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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Enthalpy of sublimation

DeltasubH (kJ/mol) Temperature (K) Method Reference
128.3 ± 0.5341. - 397.GSPerlovich, Kurkov, et al., 2004

Enthalpy of fusion

DeltafusH (kJ/mol) Temperature (K) Method Reference
34.2428.8DSCWassvik, Holmén, et al., 2006
31.5428.5N/ANeau, Bhandarkar, et al., 1997
29.41439.2N/AClaramonte, Vialard, et al., 1993


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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Perlovich, Kurkov, et al., 2004
Perlovich, German L.; Kurkov, Sergey V.; Kinchin, Andrey N.; Bauer-Brandl, Annette, Thermodynamics of solutions III: comparison of the solvation of (+)-naproxen with other NSAIDs, European Journal of Pharmaceutics and Biopharmaceutics, 2004, 57, 2, 411-420, https://doi.org/10.1016/j.ejpb.2003.10.021 . [all data]

Wassvik, Holmén, et al., 2006
Wassvik, Carola M.; Holmén, Anders G.; Bergström, Christel A.S.; Zamora, Ismael; Artursson, Per, Contribution of solid-state properties to the aqueous solubility of drugs, European Journal of Pharmaceutical Sciences, 2006, 29, 3-4, 294-305, https://doi.org/10.1016/j.ejps.2006.05.013 . [all data]

Neau, Bhandarkar, et al., 1997
Neau, Steven H.; Bhandarkar, Satej V.; Hellmuth, Eckhard W., Pharmaceutical Research, 1997, 14, 5, 601-605, https://doi.org/10.1023/A:1012148910975 . [all data]

Claramonte, Vialard, et al., 1993
Claramonte, M.D. Contreras; Vialard, A. Parera; Vilchez, F. Girela, An application of regular solution theory in the study of the solubility of naproxen in some solvents used in topical preparations, International Journal of Pharmaceutics, 1993, 94, 1-3, 23-30, https://doi.org/10.1016/0378-5173(93)90005-Z . [all data]


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