Phenytoin
- Formula: C15H12N2O2
- Molecular weight: 252.2680
- IUPAC Standard InChI: InChI=1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)
- IUPAC Standard InChIKey: CXOFVDLJLONNDW-UHFFFAOYSA-N
- CAS Registry Number: 57-41-0
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Other names: 2,4-Imidazolidinedione, 5,5-diphenyl-; Hydantoin, 5,5-diphenyl-; Aleviatin; Denyl; Di-Hydan; Di-Lan; Dihycon; Dilabid; Dintoina; Diphantoin; Diphedan; Diphenine; Diphenylhydantoin; DPH; Lepitoin; Phenytoine; Sodanton; Zentropil; 5,5-Diphenyl-2,4-Imidazolidinedione; 5,5-Diphenylhydantoin; Auranile; Causoin; Comitoina; Convul; Danten; Dantinal; Dantoinal; Dantoinal klinos; Di-Phetine; Didan TDC 250; Difenilhidantoina; Difenin; Difetoin; Difhydan; Dihydantoin; Dilantin; Dilantin acid; Dilantine; Dillantin; Dintoin; Diphedal; Diphenin; Diphentyn; Diphenylan; Diphenylhydatanoin; Ditoinate; Ekko; Ekko capsules; Elepsindon; Enkelfel; Epamin; Epasmir "5"; Epdantoine simple; Epelin; Epifenyl; Epihydan; Epilan-D; Epilantin; Epinat; Epised; Eptal; Fenidantoin "s"; Fenitoina; Fentoin; Fenylepsin; Fenytoine; Gerot-epilan-D; Hidan; Hidantilo; Hidantina; Hidantina senosian; Hidantina vitoria; Hidantomin; Hindatal; Hydantal; Hydantin; Hydantoinal; Ictalis simple; Idantoil; Idantoin; Kessodanten; Labopal; Lehydan; Lepsin; Neos-Hidantoina; Neosidantoina; Novantoina; Om hidantoina simple; Om-Hydantoine; Oxylan; Phanantin; Phanatine; Phenatine; Phenatoine; Phentoin; Ritmenal; Saceril; Sanepil; Silantin; Sodantoin; Solantin; Sylantoic; Thilophenyl; Toin unicelles; TOIN; Zentronal; 5,5-Diphenylimidazolidin-2,4-dione; Citrulliamon; Dantoine; Diphentoin; Diphenylhydantoine; 5,5-Dwufenylohydantoina; Epanutin; Eptoin; Hidantal; Minetoin; NCI-C55765; Phenitoin; Solantoin; Solantyl; Diphenat; 5,5-Diphenyl-1H-imidazolidine-2,4-dione; Epasmir ''5''; Fenidantoin ''s''; Mebroin (Salt/Mix); Antisacer (Salt/Mix); Aladdin (Salt/Mix); Alepsin (Salt/Mix); Fenigramon (Salt/Mix); Soluble phenytoin (Salt/Mix); Tacosal (Salt/Mix); Epdantoin (Salt/Mix); Epileptin (Salt/Mix); Episar (Salt/Mix); Epsolin (Salt/Mix); Citrullamon (Salt/Mix); 5,5-Diphenyl-2,4-imidazolidinedione (phenytoin)
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Normal alkane RI, non-polar column, temperature ramp
Go To: Top, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
| Column type | Capillary | Packed | Packed |
|---|---|---|---|
| Active phase | DB-1 | OV-1 | SE-30 |
| Column length (m) | 15. | 2. | 2. |
| Carrier gas | He | ||
| Substrate | Gas Chrom P | Gas Chrom P | |
| Column diameter (mm) | 0.25 | ||
| Phase thickness (μm) | 0.25 | ||
| Tstart (C) | 130. | 150. | 150. |
| Tend (C) | 290. | 300. | 300. |
| Heat rate (K/min) | 10. | 5. | 5. |
| Initial hold (min) | 1. | ||
| Final hold (min) | 10. | ||
| I | 2292. | 2385. | 2310. |
| Reference | Sharp, 1987 | Marozzi, Gambaro, et al., 1982 | Marozzi, Gambaro, et al., 1982 |
| Comment | MSDC-RI | MSDC-RI | MSDC-RI |
References
Go To: Top, Normal alkane RI, non-polar column, temperature ramp, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Sharp, 1987
Sharp, M.E.,
A rapid screening procedure for acidic and neutral drugs in blood by high resolution gas chromatography,
J. Anal. Toxicol., 1987, 11, 1, 8-11, https://doi.org/10.1093/jat/11.1.8
. [all data]
Marozzi, Gambaro, et al., 1982
Marozzi, E.; Gambaro, V.; Saligari, E.; Mariani, R.; Lodi, F.,
Use of the retention index in gas chromatographic studies of drugs,
J. Anal. Toxicol., 1982, 6, 4, 185-192, https://doi.org/10.1093/jat/6.4.185
. [all data]
Notes
Go To: Top, Normal alkane RI, non-polar column, temperature ramp, References
- Symbols used in this document:
Tend Final temperature Tstart Initial temperature - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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