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Tolfenamic acid


Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Quantity Value Units Method Reference Comment
Deltasub128.4 ± 0.8kJ/molGSSurov, Terekhova, et al., 2009Based on data from 346. - 373. K.

Enthalpy of sublimation

DeltasubH (kJ/mol) Temperature (K) Method Reference Comment
125.7 ± 0.8360.GSSurov, Terekhova, et al., 2009Based on data from 346. - 373. K.

Enthalpy of fusion

DeltafusH (kJ/mol) Temperature (K) Method Reference Comment
49.0485.8DSCSurov, Szterner, et al., 2009Based on data from yellow crys K.
38.6484.3DSCSurov, Terekhova, et al., 2009 
41.2485.3N/ABergström, Wassvik, et al., 2007 

References

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Surov, Terekhova, et al., 2009
Surov, Artem O.; Terekhova, Irina V.; Bauer-Brandl, Annette; Perlovich, German L., Thermodynamic and Structural Aspects of Some Fenamate Molecular Crystals, Crystal Growth & Design, 2009, 9, 7, 3265-3272, https://doi.org/10.1021/cg900002q . [all data]

Surov, Szterner, et al., 2009
Surov, Artem O.; Szterner, Piotr; Zielenkiewicz, Wojciech; Perlovich, German L., Thermodynamic and structural study of tolfenamic acid polymorphs, Journal of Pharmaceutical and Biomedical Analysis, 2009, 50, 5, 831-840, https://doi.org/10.1016/j.jpba.2009.06.045 . [all data]

Bergström, Wassvik, et al., 2007
Bergström, Christel A.S.; Wassvik, Carola M.; Johansson, Kajsa; Hubatsch, Ina, Poorly Soluble Marketed Drugs Display Solvation Limited Solubility, J. Med. Chem., 2007, 50, 23, 5858-5862, https://doi.org/10.1021/jm0706416 . [all data]


Notes

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