Atenolol


Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Quantity Value Units Method Reference Comment
Δsub140.0 ± 3.7kJ/molGSPerlovich, Volkova, et al., 2007Based on data from 396. - 418. K.

Enthalpy of fusion

ΔfusH (kJ/mol) Temperature (K) Method Reference
38.7426.1DSCPerlovich, Volkova, et al., 2007
35.66423.4DSCLi, Zell, et al., 1999

References

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Perlovich, Volkova, et al., 2007
Perlovich, German L.; Volkova, Tatyana V.; Bauer-Brandl, Annette, Thermodynamic Study of Sublimation, Solubility, Solvation, and Distribution Processes of Atenolol and Pindolol, Mol. Pharmaceutics, 2007, 4, 6, 929-935, https://doi.org/10.1021/mp070039b . [all data]

Li, Zell, et al., 1999
Li, Z. Jane; Zell, Mark T.; Munson, Eric J.; Grant, David J.W., Characterization of racemic species of chiral drugs using thermal analysis, thermodynamic calculation, and structural studies, J. Pharm. Sci., 1999, 88, 3, 337-346, https://doi.org/10.1021/js980205u . [all data]


Notes

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