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Imipramine


Gas phase ion energetics data

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
LLK - Sharon G. Lias, Rhoda D. Levin, and Sherif A. Kafafi
RDSH - Henry M. Rosenstock, Keith Draxl, Bruce W. Steiner, and John T. Herron

Ionization energy determinations

IE (eV) Method Reference Comment
8.21 ± 0.07CTSPoltorakov, Pirnazarova, et al., 1973LLK
7.35 ± 0.05CTSFulton and Lyons, 1968RDSH
8.03CTSSlifkin and Allison, 1967RDSH

Mass spectrum (electron ionization)

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Spectrum

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Mass spectrum
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Additional Data

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Owner NIST Mass Spectrometry Data Center
Collection (C) 2014 copyright by the U.S. Secretary of Commerce
on behalf of the United States of America. All rights reserved.
Origin Virginia Division of Forensic Science
NIST MS number 250696

All mass spectra in this site (plus many more) are available from the NIST/EPA/NIH Mass Spectral Library. Please see the following for information about the library and its accompanying search program.


UV/Visible spectrum

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: Victor Talrose, Alexander N. Yermakov, Alexy A. Usov, Antonina A. Goncharova, Axlexander N. Leskin, Natalia A. Messineva, Natalia V. Trusova, Margarita V. Efimkina

Spectrum

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UVVis spectrum
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1.) Enter the desired X axis range (e.g., 100, 200)
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Additional Data

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Source Lang (editor), 1965
Owner INEP CP RAS, NIST OSRD
Collection (C) 2007 copyright by the U.S. Secretary of Commerce
on behalf of the United States of America. All rights reserved.
Origin INSTITUTE OF ENERGY PROBLEMS OF CHEMICAL PHYSICS, RAS
Source reference RAS UV No. 19647
Instrument Hilger Uvispek
Melting point 172-173

Gas Chromatography

Go To: Top, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Kovats' RI, non-polar column, isothermal

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Column type Active phase Temperature (C) I Reference Comment
CapillaryDB-1275.2262.Japp, Gill, et al., 198730. m/0.53 mm/1.5 «mu»m, N2
PackedSE-30220.2212.Musumarra, Scarlata, et al., 1987N2, 1% se-30 on Anachrom ABS(80-100mesh); Column length: 2. m
CapillarySPB-1250.2262.Lora-Tamayo, Rams, et al., 1986He; Column length: 25. m; Column diameter: 0.20 mm
PackedOV-1200.2210.Berninger and Möller, 1977 

Kovats' RI, non-polar column, temperature ramp

View large format table.

Column type Active phase I Reference Comment
CapillarySE-302222.Schepers, Wijsbeek, et al., 198225. m/0.49 mm/1.14 «mu»m, 100. C @ 2. min, 8. K/min, 275. C @ 15. min

Kovats' RI, non-polar column, custom temperature program

View large format table.

Column type Active phase I Reference Comment
PackedOV-1012240.McLinden and Stenhouse, 1979N2, Chromosorb W; Column length: 2. m; Program: not specified

Van Den Dool and Kratz RI, non-polar column, temperature ramp

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Column type Active phase I Reference Comment
CapillaryVF-5MS2282.3Tretyakov, 201430. m/0.25 mm/0.25 «mu»m, He; Tstart: 60. C; Tend: 270. C
CapillarySPB-12226.Christ, Noomano, et al., 198830. m/0.75 mm/1.0 «mu»m, He, 10. K/min, 280. C @ 12. min; Tstart: 160. C
PackedMethyl Silicone2205.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2219.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2218.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2220.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2220.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2220.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2222.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2225.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2225.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2225.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2225.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2228.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2228.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2230.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2220.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2220.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2222.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2223.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2223.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2223.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2223.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2223.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2225.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2233.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2230.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2230.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2230.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2232.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2232.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2232.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2232.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2235.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2235.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2235.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2240.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
PackedMethyl Silicone2242.Bogusz, Wijsbeek, et al., 1985120. C @ 4. min, 7. K/min, 290. C @ 10. min
CapillaryDB-12205.Perrigo, Peel, et al., 198515. m/0.32 mm/0.25 «mu»m, He, 8. K/min, 280. C @ 5. min; Tstart: 120. C
CapillaryDB-12205.Perrigo, Ballantyne, et al., 198415. m/0.25 mm/0.25 «mu»m, He, 8. K/min, 280. C @ 5. min; Tstart: 120. C
CapillarySE-302190.Anderson and Stafford, 198315. m/0.25 mm/0.25 «mu»m, He, 5. K/min; Tstart: 100. C; Tend: 295. C
PackedSE-302215.Perrigo and Peel, 1981N2, Chromosorb W, 130. C @ 2. min, 8. K/min, 290. C @ 8. min; Column length: 1.8 m

Normal alkane RI, non-polar column, isothermal

View large format table.

