Nalidixic Acid
- Formula: C12H12N2O3
- Molecular weight: 232.2353
- IUPAC Standard InChI: InChI=1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17)
- IUPAC Standard InChIKey: MHWLWQUZZRMNGJ-UHFFFAOYSA-N
- CAS Registry Number: 389-08-2
- Chemical structure:
This structure is also available as a 2d Mol file - Other names: 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-; Cybis; Dixiben; Dixinal; Eucistin; Innoxalon; Jicsron; Nalidic acid; Nalidixan; Nalidixate; Nalidixin; Nalidixinic acid; Nalitucsan; Nalix; Nalurin; Naxuril; Negram; NegGram; Nevigramon; Nogram; NCI-C56199; Sicmylon; Unaserus; Urisal; Uronidix; Wintomylon; WIN 18,320; WIN 18320; 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxilic acid; 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid; 1-Ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid; 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; 1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid; 3-Carboxy-1-ethyl-7-methyl-1,8-naphthidin-4-one; Acide 1-etil-7-metil-1,8-naftiridin-4-one-3-carbossilico; Acide nalidixico; Acide nalidixique; 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure; Betaxina; Eucisten; Kusnarin; Nalidicron; Narigix; Nicelate; NSC-82174; Poleon; Specifen; Uralgin; Uriben; Uriclar; Urodixin; Uroman; Uroneg; Uropan; Nalidixane; Innoxalomn; Specifin; 3-Carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one; Nacid; 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (nalidixic acid)
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Phase change data
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: William E. Acree, Jr., James S. Chickos
Enthalpy of fusion
| ΔfusH (kJ/mol) | Temperature (K) | Method | Reference |
|---|---|---|---|
| 35.92 | 501.9 | DSC | Romero, Bustamante, et al., 2004 |
| 35.92 | 501.9 | N/A | Bustamante, Romero, et al., 1998 |
References
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Romero, Bustamante, et al., 2004
Romero, Susana; Bustamante, Pilar; Escalera, Begoña; Mura, Paola; Cirri, Marzia,
Influence of solvent composition on the solid phase at equilibrium with saturated solutions of quinolones in different solvent mixtures,
Journal of Pharmaceutical and Biomedical Analysis, 2004, 35, 4, 715-726, https://doi.org/10.1016/j.jpba.2004.02.006
. [all data]
Bustamante, Romero, et al., 1998
Bustamante, P.; Romero, S.; Pe«65533»a, A.; Escalera, B.; Reillo, A.,
Enthalpy-entropy compensation for the solubility of drugs in solvent mixtures: Paracetamol, acetanilide, and nalidixic acid in dioxane-water,
J. Pharm. Sci., 1998, 87, 12, 1590-1596, https://doi.org/10.1021/js980149x
. [all data]
Notes
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- Symbols used in this document:
ΔfusH Enthalpy of fusion - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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