov, Sergey V.; Kinchin, Andrey N.; Bauer-Brandl, Annette, Thermodynamics of solutions III: comparison of the solvation of (+)-naproxen with other NSAIDs, European Journal of Pharmaceutics and Biopharmaceutics, 2004, 57, 2, 411-420, https://doi.org/10.1016/j.ejpb.2003.10.021 . [all data]

Wassvik, Holmén, et al., 2006
Wassvik, Carola M.; Holmén, Anders G.; Bergström, Christel A.S.; Zamora, Ismael; Artursson, Per, Contribution of solid-state properties to the aqueous solubility of drugs, European Journal of Pharmaceutical Sciences, 2006, 29, 3-4, 294-305, https://doi.org/10.1016/j.ejps.2006.05.013 . [all data]

Neau, Bhandarkar, et al., 1997
Neau, Steven H.; Bhandarkar, Satej V.; Hellmuth, Eckhard W., Pharmaceutical Research, 1997, 14, 5, 601-605, https://doi.org/10.1023/A:1012148910975 . [all data]

Claramonte, Vialard, et al., 1993
Claramonte, M.D. Contreras; Vialard, A. Parera; Vilchez, F. Girela, An application of regular solution theory in the study of the solubility of naproxen in some solvents used in topical preparations, International Journal of Pharmaceutics, 1993, 94, 1-3, 23-30, https://doi.org/10.1016/0378-5173(93)90005-Z . [all data]


Notes

Go To: Top, Phase change data, References