Glycine

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Gas phase thermochemistry data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein

Quantity Value Units Method Reference Comment
Δfgas-93.3 ± 1.1kcal/molCcrNgauv, Sabbah, et al., 1977 

Condensed phase thermochemistry data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein
DH - Eugene S. Domalski and Elizabeth D. Hearing

Quantity Value Units Method Reference Comment
Δfsolid-126.1 ± 0.1kcal/molCcbVasil'ev, Borodin, et al., 1991ALS
Δfsolid-126.34kcal/molCcrNgauv, Sabbah, et al., 1977ALS
Δfsolid-128.4kcal/molCcbHutchens, Cole, et al., 1963ALS
Δfsolid-126.32 ± 0.10kcal/molCcbHuffman, Fox, et al., 1937Author's hf298=-126.69 kcal/mol; ALS
Quantity Value Units Method Reference Comment
Δcsolid-233. ± 2.kcal/molAVGN/AAverage of 8 values; Individual data points
Quantity Value Units Method Reference Comment
solid,1 bar24.739cal/mol*KN/AHutchens, Cole, et al., 1960DH
solid,1 bar26.10cal/mol*KN/AParks, Huffman, et al., 1933Extrapolation below 90 K, 31.59 J/mol*K.; DH

Constant pressure heat capacity of solid

Cp,solid (cal/mol*K) Temperature (K) Reference Comment
23.298.Badelin, Kulikov, et al., 1990T = 298, 313, 333, 348 K.; DH
22.7298.Kulikov, Kozlov, et al., 1989T = 298 to 348 K.; DH
23.7298.15Spink and Wads, 1975DH
23.71298.15Hutchens, Cole, et al., 1960T = 11 to 305 K.; DH
24.020299.5Parks, Huffman, et al., 1933T = 93 to 300 K. Value is unsmoothed experimental datum.; DH

Reaction thermochemistry data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
B - John E. Bartmess
RCD - Robert C. Dunbar

Note: Please consider using the reaction search for this species. This page allows searching of all reactions involving this species. A general reaction search form is also available. Future versions of this site may rely on reaction search pages in place of the enumerated reaction displays seen below.

Individual Reactions

C2H4NO2- + Hydrogen cation = Glycine

By formula: C2H4NO2- + H+ = C2H5NO2

Quantity Value Units Method Reference Comment
Δr342.7 ± 2.2kcal/molCIDCJones, Bernier, et al., 2007gas phase; B
Δr341.6 ± 2.1kcal/molG+TSCaldwell, Renneboog, et al., 1989gas phase; B
Δr342.4 ± 2.1kcal/molG+TSLocke and McIver, 1983gas phase; B
Δr336.9 ± 1.4kcal/molEIAEMuftakhov, Vasil'ev, et al., 1999gas phase; B
Quantity Value Units Method Reference Comment
Δr334.7 ± 2.0kcal/molIMRECaldwell, Renneboog, et al., 1989gas phase; B
Δr335.5 ± 2.0kcal/molIMRELocke and McIver, 1983gas phase; B

Sodium ion (1+) + Glycine = (Sodium ion (1+) • Glycine)

By formula: Na+ + C2H5NO2 = (Na+ • C2H5NO2)

Quantity Value Units Method Reference Comment
Δr38.5 ± 1.9kcal/molCIDCKish, Ohanessian, et al., 2003Anchor alanine=39.89; RCD
Δr39.2 ± 1.4kcal/molCIDTMoision and Armentrout, 2002RCD
Δr36.6kcal/molCIDTKlassen, Anderson, et al., 1996RCD

Potassium ion (1+) + Glycine = (Potassium ion (1+) • Glycine)

By formula: K+ + C2H5NO2 = (K+ • C2H5NO2)

Quantity Value Units Method Reference Comment
Δr30.0kcal/molCIDTKlassen, Anderson, et al., 1996RCD

References

Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Reaction thermochemistry data, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Ngauv, Sabbah, et al., 1977
Ngauv, S.N.; Sabbah, R.; Laffitte, M., Thermodynamique de composes azotes. III. Etude thermochimique de la glycine et de la l-α-alanine, Thermochim. Acta, 1977, 20, 371-380. [all data]

Vasil'ev, Borodin, et al., 1991
Vasil'ev, V.P.; Borodin, V.A.; Kopnyshev, S.B., Calculation of the standard enthalpies of combustion and of formation of crystalline organic acids and complexones from the energy contributions of atomic groups, Russ. J. Phys. Chem. (Engl. Transl.), 1991, 65, 29-32. [all data]

