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Ketoprofen


Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Enthalpy of sublimation

DeltasubH (kJ/mol) Temperature (K) Method Reference
110.1 ± 0.5341. - 365.GSPerlovich, Kurkov, et al., 2003

Enthalpy of fusion

DeltafusH (kJ/mol) Temperature (K) Method Reference Comment
37.3368.DSCWassvik, Holmén, et al., 2006See also Wassvik, Holmén, et al., 2008.
25.04369.N/AMura, 1998See also Mura, Faucci, et al., 1999.
28.23367.4N/AEspitalier, Biscans, et al., 1995 

References

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Perlovich, Kurkov, et al., 2003
Perlovich, German L.; Kurkov, Sergey V.; Kinchin, Andrey N.; Bauer-Brandl, Annette, Thermodynamics of solutions IV: Solvation of ketoprofen in comparison with other NSAIDs, J. Pharm. Sci., 2003, 92, 12, 2502-2511, https://doi.org/10.1002/jps.10512 . [all data]

Wassvik, Holmén, et al., 2006
Wassvik, Carola M.; Holmén, Anders G.; Bergström, Christel A.S.; Zamora, Ismael; Artursson, Per, Contribution of solid-state properties to the aqueous solubility of drugs, European Journal of Pharmaceutical Sciences, 2006, 29, 3-4, 294-305, https://doi.org/10.1016/j.ejps.2006.05.013 . [all data]

Wassvik, Holmén, et al., 2008
Wassvik, Carola M.; Holmén, Anders G.; Draheim, Rieke; Artursson, Per; Bergström, Christel A.S., Molecular Characteristics for Solid-State Limited Solubility, J. Med. Chem., 2008, 51, 10, 3035-3039, https://doi.org/10.1021/jm701587d . [all data]

Mura, 1998
Mura, P., Interactions of ketoprofen and ibuprofen with «beta»-cyclodextrins in solution and in the solid state, International Journal of Pharmaceutics, 1998, 166, 2, 189-203, https://doi.org/10.1016/S0378-5173(98)00035-0 . [all data]

Mura, Faucci, et al., 1999
Mura, P.; Faucci, M.T.; Parrini, P.L.; Furlanetto, S.; Pinzauti, S., Influence of the preparation method on the physicochemical properties of ketoprofen--cyclodextrin binary systems, International Journal of Pharmaceutics, 1999, 179, 1, 117-128, https://doi.org/10.1016/S0378-5173(98)00390-1 . [all data]

Espitalier, Biscans, et al., 1995
Espitalier, F.; Biscans, B.; Peyrigain, P. Sere; Laguérie, C., Ternary diagram: alpha-(3-benzoylphenyl)-propionic acid (ketoprofen) in acetone«58872»water mixtures at different temperatures. Experimental data and predicted results, Fluid Phase Equilibria, 1995, 113, 1-2, 151-171, https://doi.org/10.1016/0378-3812(95)02806-8 . [all data]


Notes

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