Lidocaine
- Formula: C14H22N2O
- Molecular weight: 234.3373
- IUPAC Standard InChIKey: NNJVILVZKWQKPM-UHFFFAOYSA-N
- CAS Registry Number: 137-58-6
- Chemical structure:
This structure is also available as a 2d Mol file or as a computed 3d SD file
The 3d structure may be viewed using Java or Javascript. - Other names: Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-; 2',6'-Acetoxylidide, 2-(diethylamino)-; α-(Diethylamino)-2,6-acetoxylidide; Anestacon; Duncaine; Gravocain; Isicaina; Isicaine; Leostesin; Lignocaine; Maricaine; Rucaina; Solcain; Xycaine; Xylestesin; Xylocain; Xylocaine; Xylocitin; Xylotox; 2-(Diethylamino)-2',6'-acetoxylidide; α-Diethylamino-2,6-dimethylacetanilide; α-Diethylaminoaceto-2,6-xylidide; ω-Diethylamino-2,6-dimethylacetanilide; Cappicaine; Cito optadren; Diethylaminoaceto-2,6-xylidide; Esracaine; L-Caine; Lida-Mantle; Xilina; Xyloneural (free base); Diethylaminoacet-2,6-xylidide; alfa-Dietilamino-2,6-dimetilacetanilide; Xilocaina; Xyline; Remicaine; Anbesol; Cuivasil; Dalcaine; Solarcaine; N-(2,6-Dimethylphenyl)-N2,N2-diethylglycinamide; Lidoderm; ELA-Max; Jetocaine
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Normal alkane RI, non-polar column, custom temperature program
Go To: Top, References, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director
Column type | Capillary | Capillary | Capillary | Capillary | Capillary |
---|---|---|---|---|---|
Active phase | 5 % Phenyl methyl siloxane | 5 % Phenyl methyl siloxane | HP-1 | Polymethylsiloxane, (PMS-20000) | Polymethylsiloxane, (PMS-20000) |
Column length (m) | 25. | 25. | 12. | 12. | |
Carrier gas | Helium | He | He | ||
Substrate | |||||
Column diameter (mm) | 0.20 | 0.20 | 0.20 | 0.20 | |
Phase thickness (μm) | 0.33 | 0.33 | 0.33 | 0.33 | |
Program | 50 0C (0.5 min) 99 0C/min -> 100 0C (1 min) 15 0C/min -> 280 0C (20 min) | 50 0C (0.5 min) 99 0C/min -> 100 0C (1 min) 15 0C/min -> 280 0C (20 min) | not specified | not specified | not specified |
I | 1924. | 1924. | 1875. | 1841. | 1842. |
Reference | Grigoriev and Savchuk, 2010 | Grigoriev and Savchuk, 2010 | Grigor'ev, Bozhko, et al., 2009 | Gambaro, Saligari, et al., 1997 | Gambaro, Saligari, et al., 1997 |
Comment | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI |
Column type | Capillary | Capillary | Capillary | Capillary | Capillary |
---|---|---|---|---|---|
Active phase | BP-1 | BP-1 | BP-1 | BP-1 | BP-1 |
Column length (m) | 12. | 12. | 12. | 12. | 12. |
Carrier gas | He | He | He | He | He |
Substrate | |||||
Column diameter (mm) | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 |
Phase thickness (μm) | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
Program | 120 0X 8 0C/min -> 270 0C 25 0C/min -> 300 0C (5 min) | 120 0X 8 0C/min -> 270 0C 25 0C/min -> 300 0C (5 min) | 120 0X 8 0C/min -> 270 0C 25 0C/min -> 300 0C (5 min) | 120 0X 8 0C/min -> 270 0C 25 0C/min -> 300 0C (5 min) | 120 0X 8 0C/min -> 270 0C 25 0C/min -> 300 0C (5 min) |
I | 1856. | 1857. | 1857. | 1858. | 1858. |
Reference | Stowell and Wilson, 1985 | Stowell and Wilson, 1985 | Stowell and Wilson, 1985 | Stowell and Wilson, 1985 | Stowell and Wilson, 1985 |
Comment | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI | MSDC-RI |
Column type | Capillary | Other |
---|---|---|
Active phase | BP-1 | Methyl Silicone |
Column length (m) | 12. | |
Carrier gas | He | |
Substrate | ||
Column diameter (mm) | 0.22 | |
Phase thickness (μm) | 0.25 | |
Program | not specified | not specified |
I | 1860. | 1870. |
Reference | Stowell and Wilson, 1985 | Ardrey and Moffat, 1981 |
Comment | MSDC-RI | MSDC-RI |
References
Go To: Top, Normal alkane RI, non-polar column, custom temperature program, Notes
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Grigoriev and Savchuk, 2010
Grigoriev, A.M.; Savchuk, S.A.,
Correlation of the parameters of screening libraries of the gas-chromatographic retention data,
Rus. J. Anal. Chem. (Engl. Transl.), 2010, 65, 4, 388-397. [all data]
Grigor'ev, Bozhko, et al., 2009
Grigor'ev, A.M.; Bozhko, E.S.; Rudakova, L.V.,
Use of correlation between retention indices on low-polarity phases for screening comp-lex mixtures by gas chromatography-mass spectrometry,
Rus. J. Anal. Chem., 2009, 64, 2, 140-143, https://doi.org/10.1134/S1061934809020087
. [all data]
Gambaro, Saligari, et al., 1997
Gambaro, V.; Saligari, E.; Froldi, R.; Bianchi, L.,
Analysis of street drugs by means of HRGC,
Bollettino Chimico Farmaceutica, 1997, 36, 4, 359-367. [all data]
Stowell and Wilson, 1985
Stowell, A.; Wilson, L.,
Use of retention indices in drug screening by capillary gas chromatography, Rep. # CD 2362, Department of Scientific and Industrial Reseach, Chemistry Division, Lower Hutt, NZ, 1985, 32. [all data]
Ardrey and Moffat, 1981
Ardrey, R.E.; Moffat, A.C.,
Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase,
J. Chromatogr., 1981, 220, 3, 195-252, https://doi.org/10.1016/S0021-9673(00)81925-1
. [all data]
Notes
Go To: Top, Normal alkane RI, non-polar column, custom temperature program, References
- Data from NIST Standard Reference Database 69: NIST Chemistry WebBook
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