Pyrazine, 2-ethyl-6-methyl-
- Formula: C7H10N2
- Molecular weight: 122.1677
- IUPAC Standard InChIKey: RAFHQTNQEZECFL-UHFFFAOYSA-N
- CAS Registry Number: 13925-03-6
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Other names: 2-Ethyl-6-methylpyrazine; 2-Methyl-6-ethylpyrazine; 2,6-Methylethylpyrazine; Pyrazine, 6-ethyl-2-methyl
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- Other data available:
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Normal alkane RI, non-polar column, temperature ramp
Go To: Top, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
Column type | Capillary | Capillary | Capillary | Capillary | Capillary |
---|---|---|---|---|---|
Active phase | HP-5 MS | Ultra-1 | HP-5 | SLB-5MS | DB-5 |
Column length (m) | 30. | 50. | 50. | 10. | 60. |
Carrier gas | Helium | Helium | Helium | Helium | He |
Substrate | |||||
Column diameter (mm) | 0.25 | 0.20 | 0.20 | 0.18 | 0.32 |
Phase thickness (μm) | 0.25 | 0.33 | 0.33 | 0.18 | |
Tstart (C) | 70. | 50. | 50. | 40. | 50. |
Tend (C) | 290. | 280. | 280. | 295. | 250. |
Heat rate (K/min) | 5. | 2. | 10. | 10. | 4. |
Initial hold (min) | 1.5 | 5. | |||
Final hold (min) | 10. | 20. | 8.5 | ||
I | 1001. | 970. | 998. | 1014. | 994. |
Reference | Radulovic, Blagojevic, et al., 2010 | Du, Clery, et al., 2008 | Du, Clery, et al., 2008 | Risticevic, Carasek, et al., 2008 | Fadel, Mageed, et al., 2006 |
Comment | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI |
Column type | Capillary | Capillary | Capillary | Capillary | Capillary |
---|---|---|---|---|---|
Active phase | HP-5 | MDN-5 | DB-5MS | DB-5MS | DB-1 |
Column length (m) | 60. | 60. | 30. | 50. | 60. |
Carrier gas | He | He | He | He | He |
Substrate | |||||
Column diameter (mm) | 0.32 | 0.25 | 0.53 | 0.25 | 0.32 |
Phase thickness (μm) | 0.25 | 0.25 | 1.5 | 1. | |
Tstart (C) | 30. | 40. | 40. | 40. | 40. |
Tend (C) | 260. | 270. | 225. | 220. | 260. |
Heat rate (K/min) | 2. | 4. | 6. | 5. | 2. |
Initial hold (min) | 2. | 4. | 5. | 5. | |
Final hold (min) | 28. | 5. | 30. | 5. | |
I | 1003.0 | 1000. | 995. | 1006. | 988. |
Reference | Leffingwell and Alford, 2005 | van Loon, Linssen, et al., 2005 | Cadwallader and Heo, 2001 | Welty, Marshall, et al., 2001 | Chen and Ho, 1999 |
Comment | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI |
Column type | Capillary | Capillary | Capillary | Capillary | Capillary |
---|---|---|---|---|---|
Active phase | HP-5 | DB-1 | DB-1 | DB-1 | DB-1 |
Column length (m) | 50. | 60. | 60. | 60. | 60. |
Carrier gas | He | He | He | ||
Substrate | |||||
Column diameter (mm) | 0.32 | 0.32 | 0.32 | 0.25 | 0.32 |
Phase thickness (μm) | 0.52 | 1.0 | 1. | 1. | |
Tstart (C) | 35. | 40. | 40. | 30. | 40. |
Tend (C) | 250. | 260. | 260. | 200. | 280. |
Heat rate (K/min) | 2. | 2. | 3. | 4. | 2. |
Initial hold (min) | 15. | 25. | 2. | ||
Final hold (min) | 45. | 20. | 40. | ||
I | 997. | 988. | 967. | 973. | 977. |
Reference | Boylston and Viniyard, 1998 | Chen and Ho, 1998 | Chen, Wang, et al., 1998 | Buttery, Ling, et al., 1997 | Lu, Yu, et al., 1997 |
Comment | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI |
Column type | Capillary | Capillary | Capillary | Capillary | Capillary |
---|---|---|---|---|---|
Active phase | DB-1 | DB-1 | DB-1 | DB-1 | DB-1 |
Column length (m) | 60. | 60. | 60. | 60. | 60. |
Carrier gas | He | He | He | ||
Substrate | |||||
Column diameter (mm) | 0.25 | 0.25 | 0.25 | 0.32 | 0.32 |
Phase thickness (μm) | 1. | 0.25 | 0.25 | 0.25 | 0.25 |
Tstart (C) | 40. | 50. | 50. | 50. | 50. |
Tend (C) | 260. | 240. | 240. | 250. | 250. |
Heat rate (K/min) | 2. | 3. | 3. | 4. | 4. |
Initial hold (min) | 5. | 5. | 5. | ||
Final hold (min) | 60. | ||||
I | 984. | 959. | 960. | 969. | 970. |
Reference | Yu, Wu, et al., 1994 | Ishihara, Tsuneya, et al., 1992 | Ishihara, Tsuneya, et al., 1992 | Flath, Matsumoto, et al., 1989 | Flath, Matsumoto, et al., 1989 |
