Halothane
- Formula: C2HBrClF3
- Molecular weight: 197.382
- IUPAC Standard InChIKey: BCQZXOMGPXTTIC-UHFFFAOYSA-N
- CAS Registry Number: 151-67-7
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Other names: Ethane, 2-bromo-2-chloro-1,1,1-trifluoro-; Anestan; Fluktan; Fluorotane; Fluorothane; Fluothane; Ftorotan; Ftuorotan; Halan; Halotan; Halotano; Halothan; Halsan; Narcotan; Narcotane; Narkotan; CF3CHClBr; 1,1,1-Trifluoro-2-bromo-2-chloroethane; 2-Bromo-2-chloro-1,1,1-trifluoroethane; 1,1,1-Trifluoro-2-chloro-2-bromoethane; FREON 123B1; 1-Bromo-1-chloro-2,2,2-trifluoroethane; Bromochlorotrifluoroethane; 2,2,2-Trifluoro-1-chloro-1-bromoethane; Chalothane; Ethane, 1-bromo-1-chloro-2,2,2-trifluoro-; Narcotann ne-spofa; Rhodialothan; (.+/-.))-Halothane; Alotano; NSC 143490
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Phase change data
Go To: Top, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled as indicated in comments:
BS - Robert L. Brown and Stephen E. Stein
TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director
AC - William E. Acree, Jr., James S. Chickos
ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein
DH - Eugene S. Domalski and Elizabeth D. Hearing
Quantity | Value | Units | Method | Reference | Comment |
---|---|---|---|---|---|
Tboil | 323.4 | K | N/A | Aldrich Chemical Company Inc., 1990 | BS |
Tboil | 596.4 | K | N/A | Francesconi, Comelli, et al., 1990 | Uncertainty assigned by TRC = 0.4 K; TRC |
Tboil | 323. | K | N/A | PCR Inc., 1990 | BS |
Tboil | 323.3 | K | N/A | Majer and Svoboda, 1985 | |
Tboil | 323.42 | K | N/A | Pashchenko and Varushchenko, 1985 | Uncertainty assigned by TRC = 0.01 K; TRC |
Quantity | Value | Units | Method | Reference | Comment |
Tfus | 157.4 | K | N/A | Golovanova and Kolesov, 1984 | Uncertainty assigned by TRC = 0.2 K; TRC |
Quantity | Value | Units | Method | Reference | Comment |
Tc | 496.3 | K | N/A | Majer and Svoboda, 1985 | |
Quantity | Value | Units | Method | Reference | Comment |
ΔvapH° | 7.12 | kcal/mol | N/A | Majer and Svoboda, 1985 | |
ΔvapH° | 7.12 ± 0.1 | kcal/mol | N/A | Varushchenko, Druzhinina, et al., 2007 | Based on data from 302. to 323. K. See also Pashchenko and Varushchenko, 1985.; AC |
ΔvapH° | 7.065 ± 0.079 | kcal/mol | V | Papina, Erastov, et al., 1981 | ALS |
ΔvapH° | 7.07 ± 0.07 | kcal/mol | N/A | Papina, Erastov, et al., 1981 | AC |
ΔvapH° | 7.07 ± 0.02 | kcal/mol | C | Majer, Svoboda, et al., 1980 | AC |
Enthalpy of vaporization
ΔvapH (kcal/mol) | Temperature (K) | Method | Reference | Comment |
---|---|---|---|---|
6.711 | 323.3 | N/A | Majer and Svoboda, 1985 | |
7.17 | 310. | A | Stephenson and Malanowski, 1987 | Based on data from 298. to 323. K.; AC |
7.93 | 237. | A | Stephenson and Malanowski, 1987 | Based on data from 222. to 329. K. See also Bottomley and Seiflow, 2007 and Dykyj, 1970.; AC |
6.86 ± 0.02 | 313. | C | Majer, Svoboda, et al., 1980 | AC |
6.64 ± 0.02 | 328. | C | Majer, Svoboda, et al., 1980 | AC |
6.41 ± 0.02 | 343. | C | Majer, Svoboda, et al., 1980 | AC |
8.20 | 242. | N/A | Kudryashov and Savechenko, 1965 | Based on data from 227. to 318. K.; AC |
Enthalpy of vaporization
ΔvapH =
A exp(-βTr) (1 − Tr)β
ΔvapH =
Enthalpy of vaporization (at saturation pressure)
(kcal/mol)
Tr = reduced temperature (T / Tc)
View plot Requires a JavaScript / HTML 5 canvas capable browser.
Temperature (K) | A (kcal/mol) | β | Tc (K) | Reference | Comment |
---|---|---|---|---|---|
298. to 328. | 10.93 | 0.286 | 496.3 | Majer and Svoboda, 1985 |
Antoine Equation Parameters
log10(P) = A − (B / (T + C))
P = vapor pressure (atm)
T = temperature (K)
View plot Requires a JavaScript / HTML 5 canvas capable browser.
