Temazepam

• Formula: C₁₆H₁₃ClN₂O₂
• Molecular weight: 300.740
• IUPAC Standard InChI: InChI=1S/C16H13ClN2O2/c1-19-13-8-7-11(17)9-12(13)14(18-15(20)16(19)21)10-5-3-2-4-6-10/h2-9,15,20H,1H3 Copy

  
• IUPAC Standard InChIKey: SEQDDYPDSLOBDC-UHFFFAOYSA-N Copy
• CAS Registry Number: 846-50-4
• Chemical structure:
  This structure is also available as a 2d Mol file or as a computed 3d SD file
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• Other names: 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-; Crisonar; ER 115; K-3917; Levanxene; Levanxol; Methyloxazepam; N-Methyloxazepam; Oxydiazepam; Ro 5-5345; Wy-3917; 3-Hydroxydiazepam; Euhypnos; Hydroxydiazepam; Mabertin; Restoril; Signopam; 7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one; 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-3-hydroxy-1-methyl-5-phenyl-; Cerepax; 1,3-Dihydro-7-chloro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one; Normison; Planum; Remestan; Euipnos; Gelthix; Levanzene; Perdorm; Ro-5-5354; Diazepam, 3-hydroxy; NSC 246303; Tenox; 7-Chloro-3-hydroxy-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Temazepam II; 7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one (temazepam)
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• Information on this page:
  • Phase change data
  • References
  • Notes
• Other data available:
  • Mass spectrum (electron ionization)
  • Gas Chromatography
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Phase change data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: William E. Acree, Jr., James S. Chickos

Enthalpy of fusion

References

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Van den Mooter, Augustijns, et al., 1998
Van den Mooter, G.; Augustijns, P.; Kinget, R., Application of the thermodynamics of mobile order and disorder to explain the solubility of temazepam in aqueous solutions of polyethylene glycol 6000, International Journal of Pharmaceutics, 1998, 164, 1-2, 81-89, https://doi.org/10.1016/S0378-5173(97)00400-6 . [all data]

Richardson, McCafferty, et al., 1992
Richardson, P.J.; McCafferty, D.F.; Woolfson, A.D., Determination of three-component partial solubility parameters for temazepam and the effects of change in partial molal volume on the thermodynamics of drugs solubility, International Journal of Pharmaceutics, 1992, 78, 1-3, 189-198, https://doi.org/10.1016/0378-5173(92)90370-H . [all data]

Notes

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• Symbols used in this document:
  

  ΔfusH

  Enthalpy of fusion

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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