5-Cholesten-3-β,27-diol, TMS
- Formula: C33H62O2Si2
- Molecular weight: 547.0152
- IUPAC Standard InChI: InChI=1S/C33H62O2Si2/c1-24(23-34-36(5,6)7)12-11-13-25(2)29-16-17-30-28-15-14-26-22-27(35-37(8,9)10)18-20-32(26,3)31(28)19-21-33(29,30)4/h14,24-25,27-31H,11-13,15-23H2,1-10H3/t24?,25-,27?,28?,29?,30?,31?,32?,33?/m1/s1
- IUPAC Standard InChIKey: XPOWNWJGSYYWLA-TZWGRJOJSA-N
- Chemical structure:
This structure is also available as a 2d Mol file - Stereoisomers:
- Other names: 27-Hydroxycholesterol, TMS; 5-Cholesten-3B(25R),26-diol, TMS; 5-Cholesten-3-β,26-diol, TMS; 26-Hydroxycholesterol, di-TMS
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- Other data available:
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Normal alkane RI, non-polar column, custom temperature program
Go To: Top, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
| Column type | Capillary | Capillary |
|---|---|---|
| Active phase | Ultra-1 | Ultra-1 |
| Column length (m) | 25. | 25. |
| Carrier gas | H2 | |
| Substrate | ||
| Column diameter (mm) | 0.32 | 0.32 |
| Phase thickness (μm) | 0.17 | 0.17 |
| Program | 50 0C (3 min) -> 185 0C 5 K/min -> 280 0C | 50C (3min) => (rapidly) => 185C => 5C/min => 280C |
| I | 3450. | 3455. |
| Reference | Axelson, Ellis, et al., 2000 | Axelson and Larsson, 1996 |
| Comment | MSDC-RI | MSDC-RI |
References
Go To: Top, Normal alkane RI, non-polar column, custom temperature program, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Axelson, Ellis, et al., 2000
Axelson, M.; Ellis, E.; Mörk, B.; Garmark, K.; Abrahamsson, A.; Björkhem, I.; Ericzon, B.-G.; Einarsson, C.,
Bile acid synthesis in cultured human hepatocytes: support for an alternative biosynthetic pathway to cholic acid,
Hepatology, 2000, 31, 6, 1305-1312, https://doi.org/10.1053/jhep.2000.7877
. [all data]
Axelson and Larsson, 1996
Axelson, M.; Larsson, O.,
27-Hydroxylated low density lipoprotein (LDL) cholesterol can be converted to 7α,27-Dihydroxy-4-cholesten-3-one (cytosterone) before suppressing cholesterol production in normal human fibroblasts. Evidence that an altered metabolism of LDL cholesterol can underlie a defective feedback control in malignant cells,
J. Biol. Chem., 1996, 271, 22, 12724-12736. [all data]
Notes
Go To: Top, Normal alkane RI, non-polar column, custom temperature program, References
- Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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