Mefenamic Acid
- Formula: C15H15NO2
- Molecular weight: 241.2851
- IUPAC Standard InChI: InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)
- IUPAC Standard InChIKey: HYYBABOKPJLUIN-UHFFFAOYSA-N
- CAS Registry Number: 61-68-7
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Other names: Benzoic acid, 2-[(2,3-dimethylphenyl)amino]-; Anthranilic acid, N-2,3-xylyl-; AGN-1255; Bafameritin-M; Bonabol; Coslan; CL 473; CN-35355; HL 1; INF 3355; Lysalgo; Mefacit; Mephenamic acid; Mephenaminic acid; Methenamic acid; N-(2,3-Dimethylphenyl)anthranilic acid; N-(2,3-Xylyl)-2-aminobenzoic acid; N-(2,3-Xylyl)anthranilic acid; Parkemed; Ponalar; Ponstan; Ponstel; Ponstil; Ponstyl; Pontal; Tamany Bonsan; Tanston; Vialidon; 2-((2,3-Dimethylphenyl)amino)benzoic acid; 2-Diphenylaminecarboxylic acid, 2',3'-dimethyl-; Acide mefenamique; Bafhameritin-M; Mefenaminsaeure; Namphen; Ponstan forte; In-M; Mefanamic acid; Mefenacid; NSC 94437; 2-[(2,3-Dimethylphenyl)amino]benzoic acid (mefenamic acid)
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Phase change data
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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: William E. Acree, Jr., James S. Chickos
| Quantity | Value | Units | Method | Reference | Comment |
|---|---|---|---|---|---|
| ΔsubH° | 32.6 ± 0.2 | kcal/mol | GS | Surov, Terekhova, et al., 2009 | Based on data from 357. to 398. K. |
Enthalpy of sublimation
| ΔsubH (kcal/mol) | Temperature (K) | Method | Reference | Comment |
|---|---|---|---|---|
| 31.7 ± 0.2 | 377. | GS | Surov, Terekhova, et al., 2009 | Based on data from 357. to 398. K. |
Enthalpy of fusion
| ΔfusH (kcal/mol) | Temperature (K) | Method | Reference |
|---|---|---|---|
| 9.25 | 503.5 | DSC | Surov, Terekhova, et al., 2009 |
| 9.142 | 503.6 | DSC | Romero, Bustamante, et al., 2004 |
| 9.13 | 503.6 | N/A | Romero, 1999 |
Gas Chromatography
Go To: Top, Phase change data, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
Normal alkane RI, non-polar column, custom temperature program
| Column type | Active phase | I | Reference | Comment |
|---|---|---|---|---|
| Other | Methyl Silicone | 2201. | Ardrey and Moffat, 1981 | Program: not specified |
References
Go To: Top, Phase change data, Gas Chromatography, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Surov, Terekhova, et al., 2009
Surov, Artem O.; Terekhova, Irina V.; Bauer-Brandl, Annette; Perlovich, German L.,
Thermodynamic and Structural Aspects of Some Fenamate Molecular Crystals,
Crystal Growth & Design, 2009, 9, 7, 3265-3272, https://doi.org/10.1021/cg900002q
. [all data]
Romero, Bustamante, et al., 2004
Romero, S.; Bustamante, P.; Escalera, B.; Cirri, M.; Mura, P.,
Characterization of the solid phases of paracetamol and fenamates at equilibrium in saturated solutions,
Journal of Thermal Analysis and Calorimetry, 2004, 77, 2, 541-554, https://doi.org/10.1023/B:JTAN.0000038993.61782.ba
. [all data]
Romero, 1999
Romero, S.,
Solubility behavior of polymorphs I and II of mefenamic acid in solvent mixtures,
International Journal of Pharmaceutics, 1999, 178, 2, 193-202, https://doi.org/10.1016/S0378-5173(98)00375-5
. [all data]
Ardrey and Moffat, 1981
Ardrey, R.E.; Moffat, A.C.,
Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase,
J. Chromatogr., 1981, 220, 3, 195-252, https://doi.org/10.1016/S0021-9673(00)81925-1
. [all data]
Notes
Go To: Top, Phase change data, Gas Chromatography, References
- Symbols used in this document:
ΔfusH Enthalpy of fusion ΔsubH Enthalpy of sublimation ΔsubH° Enthalpy of sublimation at standard conditions - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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