Diclofenac


Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Quantity Value Units Method Reference Comment
Δsub27.63 ± 0.31kcal/molGSPerlovich, Surov, et al., 2007Based on data from 323. to 355. K. See also Surov, Terekhova, et al., 2009.

Enthalpy of sublimation

ΔsubH (kcal/mol) Temperature (K) Method Reference Comment
27.41 ± 0.31339.GSPerlovich, Surov, et al., 2007Based on data from 323. to 355. K. See also Surov, Terekhova, et al., 2009.

Enthalpy of fusion

ΔfusH (kcal/mol) Temperature (K) Method Reference
9.66452.6DSCSurov, Terekhova, et al., 2009
9.42454.2DSCPasquali, Bettini, et al., 2007

Mass spectrum (electron ionization)

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Spectrum

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Owner NIST Mass Spectrometry Data Center
Collection (C) 2014 copyright by the U.S. Secretary of Commerce
on behalf of the United States of America. All rights reserved.
Origin Drug Lab
NIST MS number 379262

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References

Go To: Top, Phase change data, Mass spectrum (electron ionization), Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Perlovich, Surov, et al., 2007
Perlovich, German L.; Surov, Artem O.; Hansen, Lars Kr.; Bauer-Brandl, Annette, Energetic aspects of diclofenac acid in crystal modifications and in solutions---mechanism of solvation, partitioning and distribution, J. Pharm. Sci., 2007, 96, 5, 1031-1042, https://doi.org/10.1002/jps.20936 . [all data]

Surov, Terekhova, et al., 2009
Surov, Artem O.; Terekhova, Irina V.; Bauer-Brandl, Annette; Perlovich, German L., Thermodynamic and Structural Aspects of Some Fenamate Molecular Crystals, Crystal Growth & Design, 2009, 9, 7, 3265-3272, https://doi.org/10.1021/cg900002q . [all data]

Pasquali, Bettini, et al., 2007
Pasquali, Irene; Bettini, R.; Giordano, F., Thermal behaviour of diclofenac, diclofenac sodium and sodium bicarbonate compositions, J Therm Anal Calorim, 2007, 90, 3, 903-907, https://doi.org/10.1007/s10973-006-8182-1 . [all data]


Notes

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