Temperature (K) | A | B | C | Reference | Comment |
---|---|---|---|---|---|
222.5 to 328.50 | 3.81954 | 1016.075 | -57.581 | Bottomley and Seiflow, 1963 | Coefficents calculated by NIST from author's data. |
Enthalpy of fusion
ΔfusH (kcal/mol) | Temperature (K) | Reference | Comment |
---|---|---|---|
1.157 | 157.4 | Golovanova and Kolesov, 1984, 2 | DH |
1.16 | 154.7 | Domalski and Hearing, 1996 | AC |
Entropy of fusion
ΔfusS (cal/mol*K) | Temperature (K) | Reference | Comment |
---|---|---|---|
7.34 | 157.4 | Golovanova and Kolesov, 1984, 2 | DH |
References
Go To: Top, Phase change data, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Aldrich Chemical Company Inc., 1990
Aldrich Chemical Company Inc.,
Catalog Handbook of Fine Chemicals, Aldrich Chemical Company, Inc., Milwaukee WI, 1990, 1. [all data]
Francesconi, Comelli, et al., 1990
Francesconi, R.; Comelli, F.; Giacomo, D.,
Excess Enthalpy for the Binary System 1,3-Dioxolane + Halothane,
J. Chem. Eng. Data, 1990, 35, 190. [all data]
PCR Inc., 1990
PCR Inc.,
Research Chemicals Catalog 1990-1991, PCR Inc., Gainesville, FL, 1990, 1. [all data]
Majer and Svoboda, 1985
Majer, V.; Svoboda, V.,
Enthalpies of Vaporization of Organic Compounds: A Critical Review and Data Compilation, Blackwell Scientific Publications, Oxford, 1985, 300. [all data]
Pashchenko and Varushchenko, 1985
Pashchenko, L.L.; Varushchenko, R.M.,
Zh. Obshch. Khim., 1985, 55, 721. [all data]
Golovanova and Kolesov, 1984
Golovanova, Y.G.; Kolesov, V.P.,
Enthalpies of melting, melting temperatures, and cryoscopic constants of some haloorganic compounds,
Vestn. Mosk. Univ., Ser. 2: Khim., 1984, 25, 244. [all data]
Varushchenko, Druzhinina, et al., 2007
Varushchenko, R.M.; Druzhinina, A.I.; Kuramshina, G.M.; Dorofeeva, O.V.,
Thermodynamics of vaporization of some freons and halogenated ethanes and propanes,
Fluid Phase Equilibria, 2007, 256, 1-2, 112-122, https://doi.org/10.1016/j.fluid.2007.02.017
. [all data]
Papina, Erastov, et al., 1981
Papina, T.S.; Erastov, P.A.; Kolesov, V.P.,
The enthalpies of formation of 1,1,1-trifluoro-2-chloro-2-bromoethane and 1,1,2-trifluoro-2-chloro-1-bromoethane,
J. Chem. Thermodyn., 1981, 13, 683-689. [all data]
Majer, Svoboda, et al., 1980
Majer, Vladimír; Svoboda, Václav; Posta, Antonín; Pick, Jirí,
Determination of heats of vaporization and some other thermodynamic quantities for several fluorinated halogen derivatives of ethane and propane,
Collect. Czech. Chem. Commun., 1980, 45, 11, 3063-3068, https://doi.org/10.1135/cccc19803063
. [all data]
Stephenson and Malanowski, 1987
Stephenson, Richard M.; Malanowski, Stanislaw,
Handbook of the Thermodynamics of Organic Compounds, 1987, https://doi.org/10.1007/978-94-009-3173-2
. [all data]
Bottomley and Seiflow, 2007
Bottomley, G.A.; Seiflow, G.H.P.,
Vapour pressure and vapour density of halothane (2-bromo-2-chloro-1,1,1-trifluoroethane),
J. Appl. Chem., 2007, 13, 9, 399-402, https://doi.org/10.1002/jctb.5010130905
. [all data]
Dykyj, 1970
Dykyj, J.,
Petrochemica, 1970, 10, 2, 51. [all data]
Kudryashov and Savechenko, 1965
Kudryashov, I.V.; Savechenko, R.I.,
Izv. Vyssh. Uchebn. Zaved., Khim. Khim. Tekhnol., 1965, 8, 602. [all data]
Bottomley and Seiflow, 1963
Bottomley, G.A.; Seiflow, G.H.F.,
Vapour Pressure and Vapour Density of Halothane (2-Bromo-2-Chloro-1,1,1-Trifluoroethane),
J. Appl. Chem., 1963, 13, 9, 399-402, https://doi.org/10.1002/jctb.5010130905
. [all data]
Golovanova and Kolesov, 1984, 2
Golovanova, Yu.G.; Kolesov, V.P.,
Enthalpies of melting, melting temperatures, and cryoscopic constants of some haloorganic compounds, Vestn. Mosk Univ.,
Ser. 2: Khim., 1984, 25(3), 244-248. [all data]
Domalski and Hearing, 1996
Domalski, Eugene S.; Hearing, Elizabeth D.,
Heat Capacities and Entropies of Organic Compounds in the Condensed Phase. Volume III,
J. Phys. Chem. Ref. Data, 1996, 25, 1, 1, https://doi.org/10.1063/1.555985
. [all data]
Notes
Go To: Top, Phase change data, References
- Symbols used in this document:
Tboil Boiling point Tc Critical temperature Tfus Fusion (melting) point ΔfusH Enthalpy of fusion ΔfusS Entropy of fusion ΔvapH Enthalpy of vaporization ΔvapH° Enthalpy of vaporization at standard conditions - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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