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Niflumic acid

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Phase change data

Go To: Top, Mass spectrum (electron ionization), Gas Chromatography, References, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled as indicated in comments:
TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Kenneth Kroenlein director
AC - William E. Acree, Jr., James S. Chickos

Quantity Value Units Method Reference Comment
Tfus476.0KN/APinvidic, Gonthier-Vassal, et al., 1989Uncertainty assigned by TRC = 0.1 K; TRC
Quantity Value Units Method Reference Comment
Deltavap25.69kcal/molS-FPerlovich, Surov, et al., 2007AC
Quantity Value Units Method Reference Comment
Deltasub31.1 ± 0.2kcal/molGSPerlovich, Surov, et al., 2007Based on data from 355. - 396. K. See also Surov, Terekhova, et al., 2009.; AC

Enthalpy of sublimation

DeltasubH (kcal/mol) Temperature (K) Method Reference Comment
30.5 ± 0.2376.GSPerlovich, Surov, et al., 2007Based on data from 355. - 396. K. See also Surov, Terekhova, et al., 2009.; AC

Enthalpy of fusion

DeltafusH (kcal/mol) Temperature (K) Method Reference Comment
8.72478.DSCPerlovich, Surov, et al., 2007See also Surov, Terekhova, et al., 2009.; AC
8.53476.4DSCRomero, Bustamante, et al., 2004AC
7.823477.2N/ABustamante, Peña, et al., 1998AC
9.08476.N/APinvidic, Gonthier-Vassal, et al., 1989AC

In addition to the Thermodynamics Research Center (TRC) data available from this site, much more physical and chemical property data is available from the following TRC products:


Mass spectrum (electron ionization)

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Spectrum

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Mass spectrum
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Additional Data

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Owner NIST Mass Spectrometry Data Center
Collection (C) 2014 copyright by the U.S. Secretary of Commerce
on behalf of the United States of America. All rights reserved.
Origin Patti Price, Georgia Bureau of Investigation, Decatur, Georgia
NIST MS number 248468

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Gas Chromatography

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Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director

Kovats' RI, non-polar column, isothermal

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Column type Active phase Temperature (C) I Reference Comment
CapillarySPB-1250.2093.Lora-Tamayo, Rams, et al., 1986He; Column length: 25. m; Column diameter: 0.20 mm

References

Go To: Top, Phase change data, Mass spectrum (electron ionization), Gas Chromatography, Notes

Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.

Pinvidic, Gonthier-Vassal, et al., 1989
Pinvidic, J.J.; Gonthier-Vassal, A.; Szwarc, H.; Ceolin, R.; Toffoli, P.; Teulon, J.M.; Guechot, C., Niflumic acid-morniflumate phase diagram: 1. Study of the components, Thermochim. Acta, 1989, 153, 37-45. [all data]

Perlovich, Surov, et al., 2007
Perlovich, German L.; Surov, Artem O.; Bauer-Brandl, Annette, Thermodynamic properties of flufenamic and niflumic acids---Specific and non-specific interactions in solution and in crystal lattices, mechanism of solvation, partitioning and distribution, Journal of Pharmaceutical and Biomedical Analysis, 2007, 45, 4, 679-687, https://doi.org/10.1016/j.jpba.2007.01.039 . [all data]

Surov, Terekhova, et al., 2009
Surov, Artem O.; Terekhova, Irina V.; Bauer-Brandl, Annette; Perlovich, German L., Thermodynamic and Structural Aspects of Some Fenamate Molecular Crystals, Crystal Growth & Design, 2009, 9, 7, 3265-3272, https://doi.org/10.1021/cg900002q . [all data]

Romero, Bustamante, et al., 2004
Romero, S.; Bustamante, P.; Escalera, B.; Cirri, M.; Mura, P., Characterization of the solid phases of paracetamol and fenamates at equilibrium in saturated solutions, Journal of Thermal Analysis and Calorimetry, 2004, 77, 2, 541-554, https://doi.org/10.1023/B:JTAN.0000038993.61782.ba . [all data]

Bustamante, Peña, et al., 1998
Bustamante, P.; Peña, M.A.; Barra, J., Partial solubility parameters of piroxicam and niflumic acid, International Journal of Pharmaceutics, 1998, 174, 1-2, 141-150, https://doi.org/10.1016/S0378-5173(98)00263-4 . [all data]

Lora-Tamayo, Rams, et al., 1986
Lora-Tamayo, C.; Rams, M.A.; Chacon, J.M.R., Gas Chromatographic Data for 187 Nitrogen- or Phosphorus-Containing Drugs and Metabolites of Toxicological Interest Analysed on Methyl Silicone Capillary Columns, J. Chromatogr., 1986, 374, 73-85, https://doi.org/10.1016/S0378-4347(00)83254-5 . [all data]


Notes

Go To: Top, Phase change data, Mass spectrum (electron ionization), Gas Chromatography, References