Hutchens, Cole, et al., 1963
Hutchens, J.O.; Cole, A.G.; Stout, J.W., Heat capacities from 11 to 305°K., entropies, and free energies of formation of L-valine, L-isoleucine, and L-leucine, J. Phys. Chem., 1963, 67, 1128-1130. [all data]

Huffman, Fox, et al., 1937
Huffman, H.M.; Fox, S.W.; Ellis, E.L., Thermal data. VII. The heats of combustion of seven amino acids, J. Am. Chem. Soc., 1937, 59, 2144-21. [all data]

Hutchens, Cole, et al., 1960
Hutchens, J.O.; Cole, A.G.; Stout, J.W., Heat capacities from 11 to 305K. and entropies of L-alanine and glycine, J. Am. Chem. Soc., 1960, 82, 4813-4815. [all data]

Parks, Huffman, et al., 1933
Parks, G.S.; Huffman, H.M.; Barmore, M., Thermal data on organic compounds. XI. The heat capacities, entropies and free energies of ten compounds containing oxygen or nitrogen. J. Am. Chem. Soc., 1933, 55, 2733-2740. [all data]

Badelin, Kulikov, et al., 1990
Badelin, V.G.; Kulikov, O.V.; Batagin, V.S.; Udzig, E.; Zielenkiewicz, A.; Zielenkiewicz, W.; Krestov, G.A., Physico-chemical properties of peptides and their solutions, Thermochim. Acta, 1990, 169, 81-93. [all data]

Kulikov, Kozlov, et al., 1989
Kulikov, O.V.; Kozlov, V.A.; Malenkina, L.I.; Badelin, V.G., Heat capacities of amino acids and peptides and excess characteristics ot their aqueous solutions, Sbornik Nauch. Trud., Termodin. Rast. neelect., Ivanovo, Inst. nevod. rast., 1989, Akad. [all data]

Spink and Wads, 1975
Spink, C.H.; Wads, I., Thermochemistry of solutions of biochemical model compounds. 4. The partial molar heat capacities of some amino acids in aqueous solution, J. Chem. Thermodynam., 1975, 7, 561-572. [all data]

Jones, Bernier, et al., 2007
Jones, C.M.; Bernier, M.; Carson, E.; Colyer, K.E.; Metz, R.; Pawlow, A.; Wischow, E.D.; Webb, I.; Andriole, E.J.; Poutsma, J.C., Gas-phase Acities of the 20 Protein Amino Acids, Int. J. Mass Spectrom., 2007, 267, 1-3, 54-62, https://doi.org/10.1016/j.ijms.2007.02.018 . [all data]

Caldwell, Renneboog, et al., 1989
Caldwell, G.; Renneboog, R.; Kebarle, P., Gas Phase Acidities of Aliphatic Carboxylic Acids, Based on Measurements of Proton Transfer Equilibria, Can. J. Chem., 1989, 67, 4, 661, https://doi.org/10.1139/v89-092 . [all data]

Locke and McIver, 1983
Locke, M.J.; McIver, R.T., Jr., Effect of Solvation on the Acid/Base Properties of Glycine, J. Am. Chem. Soc., 1983, 105, 4226. [all data]

Muftakhov, Vasil'ev, et al., 1999
Muftakhov, M.V.; Vasil'ev, Y.V.; Mazunov, V.A., Determination of electron affinity of carbonyl radicals by means of negative ion mass spectrometry, Rapid Commun. Mass Spectrom., 1999, 13, 12, 1104-1108, https://doi.org/10.1002/(SICI)1097-0231(19990630)13:12<1104::AID-RCM619>3.0.CO;2-C . [all data]

Kish, Ohanessian, et al., 2003
Kish, M.M.; Ohanessian, G.; Wesdemiotis, C., The Na+ affinities of a-amino acids: side-chain substituent effects, Int. J. Mass Spectrom., 2003, 227, 3, 509, https://doi.org/10.1016/S1387-3806(03)00082-4 . [all data]

Moision and Armentrout, 2002
Moision, R.M.; Armentrout, P.B., Experimental and Theoretical Dissection of Sodium Cation/Glycine Interactions, J. Phys. Chem A, 2002, 106, 43, 10350, https://doi.org/10.1021/jp0216373 . [all data]

Klassen, Anderson, et al., 1996
Klassen, J.S.; Anderson, S.G.; Blades, A.T.; Kebarle, P., Reaction Enthalpies for M+L = M+ + L, Where M+ = Na+ and K+ and L = Acetamide, N-Methylacetamide, N,N-Dimethylacetamide, Glycine, and Glycylglycine, from Determinations of the Collision-Induced Dissociation Thresholds, J. Phys. Chem., 1996, 100, 33, 14218, https://doi.org/10.1021/jp9608382 . [all data]


Notes

Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Reaction thermochemistry data, References