Column type Active phase Temperature (C) I Reference Comment
PackedOV-101180.2208.Dubsky, Hána, et al., 1978Nitrogen, Chromosorb G (100-120 mesh); Column length: 2. m
PackedOV-101200.2210.Dubsky, Hána, et al., 1978Nitrogen, Chromosorb G (100-120 mesh); Column length: 2. m

Normal alkane RI, non-polar column, temperature ramp

View large format table.

Column type Active phase I Reference Comment
CapillaryDB-52192.Phillips, Logan, et al., 199015. m/0.25 mm/0.2 «mu»m, He, 10. K/min; Tstart: 185. C; Tend: 270. C
PackedOV-12260.Marozzi, Gambaro, et al., 1982Gas Chrom P, 5. K/min; Column length: 2. m; Tstart: 150. C; Tend: 300. C
PackedSE-302240.Marozzi, Gambaro, et al., 1982Gas Chrom P, 5. K/min; Column length: 2. m; Tstart: 150. C; Tend: 300. C
PackedSE-302215.Peel and Perrigo, 1976Nitrogen, Chromosorb W AW DMS (80-100 mesh), 130. C @ 2. min, 8. K/min, 290. C @ 8. min; Column length: 2. m
PackedSE-302215.Peel and Perrigo, 1975N2, Chromosorb W AW DMS, 130. C @ 2. min, 8. K/min, 290. C @ 8. min; Column length: 2. m

Normal alkane RI, non-polar column, custom temperature program

View large format table.

Column type Active phase I Reference Comment
PackedOV-1012214.Maurer and Pfleger, 1984Program: not specified
OtherMethyl Silicone2223.Ardrey and Moffat, 1981Program: not specified
PackedOV-1012212.Dubsky, Hána, et al., 1978Nitrogen, Chromosorb G (100-120 mesh); Column length: 2. m; Program: not specified
PackedOV-1012220.Dubsky, Hána, et al., 1978Nitrogen, Chromosorb G (100-120 mesh); Column length: 2. m; Program: not specified

References

Go To: Top, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, Gas Chromatography, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Poltorakov, Pirnazarova, et al., 1973
Poltorakov, A.P.; Pirnazarova, F.N.; But, P.G.; Piruzyan, L.A.; Chibrikin, V.M.; Vikjlyaev, Yu.I.; Ul'yanova, O.V., Ionization potentials of phenothiazine derivatives and their correlation with the parmacologic effect, Bull. Acad. Sci. USSR, Div. Chem. Sci., 1973, 22, 2050, In original 2106. [all data]

Fulton and Lyons, 1968
Fulton, A.; Lyons, L.E., The ionization energies of some phenothiazine tranquillizers and molecules of similar structure, Australian J. Chem., 1968, 21, 873. [all data]

Slifkin and Allison, 1967
Slifkin, M.A.; Allison, A.C., Measurement of ionization potentials from contact charge transfer spectra, Nature, 1967, 215, 949. [all data]

Lang (editor), 1965
Lang (editor), L., Absorption Spectra in the Ultraviolet and Visible Region, 1965, 5, 349. [all data]

Japp, Gill, et al., 1987
Japp, M.; Gill, R.; Osselton, M.D., Comparison of drug retention indices determined on packed, wide bore capillary and narrow bore capillary columns, J. Forensic Sci., 1987, 32, 6, 1574-1586. [all data]

Musumarra, Scarlata, et al., 1987
Musumarra, G.; Scarlata, G.; Romano, G.; Cappello, G.; Clementi, S.; Giulietti, G., Qualitative organic analysis. Part 2. Identification of drugs by principal components analysis of standardized TLC data in four eluent systems and of retention indices on SE 30, J. Anal. Toxicol., 1987, 11, 4, 154-163, https://doi.org/10.1093/jat/11.4.154 . [all data]

Lora-Tamayo, Rams, et al., 1986
Lora-Tamayo, C.; Rams, M.A.; Chacon, J.M.R., Gas Chromatographic Data for 187 Nitrogen- or Phosphorus-Containing Drugs and Metabolites of Toxicological Interest Analysed on Methyl Silicone Capillary Columns, J. Chromatogr., 1986, 374, 73-85, https://doi.org/10.1016/S0378-4347(00)83254-5 . [all data]

Berninger and Möller, 1977
Berninger, H.; Möller, M.R., Retentionsindices zur gaschromatographischen Identifizierung von Arzneimitteln, Arch. Toxicol., 1977, 37, 4, 295-305, https://doi.org/10.1007/BF00330821 . [all data]

Schepers, Wijsbeek, et al., 1982
Schepers, P.; Wijsbeek, J.; Franke, J.P.; de Zeeuw, R.A., Applicability of capillary gas chromatography to substance identification in toxicology by means of retention indices, J. Forensic Sci., 1982, 27, 1, 49-60. [all data]

