Ephedrine
- Formula: C10H15NO
- Molecular weight: 165.2322
- IUPAC Standard InChI: InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10-/m1/s1
- IUPAC Standard InChIKey: KWGRBVOPPLSCSI-PSASIEDQSA-N
- CAS Registry Number: 299-42-3
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Stereoisomers:
- Other names: (-)-Ephedrine; L-Ephedrine; Efedrin; Ephedrin; Benzenemethanol, α-[1-(methylamino)ethyl]-, [R-(R*,S*)]-; α-Hydroxy-β-methylamino propylbenzene; (-)-α-(1-Methylaminoethyl)benzyl alcohol; i-Sedrin; l-α-(1-Methylaminoethyl)benzyl alcohol; l-2-Methylamino-1-phenylpropanol; Ephedrine, l-(-)-; Ephedrital; Ephedrol; Ephedrosan; Ephedrotal; Ephedsol; Ephendronal; Ephoxamin; Fedrin; Kratedyn; Lexofedrin; Manadrin; Mandrin; Nasol; Norephedrine, N-methyl-; Sanedrine; Vencipon; Zephrol; 1-Hydroxy-2-methylamino-1-phenylpropane, (1R,2S)-; 1-Phenyl-2-methylaminopropanol, (1R,2S)-; Biophedrin; Eciphin; Ephedral; Ephedremal; 1(R),2(S)-erythro-(-)-Ephedrine; (-)-(1R,2S)-Ephedrine; (-)-erythro-Ephedrine; Ephedrine l form; l-α-[1-(Methylamino)ethyl]benzenemethanol; l-Erythro-2-(methylamino)-1-phenylpropan-1-ol; 2-(Methylamino)-1-phenyl-1-propanol, (1R,2S)-; Benzenemethanol, α-((1S)-1-(methylamino)ethyl)-, (αR)-; NSC 170951; NSC 8971
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Normal alkane RI, non-polar column, temperature ramp
Go To: Top, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
| Column type | Packed | Capillary | Capillary | Capillary | Packed |
|---|---|---|---|---|---|
| Active phase | SE-30 | DB-1 | DB-5 | BP-1 | OV-1 |
| Column length (m) | 2. | 30. | 15. | 12. | 2. |
| Carrier gas | Nitrogen | He | He | He | |
| Substrate | Chromosorb G AW DMCS (80-100 mesh) | Gas Chrom P | |||
| Column diameter (mm) | 0.25 | 0.25 | 0.22 | ||
| Phase thickness (μm) | 0.25 | 0.2 | 0.25 | ||
| Tstart (C) | 100. | 40. | 100. | 120. | 120. |
| Tend (C) | 300. | 250. | 150. | 280. | 200. |
| Heat rate (K/min) | 25. | 10. | 8. | 2.5 | |
| Initial hold (min) | 2. | ||||
| Final hold (min) | 5. | ||||
| I | 1363. | 1363. | 1339. | 1350. | 1350. |
| Reference | MHA, 9999 | Yashiki, Kojima, et al., 1995 | Phillips, Logan, et al., 1990 | Stowell and Wilson, 1985 | Marozzi, Gambaro, et al., 1982 |
| Comment | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI |
| Column type | Packed | Packed | Packed |
|---|---|---|---|
| Active phase | SE-30 | SE-30 | SE-30 |
| Column length (m) | 2. | 2. | 2. |
| Carrier gas | Nitrogen | N2 | |
| Substrate | Gas Chrom P | Chromosorb W AW DMS (80-100 mesh) | Chromosorb W AW DMS |
| Column diameter (mm) | |||
| Phase thickness (μm) | |||
| Tstart (C) | 120. | 130. | 130. |
| Tend (C) | 200. | 290. | 290. |
| Heat rate (K/min) | 2.5 | 8. | 8. |
| Initial hold (min) | 2. | 2. | |
| Final hold (min) | 8. | 8. | |
| I | 1370. | 1370. | 1370. |
| Reference | Marozzi, Gambaro, et al., 1982 | Peel and Perrigo, 1976 | Peel and Perrigo, 1975 |
| Comment | MSDC-RI | MSDC-RI | MSDC-RI |
References
Go To: Top, Normal alkane RI, non-polar column, temperature ramp, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
MHA, 9999
MHA, Directorate of ForensicScience.,
Forensic Toxicology, 9999. [all data]
Yashiki, Kojima, et al., 1995
Yashiki, M.; Kojima, T.; Miyazaki, T.; Nagasawa, N.; Iwasaki, Y.; Hara, K.,
Detection of amphetamines in urine using head space-solid phase microextraction and chemical ionization selected ion monitoring,
Forensic Sci. Int., 1995, 76, 3, 169-177, https://doi.org/10.1016/0379-0738(95)01819-0
. [all data]
Phillips, Logan, et al., 1990
Phillips, A.M.; Logan, B.K.; Stafford, D.T.,
Further applications for capillary gas chromatography in routine quantitative toxicological analyses,
J. Hi. Res. Chromatogr., 1990, 13, 11, 754-758, https://doi.org/10.1002/jhrc.1240131106
. [all data]
Stowell and Wilson, 1985
Stowell, A.; Wilson, L.,
Use of retention indices in drug screening by capillary gas chromatography, Rep. # CD 2362, Department of Scientific and Industrial Reseach, Chemistry Division, Lower Hutt, NZ, 1985, 32. [all data]
Marozzi, Gambaro, et al., 1982
Marozzi, E.; Gambaro, V.; Saligari, E.; Mariani, R.; Lodi, F.,
Use of the retention index in gas chromatographic studies of drugs,
J. Anal. Toxicol., 1982, 6, 4, 185-192, https://doi.org/10.1093/jat/6.4.185
. [all data]
Peel and Perrigo, 1976
Peel, H.W.; Perrigo, B.,
A practical gas chromatographic screening procedure for toxicological analysis,
Can. Soc. Forens. Sci. J., 1976, 9, 2, 69-74, https://doi.org/10.1080/00085030.1976.10757247
. [all data]
Peel and Perrigo, 1975
Peel, H.W.; Perrigo, B.,
A practical gas chromatographic screening procedure for toxicological analysis,
Can.Soc.Forens.Sci.J., 1975, 9, 2, 69-74, https://doi.org/10.1080/00085030.1976.10757247
. [all data]
Notes
Go To: Top, Normal alkane RI, non-polar column, temperature ramp, References
- Symbols used in this document:
Tend Final temperature Tstart Initial temperature - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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