Amitriptyline
- Formula: C20H23N
- Molecular weight: 277.4033
- IUPAC Standard InChI: InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3
- IUPAC Standard InChIKey: KRMDCWKBEZIMAB-UHFFFAOYSA-N
- CAS Registry Number: 50-48-6
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Other names: 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-; 5H-Dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-; Adepress; Adepril; Amitriptylin; Damilen; Damitriptyline; Elavil; Flavyl; Lantron; Proheptadiene; Ro 4-1575; Seroten; Triptanol; Triptisol; Tryptanol; 5-(γ-Dimethylaminopropylidene)-5H-Dibenzo[a,d][1,4]cycloheptadiene; Damilan; 3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine; 10,11-Dihydro-5-(γ-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene; 10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Δ5,γ-propylamine; 5-(3'-Dimethylaminopropylidene)-dibenzo-(a,d)(1,4)-cycloheptadiene; 5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene; 5-(γ-Dimethylaminopropylidene)-5H-dibenzo(a,d)-10,11-dihydrocycloheptene; 5-(γ-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene; Elanil; 5-(γ-Dimethylaminopropylidine)-5H-dibenzo(a,d)(1,4)cycloheptadiene; Amitryptiline; Laroxyl; Lentizol; Triptizol; Vanatrip; Domical
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Van Den Dool and Kratz RI, non-polar column, custom temperature program
Go To: Top, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
| Column type | Capillary | Capillary |
|---|---|---|
| Active phase | CP Sil 5 CB | BP-1 |
| Column length (m) | 10. | 12. |
| Carrier gas | He | He |
| Substrate | ||
| Column diameter (mm) | 0.53 | 0.22 |
| Phase thickness (μm) | 5.0 | 0.25 |
| Program | 100 0C (2 min ) 15 0C/min -> 200 0C 10 0C/min -> 300 0C (8 min hold) | 120C => 8C/min => 270C => 25C/min => 300C |
| I | 2208. | 2181. |
| Reference | Aderjan and Bogusz, 1988 | Stowell and Wilson, 1987 |
| Comment | MSDC-RI | MSDC-RI |
References
Go To: Top, Van Den Dool and Kratz RI, non-polar column, custom temperature program, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Aderjan and Bogusz, 1988
Aderjan, R.; Bogusz, M.,
Nitroalkanes as a multidetector retention index scale for drug identification in gas chromatography,
J. Chromatogr., 1988, 454, 345-351, https://doi.org/10.1016/S0021-9673(00)88629-X
. [all data]
Stowell and Wilson, 1987
Stowell, A.; Wilson, L.W.,
A simple approach to the interlaboratory transfer of drug retention indices determined by temperature programmed capillary gas chromatography,
J. Forensic Sci., 1987, 32, 5, 1214-1220. [all data]
Notes
Go To: Top, Van Den Dool and Kratz RI, non-polar column, custom temperature program, References
- Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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