Comment | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI |
Column type | Capillary | Capillary | Capillary | Capillary | Capillary |
---|---|---|---|---|---|
Active phase | DB-1 | DB-1 | OV-101 | OV-101 | OV-1 |
Column length (m) | 60. | 60. | 50. | 50. | 50. |
Carrier gas | N2 | Hydrogen | |||
Substrate | |||||
Column diameter (mm) | 0.32 | 0.32 | 0.22 | 0.22 | 0.20 |
Phase thickness (μm) | 0.25 | 0.25 | |||
Tstart (C) | 50. | 50. | 80. | 80. | 50. |
Tend (C) | 250. | 250. | 200. | 200. | 200. |
Heat rate (K/min) | 4. | 4. | 2. | 2. | 1. |
Initial hold (min) | |||||
Final hold (min) | 35. | ||||
I | 971. | 971. | 977. | 977. | 986. |
Reference | Flath, Matsumoto, et al., 1989 | Flath, Matsumoto, et al., 1989 | Mihara and Masuda, 1988 | Mihara and Masuda, 1987 | Wu, Liou, et al., 1987 |
Comment | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI |
Column type | Capillary | Capillary | Capillary |
---|---|---|---|
Active phase | DB-5 | OV-101 | OV-101 |
Column length (m) | 60. | 50. | 50. |
Carrier gas | H2 | N2 | He |
Substrate | |||
Column diameter (mm) | 0.32 | 0.22 | 0.31 |
Phase thickness (μm) | |||
Tstart (C) | 40. | 80. | 0. |
Tend (C) | 200. | 200. | 225. |
Heat rate (K/min) | 2. | 2. | 3. |
Initial hold (min) | 1. | ||
Final hold (min) | |||
I | 1001. | 977. | 969. |
Reference | Gallois and Grimont, 1985 | Mihara and Enomoto, 1985 | del Rosario, de Lumen, et al., 1984 |
Comment | MSDC-RI | MSDC-RI | MSDC-RI |
References
Go To: Top, Normal alkane RI, non-polar column, temperature ramp, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Radulovic, Blagojevic, et al., 2010
Radulovic, N.; Blagojevic, P.; Palic, R.,
Comparative study of the leaf volatiles of Arctostaphylos uva-ursi (L.) Spreng. and Vaccinium vitis-idaea L. (Ericaceae),
Molecules, 2010, 15, 9, 6168-6185, https://doi.org/10.3390/molecules15096168
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Du, Clery, et al., 2008
Du, Z.; Clery, R.; Hammond, C.J.,
Volatile organic nitrogen-containing constituents in ambrette seed Abelmoschus moschatus Medik (Malvaceae),
J. Agric. Food Chem., 2008, 56, 16, 7388-7392, https://doi.org/10.1021/jf800958d
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Risticevic, Carasek, et al., 2008
Risticevic, S.; Carasek, E.; Pawliszyn, J.,
Headspace solid-phase microextraction-gas chromatographic-time-of-flight mass spectrometric methodology for geographical origin verification of coffee,
Anal. Chim. Acta, 2008, 617, 1-2, 72-84, https://doi.org/10.1016/j.aca.2008.04.009
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Fadel, Mageed, et al., 2006
Fadel, H.H.M.; Mageed, M.A.A.; Samad, A.K.M.E.A.; Lotfy, S.N.,
Cocoa substitute: Evaluation of sensory qualities and flavour stability,
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Leffingwell and Alford, 2005
Leffingwell, J.C.; Alford, E.D.,
Volatile constituents of Perique tobacco,
Electron. J. Environ. Agric. Food Chem., 2005, 4, 2, 899-915. [all data]
van Loon, Linssen, et al., 2005
van Loon, W.A.M.; Linssen, J.P.H.; Legger, A.; Posthumus, M.A.; Voragen, A.G.J.,
Identification and olfactometry of French fries flavour extracted at mouth conditions,
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Cadwallader and Heo, 2001
Cadwallader, K.R.; Heo, J.,
Aroma of roasted sesame oil: characterization by direct thermal desorption-gas chromatography-olfactometry and sample dilution analysis,
Am. Chem. Soc. Symp. Ser., 2001, 782, 187-202. [all data]
Welty, Marshall, et al., 2001
Welty, W.M.; Marshall, R.T.; Grün, I.U.; Ellersieck, M.R.,
Effects of Milk Fat, Cocoa Butter, or Selected Fat Replacers on Flavor Volatiles of Chocolate Ice Cream,
J. Dairy Sci., 2001, 84, 1, 21-30, https://doi.org/10.3168/jds.S0022-0302(01)74447-5
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Chen and Ho, 1999
