Mefenamic Acid
- Formula: C15H15NO2
- Molecular weight: 241.2851
- IUPAC Standard InChI: InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)
- IUPAC Standard InChIKey: HYYBABOKPJLUIN-UHFFFAOYSA-N
- CAS Registry Number: 61-68-7
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Other names: Benzoic acid, 2-[(2,3-dimethylphenyl)amino]-; Anthranilic acid, N-2,3-xylyl-; AGN-1255; Bafameritin-M; Bonabol; Coslan; CL 473; CN-35355; HL 1; INF 3355; Lysalgo; Mefacit; Mephenamic acid; Mephenaminic acid; Methenamic acid; N-(2,3-Dimethylphenyl)anthranilic acid; N-(2,3-Xylyl)-2-aminobenzoic acid; N-(2,3-Xylyl)anthranilic acid; Parkemed; Ponalar; Ponstan; Ponstel; Ponstil; Ponstyl; Pontal; Tamany Bonsan; Tanston; Vialidon; 2-((2,3-Dimethylphenyl)amino)benzoic acid; 2-Diphenylaminecarboxylic acid, 2',3'-dimethyl-; Acide mefenamique; Bafhameritin-M; Mefenaminsaeure; Namphen; Ponstan forte; In-M; Mefanamic acid; Mefenacid; NSC 94437; 2-[(2,3-Dimethylphenyl)amino]benzoic acid (mefenamic acid)
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Phase change data
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: William E. Acree, Jr., James S. Chickos
| Quantity | Value | Units | Method | Reference | Comment |
|---|---|---|---|---|---|
| ΔsubH° | 136.3 ± 0.8 | kJ/mol | GS | Surov, Terekhova, et al., 2009 | Based on data from 357. - 398. K. |
Enthalpy of sublimation
| ΔsubH (kJ/mol) | Temperature (K) | Method | Reference | Comment |
|---|---|---|---|---|
| 132.7 ± 0.8 | 377. | GS | Surov, Terekhova, et al., 2009 | Based on data from 357. - 398. K. |
Enthalpy of fusion
| ΔfusH (kJ/mol) | Temperature (K) | Method | Reference |
|---|---|---|---|
| 38.7 | 503.5 | DSC | Surov, Terekhova, et al., 2009 |
| 38.25 | 503.6 | DSC | Romero, Bustamante, et al., 2004 |
| 38.2 | 503.6 | N/A | Romero, 1999 |
References
Go To: Top, Phase change data, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Surov, Terekhova, et al., 2009
Surov, Artem O.; Terekhova, Irina V.; Bauer-Brandl, Annette; Perlovich, German L.,
Thermodynamic and Structural Aspects of Some Fenamate Molecular Crystals,
Crystal Growth & Design, 2009, 9, 7, 3265-3272, https://doi.org/10.1021/cg900002q
. [all data]
Romero, Bustamante, et al., 2004
Romero, S.; Bustamante, P.; Escalera, B.; Cirri, M.; Mura, P.,
Characterization of the solid phases of paracetamol and fenamates at equilibrium in saturated solutions,
Journal of Thermal Analysis and Calorimetry, 2004, 77, 2, 541-554, https://doi.org/10.1023/B:JTAN.0000038993.61782.ba
. [all data]
Romero, 1999
Romero, S.,
Solubility behavior of polymorphs I and II of mefenamic acid in solvent mixtures,
International Journal of Pharmaceutics, 1999, 178, 2, 193-202, https://doi.org/10.1016/S0378-5173(98)00375-5
. [all data]
Notes
Go To: Top, Phase change data, References
- Symbols used in this document:
ΔfusH Enthalpy of fusion ΔsubH Enthalpy of sublimation ΔsubH° Enthalpy of sublimation at standard conditions - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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