Methadone
- Formula: C21H27NO
- Molecular weight: 309.4452
- IUPAC Standard InChI: InChI=1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3
- IUPAC Standard InChIKey: USSIQXCVUWKGNF-UHFFFAOYSA-N
- CAS Registry Number: 76-99-3
- Chemical structure:
This structure is also available as a 2d Mol file - Species with the same structure:
- Other names: 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-; Adanon; Algovetin; Amidon; Amidone; Diaminon; Dolophin; Heptadone; Ketalgin; Phenadone; Physeptone; Dolophine; Heptanon; Methadon; 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, (.+/-.)-; (.+/-.)-Methadone; dl-Methadone; Racemic methadone; 2-Dimethylamino-4,4-diphenyl-5-heptanone; 6-(Dimethylamino)-4,4-diphenyl-3-heptanone; Heptanon (pharmaceutical); Sedo-Rapide; Mecodin; Polamidon; Polamidone; Adanon hydrochloride; 297-88-1; Methadone M
- Information on this page:
- Other data available:
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Normal alkane RI, non-polar column, temperature ramp
Go To: Top, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
| Column type | Capillary | Capillary | Capillary | Capillary | Packed |
|---|---|---|---|---|---|
| Active phase | DB-5 | BP-1 | BP-1 | BP-1 | SE-30 |
| Column length (m) | 15. | 12. | 12. | 12. | 2. |
| Carrier gas | He | He | He | He | Nitrogen |
| Substrate | Chromosorb W AW DMS (80-100 mesh) | ||||
| Column diameter (mm) | 0.25 | 0.22 | 0.22 | 0.22 | |
| Phase thickness (μm) | 0.2 | 0.25 | 0.25 | 0.25 | |
| Tstart (C) | 185. | 100. | 120. | 50. | 130. |
| Tend (C) | 270. | 295. | 280. | 300. | 290. |
| Heat rate (K/min) | 10. | 5. | 8. | 20. | 8. |
| Initial hold (min) | 2. | ||||
| Final hold (min) | 8. | ||||
| I | 2121. | 2121. | 2131. | 2135. | 2140. |
| Reference | Phillips, Logan, et al., 1990 | Stowell and Wilson, 1985 | Stowell and Wilson, 1985 | Stowell and Wilson, 1985 | Peel and Perrigo, 1976 |
| Comment | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI |
| Column type | Packed |
|---|---|
| Active phase | SE-30 |
| Column length (m) | 2. |
| Carrier gas | N2 |
| Substrate | Chromosorb W AW DMS |
| Column diameter (mm) | |
| Phase thickness (μm) | |
| Tstart (C) | 130. |
| Tend (C) | 290. |
| Heat rate (K/min) | 8. |
| Initial hold (min) | 2. |
| Final hold (min) | 8. |
| I | 2140. |
| Reference | Peel and Perrigo, 1975 |
| Comment | MSDC-RI |
References
Go To: Top, Normal alkane RI, non-polar column, temperature ramp, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Phillips, Logan, et al., 1990
Phillips, A.M.; Logan, B.K.; Stafford, D.T.,
Further applications for capillary gas chromatography in routine quantitative toxicological analyses,
J. Hi. Res. Chromatogr., 1990, 13, 11, 754-758, https://doi.org/10.1002/jhrc.1240131106
. [all data]
Stowell and Wilson, 1985
Stowell, A.; Wilson, L.,
Use of retention indices in drug screening by capillary gas chromatography, Rep. # CD 2362, Department of Scientific and Industrial Reseach, Chemistry Division, Lower Hutt, NZ, 1985, 32. [all data]
Peel and Perrigo, 1976
Peel, H.W.; Perrigo, B.,
A practical gas chromatographic screening procedure for toxicological analysis,
Can. Soc. Forens. Sci. J., 1976, 9, 2, 69-74, https://doi.org/10.1080/00085030.1976.10757247
. [all data]
Peel and Perrigo, 1975
Peel, H.W.; Perrigo, B.,
A practical gas chromatographic screening procedure for toxicological analysis,
Can.Soc.Forens.Sci.J., 1975, 9, 2, 69-74, https://doi.org/10.1080/00085030.1976.10757247
. [all data]
Notes
Go To: Top, Normal alkane RI, non-polar column, temperature ramp, References
- Symbols used in this document:
Tend Final temperature Tstart Initial temperature - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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