Chen, J.; Ho, C.-T.,
Comparison of volatile generation in serine/threonine/glutamine-ribose/glucose/fructose model systems,
J. Agric. Food Chem., 1999, 47, 2, 643-647, https://doi.org/10.1021/jf980771a
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Boylston and Viniyard, 1998
Boylston, T.D.; Viniyard, B.T.,
Isolation of volatile flavor compounds from peanut butter using purge-and-trap technique
in Instrumental Methods in Food and Beverage Analysis, D. Wetzel and G. Charalambous, ed(s)., 1998, 225-243. [all data]
Chen and Ho, 1998
Chen, J.; Ho, C.-T.,
Volatile compounds generated in serine-monosaccharide model systems,
J. Agric. Food Chem., 1998, 46, 4, 1518-1522, https://doi.org/10.1021/jf970934f
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Chen, Wang, et al., 1998
Chen, J.; Wang, M.; Ho, C.-T.,
Volatile compounds generated from thermal degradation of N-acetylglucosamine,
J. Agric. Food Chem., 1998, 46, 8, 3207-3209, https://doi.org/10.1021/jf980129g
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Buttery, Ling, et al., 1997
Buttery, R.G.; Ling, L.C.; Stern, D.J.,
Studies on popcorn aroma and flavor volatiles,
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Lu, Yu, et al., 1997
Lu, G.; Yu, T.-H.; Ho, C.-T.,
Generation of flavor compounds by the reaction of 2-deoxyglucose with selected amino acids,
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Yu, Wu, et al., 1994
Yu, T.-H.; Wu, C.-M.; Ho, C.-T.,
Volatile compounds generated from the thermal interaction of glucose and alliin or deoxyalliin in propylene glycol,
Food Chem., 1994, 51, 3, 281-286, https://doi.org/10.1016/0308-8146(94)90028-0
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Ishihara, Tsuneya, et al., 1992
Ishihara, M.; Tsuneya, T.; Shiga, M.; Kawashima, S.; Yamagishi, K.; Yoshida, F.; Sato, H.; Uneyama, K.,
New pyridine derivatives and basic components in spearmint oil (Mentha gentilis f. cardiaca) and peppermint oil (Mentha piperita),
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Flath, Matsumoto, et al., 1989
Flath, R.A.; Matsumoto, K.E.; Binder, R.G.; Cunningham, R.T.; Mon, T.R.,
Effect of pH on the volatiles of hydrolyzed protein insect baits,
J. Agric. Food Chem., 1989, 37, 3, 814-819, https://doi.org/10.1021/jf00087a053
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Mihara and Masuda, 1988
Mihara, S.; Masuda, H.,
Structure-odor relationships for disubstituted pyrazines,
J. Agric. Food Chem., 1988, 36, 6, 1242-1247, https://doi.org/10.1021/jf00084a029
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Mihara and Masuda, 1987
Mihara, S.; Masuda, H.,
Correlation between molecular structures and retention indices of pyrazines,
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Wu, Liou, et al., 1987
Wu, C.-M.; Liou, S.-E.; Chang, Y.-H.; Chiang, W.,
Volatile compounds of the wax gourd (Benincasa hispida, Cogn) and a wax gourd beverage,
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Gallois and Grimont, 1985
Gallois, A.; Grimont, P.A.D.,
Pyrazines responsible for the potatolike odor produced by some Serratia and Cedecea strains,
Appl. Environ. Microbiol., 1985, 10, 1048-1051. [all data]
Mihara and Enomoto, 1985
Mihara, S.; Enomoto, N.,
Calculation of retention indices of pyrazines on the basis of molecular structure,
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del Rosario, de Lumen, et al., 1984
del Rosario, R.; de Lumen, B.O.; Habu, T.; Flath, R.A.; Mon, T.R.; Teranishi, R.,
Comparison of headspace volatiles from winged beans and soybeans,
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. [all data]
Notes
Go To: Top, Normal alkane RI, non-polar column, temperature ramp, References
- Symbols used in this document:
Tend Final temperature Tstart Initial temperature - Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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