McLinden and Stenhouse, 1979
McLinden, V.J.; Stenhouse, A.M., A chromatography system for drug identification, Forensic Sci. Int., 1979, 13, 71-79, https://doi.org/10.1016/0379-0738(79)90265-2 . [all data]

Tretyakov, 2014
Tretyakov, K.V., Retention Data. NIST Mass Spectrometry Data Center., NIST Mass Spectrometry Data Center, 2014. [all data]

Christ, Noomano, et al., 1988
Christ, D.W.; Noomano, P.; Rosas, M.; Rhone, D., Retention indices by wide-bore capillary gas chromatography with nitrogen-phosphorus detection, J. Anal. Toxicol., 1988, 12, 2, 84-88, https://doi.org/10.1093/jat/12.2.84 . [all data]

Bogusz, Wijsbeek, et al., 1985
Bogusz, M.; Wijsbeek, J.; Franke, J.P.; de Zeeuw, R.A.; Gierz, J., Impact of biological matrix, drug concentration, and method of isolation on detectability and variability of retention index values in gas chromatography, J. Anal. Toxicol., 1985, 9, 2, 49-54, https://doi.org/10.1093/jat/9.2.49 . [all data]

Perrigo, Peel, et al., 1985
Perrigo, B.J.; Peel, H.W.; Ballantyne, D.J., Use of Dual-Column Fused-Silica Capillary Gas Chromatography in Combination with Detector Response Factors for Analytical Toxicology., J. Chromatogr., 1985, 341, 81-88, https://doi.org/10.1016/S0378-4347(00)84011-6 . [all data]

Perrigo, Ballantyne, et al., 1984
Perrigo, B.J.; Ballantyne, D.J.; Peel, H.W., Condierations in developing a data base for drugs on a DBI capillary column, J. Can. Soc. Forensic Sci., 1984, 17, 2, 41-49, https://doi.org/10.1080/00085030.1984.10757360 . [all data]

Anderson and Stafford, 1983
Anderson, W.H.; Stafford, D.T., Applications of capillary gas chromatography in routine toxicological analyses, J. Hi. Res. Chromatogr. Chromatogr. Comm., 1983, 6, 5, 247-254, https://doi.org/10.1002/jhrc.1240060506 . [all data]

Perrigo and Peel, 1981
Perrigo, B.J.; Peel, H.W., The use of retention indices and temperature-programmed gas chromatography in analytical toxicology, J. Chromatogr. Sci., 1981, 19, 5, 219-226, https://doi.org/10.1093/chromsci/19.5.219 . [all data]

Dubsky, Hána, et al., 1978
Dubsky, H.; Hána, K.; Komárková, M.; Rittich, B., Pouzití kovatsovych indexu pri toxikologickych analysách, Chem. Listy, 1978, 72, 980-984. [all data]

Phillips, Logan, et al., 1990
Phillips, A.M.; Logan, B.K.; Stafford, D.T., Further applications for capillary gas chromatography in routine quantitative toxicological analyses, J. Hi. Res. Chromatogr., 1990, 13, 11, 754-758, https://doi.org/10.1002/jhrc.1240131106 . [all data]

Marozzi, Gambaro, et al., 1982
Marozzi, E.; Gambaro, V.; Saligari, E.; Mariani, R.; Lodi, F., Use of the retention index in gas chromatographic studies of drugs, J. Anal. Toxicol., 1982, 6, 4, 185-192, https://doi.org/10.1093/jat/6.4.185 . [all data]

Peel and Perrigo, 1976
Peel, H.W.; Perrigo, B., A practical gas chromatographic screening procedure for toxicological analysis, Can. Soc. Forens. Sci. J., 1976, 9, 2, 69-74, https://doi.org/10.1080/00085030.1976.10757247 . [all data]

Peel and Perrigo, 1975
Peel, H.W.; Perrigo, B., A practical gas chromatographic screening procedure for toxicological analysis, Can.Soc.Forens.Sci.J., 1975, 9, 2, 69-74, https://doi.org/10.1080/00085030.1976.10757247 . [all data]

Maurer and Pfleger, 1984
Maurer, H.; Pfleger, K., Screening procedure for detection of antidepressants and their metabolites in urine using a computerized gas chromatographic-mass spectrometric technique, J. Chromatogr., 1984, 305, 309-323, https://doi.org/10.1016/S0378-4347(00)83345-9 . [all data]

Ardrey and Moffat, 1981
Ardrey, R.E.; Moffat, A.C., Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase, J. Chromatogr., 1981, 220, 3, 195-252, https://doi.org/10.1016/S0021-9673(00)81925-1 . [all data]


Notes

Go To: Top, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, Gas Chromatography, References