Estradiol

• Formula: C₁₈H₂₄O₂
• Molecular weight: 272.3820
• IUPAC Standard InChI: InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14?,15?,16?,17-,18?/m1/s1 Copy

  
• IUPAC Standard InChIKey: VOXZDWNPVJITMN-AWDGRILASA-N Copy
• CAS Registry Number: 50-28-2
• Chemical structure:
  This structure is also available as a 2d Mol file or as a computed 3d SD file
  The 3d structure may be viewed using Java or Javascript.
• Stereoisomers:
  • α-Estradiol
• Other names: Estra-1,3,5(10)-triene-3,17-diol (17β)-; β-Estradiol; Altrad; Aquadiol; Bardiol; Corpagen; D-3,17β-Estradiol; Dihydrofollicular hormone; Dihydrofolliculin; Dihydromenformon; Dihydrotheelin; Dihydroxyestrin; Dimenformon; Diogyn; Diogynets; Estra-1,3,5(10)-triene-3,17β-diol; Estraldine; Estrovite; Femestral; Femogen; Follicyclin; Ginosedol; Gynergon; Gynoestryl; Lamdiol; Macrodiol; Nordicol; Oestergon; Oestra-1,3,5(10)-triene-3,17β-diol; Oestradiol; Oestroglandol; Ovahormon; Ovasterol; Ovastevol; Ovocyclin; Perlatanol; Primofol; Profoliol; Progynon; Progynon-DH; Syndiol; Theelin, dihydro-; 17β-Estradiol; 17β-Oestradiol; 3,17β-Dihydroxyestra-1,3,5(10)-triene; 3,17β-Dihydroxyestra-1,3,5-triene; 3,17β-Estradiol; 3,17-Epidihydroxyestratriene; 1,3,5,(10)-Estratrien-3,17β-diol; β-Oestradiol; cis-Estradiol; cis-Oestradiol; D-Estradiol; D-Oestradiol; D-3,17β-Oestradiol; Dihydroxyesterin; Dihydroxyoestrin; Dimenformon prolongatum; Estrace; Estradiol-17β; Estradiol, β-; Menest; NSC-9895; Oestradiol-17β; Ovocycline; Ovocylin; SK-Estrogens; Trocosone; 1,3,5-Estratriene-3,17β-diol; 17β-Estra-1,3,5(10)-triene-3,17-diol; 17β-Oestra-1,3,5(10)-triene-3,17-diol; 17β-OH-estradiol; 17β-OH-oestradiol; 3,17β-Dihydroxy-1,3,5(10)-estratriene; 3,17β-Dihydroxy-1,3,5(10)-oestratriene; 3,17β-Dihydroxyoestra-1,3,5-triene; 3,17-Epidihydroxyoestratriene; E 2; Gynestrel; Macrol; Microdiol; 3,17-β-Oestradiol; Oestradiol R; Oestrogynal; Ovociclina; Estraderm TTS; Climara; Estraderm; Estring vaginal ring; Estroclim; Evorel; Menorest; NSC-20293; Oestrogel; Profoliol B; Systen; Vagifem; Vivelle; Zumenon; Oesclim; (+)-3,17β-Estradiol; Beta-estradiol; Benzogynestry; Epiestriol 50; Estasorb; Femanest; Estropause; Gelestra; Estradot; α-Estradiol; α-Oestradiol; component of Menrium; Amnestrogen; Estrol; Evex; Femestrol; E(sub 2); Agofollin; Soldep; Ricifon; Sotipox; Ritsifon; 3,17-Epidihydroxyestratrienelor; Estra-1(10),2,4-triene-3,17-diol; Estra-1,3,5(10)-triene-3,17beta-diol
• Permanent link for this species. Use this link for bookmarking this species for future reference.
• Information on this page:
  • Reaction thermochemistry data
  • References
  • Notes
• Other data available:
  • Phase change data
  • Gas phase ion energetics data
  • IR Spectrum
  • Mass spectrum (electron ionization)
  • Gas Chromatography
• Options:
  • Switch to calorie-based units

Data at NIST subscription sites:

• NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data)

NIST subscription sites provide data under the NIST Standard Reference Data Program, but require an annual fee to access. The purpose of the fee is to recover costs associated with the development of data collections included in such sites. Your institution may already be a subscriber. Follow the links above to find out more about the data in these sites and their terms of usage.

Reaction thermochemistry data

Go To: Top, References, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: John E. Bartmess

Note: Please consider using the reaction search for this species. This page allows searching of all reactions involving this species. A general reaction search form is also available. Future versions of this site may rely on reaction search pages in place of the enumerated reaction displays seen below.

Individual Reactions

C₁₈H₂₃O₂^- +  =

By formula: C₁₈H₂₃O₂^- + H⁺ = C₁₈H₂₄O₂

References

Go To: Top, Reaction thermochemistry data, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Bourgoin-Voillard, Zins, et al., 2009
Bourgoin-Voillard, S.; Zins, E.L.; Fournier, F.; Jacquot, Y.; Afonso, C.; Pepe, C.; Leclercq, G.; Tabet, J.C., Stereochemical Effects During [M-H](-) Dissociations of Epimeric 11-OH-17 beta-Estradiols and Distant Electronic Effects of Substituents at C-(11) Position on Gas Phase Acidity, J. Am. Soc. Mass Spectrom., 2009, 20, 12, 2318-2333, https://doi.org/10.1016/j.jasms.2009.08.017 . [all data]

Notes

Go To: Top, Reaction thermochemistry data, References

• Symbols used in this document:
  

  ΔrG°	Free energy of reaction at standard conditions
  ΔrH°	Enthalpy of reaction at standard conditions

• Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
• The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database.
• Customer support for NIST Standard Reference Data products.