Clonazepam
- Formula: C15H10ClN3O3
- Molecular weight: 315.711
- IUPAC Standard InChI: InChI=1S/C15H10ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11)18-14(20)8-17-15/h1-7H,8H2,(H,18,20)
- IUPAC Standard InChIKey: DGBIGWXXNGSACT-UHFFFAOYSA-N
- CAS Registry Number: 1622-61-3
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
View 3d structure (requires JavaScript / HTML 5) - Other names: 2H-1,4-Benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-7-nitro-; 2H-1,4-Benzodiazepin-2-one, 5-(o-chlorophenyl)-1,3-dihydro-7-nitro-; Chlonazepam; Rivotril; Ro 5-4023; Cloazepam; Clonopin; Iktorivil; Ro 4-8180; 1,3-Dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one; 5-(o-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one; 5-(2-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one; Klonopin; Landsen; 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one; Antelepsin; Clonex; Kenoket; Lonazep; NSC 179913; Paxam; 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 106955-87-7
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Van Den Dool and Kratz RI, non-polar column, temperature ramp
Go To: Top, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
| Column type | Capillary | Capillary | Packed |
|---|---|---|---|
| Active phase | VF-5MS | SPB-1 | SE-30 |
| Column length (m) | 30. | 30. | 1.8 |
| Carrier gas | He | He | N2 |
| Substrate | Chromosorb W | ||
| Column diameter (mm) | 0.25 | 0.75 | |
| Phase thickness (μm) | 0.25 | 1.0 | |
| Tstart (C) | 60. | 160. | 130. |
| Tend (C) | 270. | 280. | 290. |
| Heat rate (K/min) | 10. | 8. | |
| Initial hold (min) | 2. | ||
| Final hold (min) | 12. | 8. | |
| I | 2934.6 | 2803. | 2860. |
| Reference | Tretyakov, 2014 | Christ, Noomano, et al., 1988 | Perrigo and Peel, 1981 |
| Comment | MSDC-RI | MSDC-RI | MSDC-RI |
References
Go To: Top, Van Den Dool and Kratz RI, non-polar column, temperature ramp, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Tretyakov, 2014
Tretyakov, K.V.,
Retention Data. NIST Mass Spectrometry Data Center., NIST Mass Spectrometry Data Center, 2014. [all data]
Christ, Noomano, et al., 1988
Christ, D.W.; Noomano, P.; Rosas, M.; Rhone, D.,
Retention indices by wide-bore capillary gas chromatography with nitrogen-phosphorus detection,
J. Anal. Toxicol., 1988, 12, 2, 84-88, https://doi.org/10.1093/jat/12.2.84
. [all data]
Perrigo and Peel, 1981
Perrigo, B.J.; Peel, H.W.,
The use of retention indices and temperature-programmed gas chromatography in analytical toxicology,
J. Chromatogr. Sci., 1981, 19, 5, 219-226, https://doi.org/10.1093/chromsci/19.5.219
. [all data]
Notes
Go To: Top, Van Den Dool and Kratz RI, non-polar column, temperature ramp, References
- Symbols used in this document:
Tend Final temperature Tstart Initial temperature - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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